Selected Publications
Journal articles
- Lim M, Shunjie C, Panoskaltsis N, et al, Systematic experimental design for bioprocess characterization: Elucidating transient effects of multi-cytokine contributions on erythroid differentiation, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, 2012, Vol:17, Pages:218-226, ISSN:1226-8372
- Consolo F, Bariani C, Mantalaris A, et al, Computational modeling for the optimization of a cardiogenic 3D bioprocess of encapsulated embryonic stem cells, BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2012, Vol:11, Pages:261-277, ISSN:1617-7959
- Kallala R, Graham SM, Nikkhah D, et al, In vitro and in vivo effects of antibiotics on bone cell metabolism and fracture healing, EXPERT OPINION ON DRUG SAFETY, 2012, Vol:11, Pages:15-32, ISSN:1474-0338
- Ho Y, Kiparissides A, Pistikopoulos EN, et al, Computational approach for understanding and improving GS-NS0 antibody production under hyperosmotic conditions., J Biosci Bioeng, 2012, Vol:113, Pages:88-98
- Siti-Ismail N, Samadikuchaksaraei A, Bishop AE, et al, Development of a Novel Three-Dimensional, Automatable and Integrated Bioprocess for the Differentiation of Embryonic Stem Cells into Pulmonary Alveolar Cells in a Rotating Vessel Bioreactor System., Tissue Eng Part C Methods, 2012
- Ripamonti U, Tsiridis E, Ferretti C, et al, Perspectives in regenerative medicine and tissue engineering of bone, BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 2011, Vol:49, Pages:507-509, ISSN:0266-4356
- Mortera-Blanco T, Mantalaris A, Bismarck A, et al, Long-term cytokine-free expansion of cord blood mononuclear cells in three-dimensional scaffolds., Biomaterials, 2011, Vol:32, Pages:9263-9270
- Lim M, Panoskaltsis N, Ye H, et al, Optimization of in vitro erythropoiesis from CD34(+) cord blood cells using design of experiments (DOE), BIOCHEMICAL ENGINEERING JOURNAL, 2011, Vol:55, Pages:154-161, ISSN:1369-703X
- Koutinas M, Kiparissides A, Lam M-C, et al, Improving the prediction of Pseudomonas putida mt-2 growth kinetics with the use of a gene expression regulation model of the TOL plasmid, BIOCHEMICAL ENGINEERING JOURNAL, 2011, Vol:55, Pages:108-118, ISSN:1369-703X
- Graham SM, Howgate D, Anderson W, et al, Risk of osteoporosis and fracture incidence in patients on antipsychotic medication, EXPERT OPINION ON DRUG SAFETY, 2011, Vol:10, Pages:575-602, ISSN:1474-0338
- Kiparissides A, Koutinas M, Kontoravdi C, et al, Closing the loop in biological systems modelling - From the in Silico to the in Vitro, AUTOMATICA Special Issue on Systems Biology, 2011, Vol:47, Pages:1147-1155
- Mantalaris A, Bioprocess Systems Engineering: bridging the 'scales' between 'molecules, cells & processes', MICROBIAL BIOTECHNOLOGY, 2011, Vol:4, Pages:121-124, ISSN:1751-7907
- Quero F, Nogi M, Lee K-Y, et al, Cross-Linked Bacterial Cellulose Networks Using Glyoxalization, ACS APPLIED MATERIALS & INTERFACES, 2011, Vol:3, Pages:490-499, ISSN:1944-8244
- Seong JM, Kim B-C, Park J-H, et al, Stem cells in bone tissue engineering, BIOMEDICAL MATERIALS, 2010, Vol:5, ISSN:1748-6041
- Kiparissides A, Koutinas M, Moss T, et al, Modelling the Delta1/Notch1 pathway: in search of the mediator(s) of neural stem cell differentiation., PLoS One, 2011, Vol:6
