Our research looks at mood instability, which means frequent and sudden changes in emotions that are hard to control. This is common in many mental health conditions and can lead to behaviors like self-harm. For young people, it’s often one of the first signs that something is wrong. Despite its clinical significance, we still don’t fully understand what causes it, and there aren’t many early interventions designed to help.
Our team works together with young people experts by experience to better understand what maintains mood instability and to develop new therapies, with a particular focus on mental imagery. All our studies are supported by a Young People Advisory Group. We use a range of different disciplines such as psychiatry, experimental psychopathology, psychopharmacology, and cognitive neurosciences. We use digital tools to track symptoms, understand how they work and create new treatments.
Our key research questions:
- What are the cognitive mechanisms that drive mood instability and associated behaviours?
- Can we translate neurocognitive findings into developing new brief early interventions for young people experiencing mood instability and associated behaviours?
- What happens to young people who experience mood instability in and outside clinical services?
You can find our team values here.
Our studies
Experimental Studies
We aim to understand the cognitive mechanisms that drive mood instability and associated behaviours, such as self-harm, using a variety of methods including behavioural experiments, neuroimaging, physiological measurements, cognitive and pharmacological manipulation to identify targets for new treatments.
Recent/ongoing projects:
Treatment Development Studies
We aim to develop new early interventions to support young people with mood instability across different mental disorders, focusing on mental imagery-based cognitive techniques and digital tools.
Recent/ongoing projects:
Our Team
Research team
Dr Martina Di Simplicio
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Dr Martina Di Simplicio
Clinical Senior Lecturer in Psychiatry
Dr Mariane Furtado
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Dr Mariane Furtado
Research Associate in Health Informatics and NHS Clinical Informatics
Miss Joanna Vamvakopoulou
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Miss Joanna Vamvakopoulou
PhD Student
Miss Aglaia Freccero
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Miss Aglaia Freccero
PhD Student
Miss Bhavika Dulabh
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Miss Bhavika Dulabh
Research Assistant
Miss Athina Servi
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Miss Athina Servi
Research Assistant
Other team affliates
Miss Minseo Cho - PhD Student, Dyson School of Design Engineering
Miss Anna Caltabiano - PhD Student, Dyson School of Design Engineering
Dr Alex Lau-Zhu - MRC Clinician Scientist, University of Oxford; Honorary Research Associate
Mr Anthony Wang - Undergraduate Honorary Research Assistant