Imperial College London
Portrait Picture

Professor Aldo Faisal

Faculty of Engineering, Department of Bioengineering

Professor of AI & Neuroscience
 
 
 
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Contact

 

+44 (0)20 7594 6373a.faisal Website

 
 
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Assistant

 

Miss Teresa Ng +44 (0)20 7594 8300

 
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Location

 

4.08Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Kadirvelu:2022:10.1016/j.eclinm.2022.101317,
author = {Kadirvelu, B and Burcea, G and Costello, C and Quint, J and Faisal, A},
doi = {10.1016/j.eclinm.2022.101317},
journal = {EClinicalMedicine},
pages = {1--15},
title = {Variation in global COVID-19 symptoms by geography and by chronic disease: a global survey using the COVID-19 Symptom Mapper},
url = {http://dx.doi.org/10.1016/j.eclinm.2022.101317},
volume = {45},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundCOVID-19 is typically characterised by a triad of symptoms: cough, fever and loss of taste and smell, however, this varies globally. This study examines variations in COVID-19 symptom profiles based on underlying chronic disease and geographical location.MethodsUsing a global online symptom survey of 78,299 responders in 190 countries between 09/04/2020 and  22/09/2020, we conducted an exploratory study to examine symptom profiles associated with a positive COVID-19 test result by country and underlying chronic disease (single, co- or multi-morbidities) using statistical and machine learning methods.FindingsFrom the results of 7980 COVID-19 tested positive responders, we find that symptom patterns differ by country. For example, India reported a lower proportion of headache (22.8% vs 47.8%, p<1e-13) and itchy eyes (7.3% vs. 16.5%, p=2e-8) than other countries. As with geographic location, we find people differed in their reported symptoms if they suffered from specific chronic diseases. For example, COVID-19 positive responders with asthma (25.3% vs. 13.7%, p=7e-6) were more likely to report shortness of breath compared to those with no underlying chronic disease. InterpretationWe have identified variation in COVID-19 symptom profiles depending on geographic location and underlying chronic disease. Failure to reflect this symptom variation in public health messaging may contribute to asymptomatic COVID-19 spread and put patients with chronic diseases at a greater risk of infection. Future work should focus on symptom profile variation in the emerging variants of the SARS-CoV-2 virus. This is crucial to speed up clinical diagnosis, predict prognostic outcomes and target treatment.
AU  - Kadirvelu,B
AU  - Burcea,G
AU  - Costello,C
AU  - Quint,J
AU  - Faisal,A
DO  - 10.1016/j.eclinm.2022.101317
EP  - 15
PY  - 2022///
SN  - 2589-5370
SP  - 1
TI  - Variation in global COVID-19 symptoms by geography and by chronic disease: a global survey using the COVID-19 Symptom Mapper
T2  - EClinicalMedicine
UR  - http://dx.doi.org/10.1016/j.eclinm.2022.101317
UR  - https://www.sciencedirect.com/science/article/pii/S2589537022000475?via%3Dihub
UR  - http://hdl.handle.net/10044/1/94420
VL  - 45
ER  -
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