Imperial College London
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ProfessorFrankKelly

Faculty of Medicine, School of Public Health

Battcock Chair in Community Health and Policy
 
 
 
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Contact

 

+44 (0)20 7594 8098 ext 48098frank.kelly Website

 
 
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Location

 

Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Yang:2023:10.1001/jamapsychiatry.2022.4812,
author = {Yang, T and Wang, J and Huang, J and Kelly, FJJ and Li, G},
doi = {10.1001/jamapsychiatry.2022.4812},
journal = {JAMA Psychiatry},
pages = {305--313},
title = {Long-term exposure to multiple ambient air pollutants and association with incident depression and anxiety},
url = {http://dx.doi.org/10.1001/jamapsychiatry.2022.4812},
volume = {80},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Importance: Air pollution is increasingly recognized as an important environmental risk factor for mental health. However, epidemiologic evidence on long-term exposure to low levels of air pollutants with incident depression and anxiety is still very limited.Objectives: To investigate the association of long-term joint exposure to multiple air pollutants with incident depression and anxiety.Design, setting, and participants: This prospective, population-based cohort study used data from the UK Biobank. The participants were recruited between March 13, 2006, and October 1, 2010, and included individuals who had never been diagnosed with depression or anxiety at baseline and had full information on exposure and covariates. Data were analyzed from May 1 to October 10, 2022.Exposures: Annual mean air pollution concentrations of particulate matter (PM) with aerodynamic diameter of 2.5 μm or less (PM2.5) and PM with aerodynamic diameter between 2.5 μm and 10 μm (PM2.5-10). Nitrogen dioxide (NO2) and nitric oxide (NO) were estimated for each participant's residential address using the land use regression model, and joint exposure to air pollution reflected by air pollution score was calculated by principal components analysis.Main outcomes and measures: Incidence of diagnosed depression (F32-F33) and anxiety (F40-F48) were ascertained with International Statistical Classification of Diseases and Related Health Problems, Tenth Revision codes.Results: During a median (IQR) follow-up of 10.9 (10.1-11.6) years, among 389 185 participants (mean [SD] age, 56.7 [8.1] years, 205 855 female individuals [52.9%]), a total of 13 131 and 15 835 patients were diagnosed with depression and anxiety, respectively. The median (IQR) concentration of pollutants was as follows: PM2.5, 9.9 (9.3-10.6) μg/m3; PM2.5-10, 6.1 (5.8-6.6) μg/m3; NO2, 26.0 (21.3-31.1) μg/m3; and NO, 15.9 (11.6-20.6) μg/m3. Long-term estimated exposure to multiple air pollutants was associated with i
AU  - Yang,T
AU  - Wang,J
AU  - Huang,J
AU  - Kelly,FJJ
AU  - Li,G
DO  - 10.1001/jamapsychiatry.2022.4812
EP  - 313
PY  - 2023///
SN  - 2168-622X
SP  - 305
TI  - Long-term exposure to multiple ambient air pollutants and association with incident depression and anxiety
T2  - JAMA Psychiatry
UR  - http://dx.doi.org/10.1001/jamapsychiatry.2022.4812
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000926119600002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2801116
VL  - 80
ER  -
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