- Koutinas M, Kiparissides A, Silva-Rocha R, et al, Linking genes to microbial growth kinetics: an integrated biochemical systems engineering approach., Metab Eng, 2011, Vol:13, Pages:401-413
- Kuzin I, Sun H, Moshkani S, et al, Long-term immunologically competent human peripheral lymphoid tissue cultures in a 3D bioreactor., Biotechnol Bioeng, 2011, Vol:108, Pages:1430-1440
- Ferretti C, Ripamonti U, Tsiridis E, et al, Osteoinduction: translating preclinical promise into clinical reality, BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 2010, Vol:48, Pages:536-539, ISSN:0266-4356
- Yue X, Drakakis EM, Mantalaris A, et al, Generation of spatio-temporal concentration profiles for cell culture systems: A case study in ammonia, MEASUREMENT, 2010, Vol:43, Pages:1207-1216, ISSN:0263-2241
- Kontoravdi C, Pistikopoulos EN, Mantalaris A, Systematic development of predictive mathematical models for animal cell cultures, Computers & Chemical Engineering, 2010, Vol:34, Pages:1192-1198
- Lim Y, Mantalaris A, Yap MG, et al, Simultaneous targeting of Requiem & Alg-2 in Chinese hamster ovary cells for improved recombinant protein production., Mol Biotechnol, 2010, Vol:46, Pages:301-307
- Pagkalos J, Cha JM, Kang Y, et al, Simvastatin induces osteogenic differentiation of murine embryonic stem cells., J Bone Miner Res, 2010, Vol:25, Pages:2470-2478
- Koutinas M, Lam MC, Kiparissides A, et al, The regulatory logic of m-xylene biodegradation by Pseudomonas putida mt-2 exposed by dynamic modelling of the principal node Ps/Pr of the TOL plasmid., Environ Microbiol, 2010, Vol:12, Pages:1705-1718
- Graham SM, Leonidou A, Aslam-Pervez N, et al, Biological therapy of bone defects: the immunology of bone allo-transplantation, EXPERT OPINION ON BIOLOGICAL THERAPY, 2010, Vol:10, Pages:885-901, ISSN:1471-2598
- Heliotis M, Ripamonti U, Ferretti C, et al, The basic science of bone induction., Br J Oral Maxillofac Surg, 2009, Vol:47, Pages:511-514
- Yue X, Drakakis EM, Lim M, et al, A Real-Time Multi-Channel Monitoring System for Stem Cell Culture Process, IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, 2008, Vol:2, Pages:66-77, ISSN:1932-4545
- Lim Y, Seah VX, Mantalaris A, et al, Elucidating the role of requiem in the growth and death of Chinese hamster ovary cells., Apoptosis, 2010, Vol:15, Pages:450-462
- Blanco TM, Mantalaris A, Bismarck A, et al, The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia., Biomaterials, 2010, Vol:31, Pages:2243-2251
- Howgate DJ, Gamie Z, Panteliadis P, et al, The potential adverse effects of aromatase inhibitors on wound healing: in vitro and in vivo evidence, EXPERT OPINION ON DRUG SAFETY, 2009, Vol:8, Pages:523-535, ISSN:1474-0338
- Kiparissides A, Kucherenko SS, Mantalaris A, et al, Global Sensitivity Analysis Challenges in Biological Systems Modeling, INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2009, Vol:48, Pages:7168-7180, ISSN:0888-5885
- Tran GT, Pagkalos J, Tsiridis E, et al, Growth hormone: does it have a therapeutic role in fracture healing?, EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2009, Vol:18, Pages:887-911, ISSN:1354-3784
- Graham S, Gamie Z, Polyzois I, et al, Prostaglandin EP2 and EP4 receptor agonists in bone formation and bone healing: In vivo and in vitro evidence, EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2009, Vol:18, Pages:749-766, ISSN:1354-3784
