Imperial College London
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ProfessorFrankKelly

Faculty of Medicine, School of Public Health

Battcock Chair in Community Health and Policy
 
 
 
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Contact

 

+44 (0)20 7594 8098 ext 48098frank.kelly Website

 
 
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Location

 

Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Li:2023:10.1016/j.envint.2022.107665,
author = {Li, J and Cai, YS and Kelly, FJ and Wooster, MJ and Han, Y and Zheng, Y and Guan, T and Li, P and Zhu, T and Xue, T},
doi = {10.1016/j.envint.2022.107665},
journal = {Environment International},
title = {Landscape fire smoke enhances the association between fine particulate matter exposure and acute respiratory infection among children under 5 years of age: findings of a case-crossover study for 48 low- and middle-income countries},
url = {http://dx.doi.org/10.1016/j.envint.2022.107665},
volume = {171},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundFine particulate matter (PM2.5) produced by landscape fires is thought to be more toxic than that from non-fire sources. However, the effects of “fire-sourced” PM2.5 on acute respiratory infection (ARI) are unknown.MethodsWe combined Demographic and Health Survey (DHS) data from 48 countries with gridded global estimates of PM2.5 concentrations from 2003 to 2014. The proportions of fire-sourced PM2.5 were assessed by a chemical transport model using a variety of PM2.5 source data. We tested for associations between ARI and short-term exposure to fire- and “non-fire-sourced” PM2.5 using a bidirectional case-crossover analysis. The robustness and homogeneity of the associations were examined by sensitivity analyses. We also established a nonlinear exposure–response relationship between fire- and non-fire-sourced PM2.5 and ARI using a two-dimensional spline function.ResultsThe study included 36,432 children under 5 years who reported ARI symptoms. Each 1 µg/m3 increment of fire-sourced PM2.5 was associated with a 3.2 % (95 % confidence interval [CI] 0.2, 6.2) increment in the risk of ARI. This effect was comparable to that of each ∼5 µg/m3 increment in PM2.5 from non-fire sources (3.1 %; 95 % CI 2.4, 3.7). The association between ARI and total PM2.5 concentration was significantly mediated by the proportion of fire-sourced particles. Nonlinear analysis showed that the risk of ARI was increased by both fire- and non-fire-sourced PM2.5, but especially by the former.ConclusionsPM2.5 produced by landscape fire was more strongly associated to ARI among children under 5 years than that from non-fire sources.
AU  - Li,J
AU  - Cai,YS
AU  - Kelly,FJ
AU  - Wooster,MJ
AU  - Han,Y
AU  - Zheng,Y
AU  - Guan,T
AU  - Li,P
AU  - Zhu,T
AU  - Xue,T
DO  - 10.1016/j.envint.2022.107665
PY  - 2023///
SN  - 0160-4120
TI  - Landscape fire smoke enhances the association between fine particulate matter exposure and acute respiratory infection among children under 5 years of age: findings of a case-crossover study for 48 low- and middle-income countries
T2  - Environment International
UR  - http://dx.doi.org/10.1016/j.envint.2022.107665
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000898082800003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://www.sciencedirect.com/science/article/pii/S016041202200592X
UR  - http://hdl.handle.net/10044/1/110125
VL  - 171
ER  -
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