- Tang QO, Shakib K, Heliotis M, et al, TGF-beta 3: A potential biological therapy for enhancing chondrogenesis, EXPERT OPINION ON BIOLOGICAL THERAPY, 2009, Vol:9, Pages:689-701, ISSN:1471-2598
- Placzek MR, Chung I-M, Macedo HM, et al, Stem cell bioprocessing: fundamentals and principles, JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2009, Vol:6, Pages:209-232, ISSN:1742-5689
- Kang Y, Nagy JM, Polak JM, et al, Proteomic Characterization of the Conditioned Media Produced by the Visceral Endoderm-Like Cell Lines HepG2 and END2: Toward a Defined Medium for the Osteogenic/Chondrogenic Differentiation of Embryonic Stem Cells, STEM CELLS AND DEVELOPMENT, 200 9, Vol:18, Pages:77-91, ISSN:1547-3287
- Zhang J, Wang M, Cha JM, et al, The incorporation of 70s bioactive glass to the osteogenic differentiation of murine embryonic stem cells in 3D biore actors, Journal of Tissue Engineering and Regenerative Medicine, 2009, Vol:3, Pages:63-71, ISSN:1932-6254
- Kang Y, Techanukul T, Mantalaris A, et al, Comparison of three commercially available DIGE analysis software packages: minimal user intervention in gel-based proteomics., J Proteome Res, 2009, Vol:8, Pages:1077-1084, ISSN:1535-3893
- Polak JM, Mantalaris S, Stem cells bioprocessing: an important milestone to move regenerative medicine research into the clinical arena., Pediatr Res, 2008, Vol:63, Pages:461-466, ISSN:0031-3998
- Kumar R, Panoskaltsis N, Stepanek F, et al, Coupled oxygen-carbon dioxide transport model for the human bone marrow, FOOD AND BIOPRODUCTS PROCESSING, 2008, Vol:86, Pages:211-219, ISSN:0960-3085
- Hwang Y-S, Polak JM, Mantalaris A, In Vitro Direct Chondrogenesis of Murine Embryonic Stem Cells by Bypassing Embryoid Body Formation, STEM CELLS AND DEVELOPMENT, 2008, Vol:17, Pages:971-978, ISSN:1547-3287
- Hwang Y-S, Polak JM, Mantalaris A, In Vitro Direct Osteogenesis of Murine Embryonic Stem Cells Without Embryoid Body Formation, STEM CELLS AND DEVELOPMENT, 2008, Vol:17, Pages:963-970, ISSN:1547-3287
- Radomska A, Singhal S, Ye H, et al, Biocompatible ion selective electrode for monitoring metabolic activity during the growth and cultivation of human cells, BIOSENSORS & BIOELECTRONICS, 2008, Vol:24, Pages:435-441, ISSN:0956-5663
- Hwang YS, Cho J, Tay F, et al, The use of murine embryonic stem cells, alginate encapsulation, and rotary microgravity bioreactor in bone tissue engineering., Biomaterials, 2009, Vol:30, Pages:499-507
- Siti-Ismail N, Bishop AE, Polak JM, et al, The benefit of human embryonic stem cell encapsulation for prolonged feeder-free maintenance, BIOMATERIALS, 2008, Vol:29, Pages:3946-3952, ISSN:0142-9612
- Juntaro J, Pommet M, Kalinka G, et al, Creating hierarchical structures in renewable composites by attaching bacterial cellulose onto sisal fibers, ADVANCED MATERIALS, 2008, Vol:20, Pages:3122-3126, ISSN:0935-9648
- Lim M, Ye H, Drakakis EM, et al, Towards information-rich bioprocessing: Generation of spatio-temporal profiles through the use of design of experiments to determine optimal number and location of sensors - An example in thermal profiles, BIOCHEMICAL ENGINEERING JOURNAL, 2008, Vol:40, Pages:1-7, ISSN:1369-703X
- Pommet M, Juntaro J, Heng JYY, et al, Surface modification of natural fibers using bacteria: Depositing bacterial cellulose onto natural fibers to create hierarchical fiber reinforced nanocomposites, BIOMACROMOLECULES, 2008, Vol:9, Pages:1643-1651, ISSN:1525-7797
- Chung IM, Enemchukwu NO, Khaja SD, et al, Bioadhesive hydrogel microenvironments to modulate epithelial morphogenesis., Biomaterials, 2008, Vol:29, Pages:2637-2645, ISSN:0142-9612
- Hwang Y-S, Bishop AE, Polak JM, et al, Enhanced in vitro chondrogenic differentiation of murine embryonic stem cells, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, 2007, Vol:12, Pages:696-706, ISSN:1226-8372
- Juntaro J, Pommet M, Mantalaris A, et al, Nanocellulose enhanced interfaces in truly green unidirectional fibre reinforced composites, COMPOSITE INTERFACES, 2007, Vol:14, Pages:753-762, ISSN:0927-6440
- Randle WL, Cha JM, Hwang Y-S, et al, Integrated 3-dimensional expansion and osteogenic differentiation of murine embryonic stem cells, TISSUE ENGINEERING, 2007, Vol:13, Pages:2957-2970, ISSN:1076-3279
- Baptista IIR, Zhou NY, Emanuelsson EAC, et al, Evidence of species succession during chlorobenzene biodegradation, BIOTECHNOLOGY AND BIOENGINEERING, 2008, Vol:99, Pages:68-74, ISSN:0006-3592
- Safinia L, Wilson K, Mantalaris A, et al, Through-thickness plasma modification of biodegradable and nonbiodegradable porous polymer constructs., J Biomed Mater Res A, 2008, Vol:87, Pages:632-642
- Koutinas M, Baptista IIR, Meniconi A, et al, The use of an oil-absorber-bioscrubber system during biodegradation of sequentially alternating loadings of 1,2-dichloroethane and fluorobenzene in a waste gas, CHEMICAL ENGINEERING SCIENCE, 2007, Vol:62, Pages:5989-6001, ISSN:0009-2509
- Baptista IIR, Peeva LG, Zhou N-Y, et al, Stability and performance of Xanthobacter autotrophicus GJ10 during 1,2-dichloroethane biodegradation (vol 72, pg 4411, 2006), APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2007, Vol:73, Pages:6326-6326, ISSN:0099-2240
- Kontoravdi C, Wong D, Lam C, et al, Modeling amino acid metabolism in mammalian cells-toward the development of a model library., Biotechnol Prog, 2007, Vol:23, Pages:1261-1269, ISSN:8756-7938
- Mantalaris A, Keng P, Bourne P, et al, Engineering a human bone marrow model: a case study on ex vivo erythropoiesis., Biotechnol Prog, 1998, Vol:14, Pages:126-133, ISSN:8756-7938
- Waugh RE, Mantalaris A, Bauserman RG, et al, Membrane instability in late-stage erythropoiesis., Blood, 2001, Vol:97, Pages:1869-1875, ISSN:0006-4971
- Mantalaris A, Panoskaltsis N, Sakai Y, et al, Localization of androgen receptor expression in human bone marrow., J Pathol, 2001, Vol:193, Pages:361-366, ISSN:0022-3417
- Omasa T, Chen YG, Mantalaris A, et al, A cDNA from human bone marrow encoding a protein exhibiting homology to the ATP1gamma1/PLM/MAT8 family of transmembrane proteins., Biochim Biophys Acta, 2001, Vol:1517, Pages:307-310, ISSN:0006-3002
- Omasa T, Chen YG, Mantalaris A, et al, Molecular cloning and sequencing of the human heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase from bone marrow culture., DNA Seq, 2002, Vol:13, Pages:133-137, ISSN:1042-5179
- Ma CYJ, Kumar R, Xu XY, et al, A combined fluid dynamics, mass transport and cell growth model for a three-dimensional perfused biorector for tissue engineering of haematopoietic cells, BIOCHEMICAL ENGINEERING JOURNAL, 2007, Vol:35, Pages:1-11, ISSN:1369-703X
- Hwang Y-S, Kang Y, Mantalaris A, Directing embryonic stem cell differentiation into osteogenic/chondrogenic lineage in vitro, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, 2007, Vol:12, Pages:15-21, ISSN:1226-8372
- Lim M, Ye H, Panoskaltsis N, et al, Intelligent bioprocessing for haemotopoietic cell cultures using monitoring and design of experiments., Biotechnol Adv, 2007, Vol:25, Pages:353-368, ISSN:0734-9750
- Safinia L, Wilson K, Mantalaris A, et al, Atmospheric plasma treatment of porous polymer constructs for tissue engineering applications., Macromol Biosci, 2007, Vol:7, Pages:315-327, ISSN:1616-5187
- Ho Y, Varley J, Mantalaris A, Development and analysis of a mathematical model for antibody-producing GS-NS0 cells under normal and hyperosmotic culture conditions., Biotechnol Prog, 2006, Vol:22, Pages:1560-1569, ISSN:8756-7938
- Sidoli FR, Mantalaris A, Asprey SP, Modelling of mammalian cells and cell culture processes, CYTOTECHNOLOGY, 2004, Vol:44, Pages:27-46, ISSN:0920-9069
- Coward SM, Selden C, Mantalaris A, et al, Proliferation rates of HepG2 cells encapsulated in alginate are increased in a microgravity environment compared with static cultures, ARTIFICIAL ORGANS, 2005, Vol:29, Pages:152-158, ISSN:0160-564X
- Sidoli FR, Asprey SP, Mantalaris A, A coupled single cell-population-balance model for mammalian cell cultures, IND U STRIAL & ENGINEERING CHEMISTRY RESEARCH, 2006, Vol:45, Pages:5801-5811, ISSN:0888-5885
- Baptista II, Peeva LG, Zhou NY, et al, Stability and performance of Xanthobacter autotrophicus GJ10 during 1,2-dichloroethane biodegradation., Appl Environ Microbiol, 2006, Vol:72, Pages:4411-4418, ISSN:0099-2240
- Hwang YS, Randle WL, Bielby RC, et al, Enhanced derivation of osteogenic cells from murine embryonic stem cells after treatment with HepG2-condit i o ned medium and modulation of the embryoid body formation period: application to skeletal tissue engineering., Tissue Eng, 2006, Vol:12, Pages:1381-1392, ISSN:1076-3279
- Safinia L, Mantalaris A, Bismarck A, Nondestructive technique for the characterization of the pore size distribution of soft porous constructs for tissue engineering, LANGMUIR, 2006, Vol:22, Pages:3235-3242, ISSN:0743-7463
- Koutinas M, Martin J, Peeva LG, et al, An oil-absorber-bioscrubber system to stabilize biotreatment of pollutants present in waste gas. Fluctuating loads of 1,2-dichloroethane, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2006, Vol:40, Pages:595-602, ISSN:0013-936X
- Emanuelsson EAC, Baptista IIR, Mantalaris A, et al, Strain stability in biological systems treating recalcitrant organic compounds, BIOTECHNOLOGY AND BIOENGINEERING, 2005, Vol:92, Pages:843-849, ISSN:0006-3592
- Safinia L, Datan N, Hohse M, et al, Towards a methodology for the effective surface modification of porous polymer scaffolds, BIOMATERIALS, 2005, Vol:26, Pages:7537-7547, ISSN:0142-9612
- Kontoravdi C, Asprey SP, Pistikopoulos EN, et al, Application of global sensitivity analysis to determine goals for design of experiments: An example study on antibody-producing cell cultures, BIOTECHNOLOGY PROGRESS, 2005, Vol:21, Pages:1128-1135, ISSN:8756-7938
- Panoskaltsis N, Mantalaris A, Wu JHD, Engineering a mimicry of bone marrow tissue ex vivo, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2005, Vol:100, Pages:28-35, ISSN:1389-1723
- Safinia L, Blaker JJ, Maquet V, et al, Characterisation of 'wet' polymer surfaces for tissue engineering applications: Are flat surfaces a suitable model for complex structures?, E-POLYMERS, 2005, ISSN:1618-7229
- Sidoli FR, Mantalaris A, Asprey SP, Toward global parametric estimability of a large-scale kinetic single-cell model for mammalian cell cultures, INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2005, Vol:44, Pages:868-878, ISSN:0888-5885
- Wu MH, Dirnopoulos G, Mantalaris A, et al, The effect of hyperosmotic pressure on antibody production and gene expression in the GS-NS0 cell line, BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 2004, Vol:40, Pages:41-46, ISSN:0885-4513
- Kumar R, Stepanek F, Mantalaris A, An oxygen transport model for human bone marrow microcirculation, FOOD AND BIOPRODUCTS PROCESSING, 2004, Vol:82, Pages:105-116, ISSN:0960-3085
- Mantalaris A, Tissue engineering: a passing fad or a viable field for chemical engineers?, CHEMICAL ENGINEER-LONDON, 2001, Pages:32-34, ISSN:0302-0797
Books
- Polak J, Mantalaris S, Harding S, Advances In Tissue Engineering, London, Imperial College Press, 2008, ISBN:9781848161825(publication)
Book chapters
- E, H., CUI, Z. F., ELLIS, M. J., MACEDO, H. & MANTALARIS, A. 2010. Hollow Fiber Membrane Bioreactor Technology for Tissue Engineering and Stem Cell Therapy. In: ENRICO, D. & LIDIETTA, G. (eds.) Comprehensive Membrane Science and Engineering. Oxford: Elsevier.
- Safinia, L., N. Panoskaltsis, A. Mantalaris 2005. Bone Marrow Tissue Engineering Bioreactors, in Bioreactors for Tissue Engineering: Principles, Design and Operation, M. Al-Rubeai and J. Chaudhuri, Eds., Kluwer Academic Publishers.
- Mantalaris, A. and J.H.D. Wu 2005. Ex Vivo Culture of Hematopoietic and Mesenchymal Stem Cells in Cell Culture Technology for Pharmaceutical and Cell-Based Therapies, S.S. Ozturk and W-S. Hu, Eds., Taylor & Francis Group, Inc.
- Mantalaris, A., N. Panoskaltsis, J.H.D. Wu 2004. Hematopoietic Ste m Cells and Assays, in Encyclopedia of Biomaterials and Biomedical Engineering, G.E. Wnek and G.L. Bowlin, Eds., Marcel Dekker, Inc.
- Mantalaris, A., N. Panoskaltsis, J.H.D. Wu 2004. Tissue Engineering of Bone Marrow, Culture Systems, in Encyclopedia of Biomaterials and Biomedical Engineering, G.E. Wnek and G.L. Bowlin, Eds., Marcel Dekker, Inc.
- Mantalaris, A., N. Panoskaltsis, J.H.D. Wu 2004. Tissue Engineering of Bone Mar r ow, in Encyclopedia of Biomaterials and Biomedical Engineering , G.E. Wnek and G.L. Bowlin, Eds., Marcel Dekker, Inc.
Conference
- Koutinas M, Kiparissides A, de Lorenzo V, et al, Predicting microbial growth kinetics with the use of genetic circuit models, 21st European Symposium on Computer Aided Process Engineering (ESCAPE-21), ELSEVIER SCIENCE BV, 2011, Pages:1321-1325, ISSN:1570-7946
- Pefani E, Panoskaltsis N, Mantalaris A, et al, Towards a high-fidelity model for model based optimisation of drug delivery systems in acute myeloid leukemia, 21st European Symposium on Computer Aided Process Engineering (ESCAPE-21), ELSEVIER SCIENCE BV, 2011, Pages:1505-1509, ISSN:1570-7946
- Zavitsanou S, Panoskaltsi N, Mantalaris A, et al, Modelling of the Insulin Delivery System for patients with Type 1 Diabetes Mellitus, 21st European Symposium on Computer Aided Process Engineering (ESCAPE-21), ELSEVIER SCIENCE BV, 2011, Pages:1500-1504, ISSN:1570-7946
- Krieger A, Panoskaltsis N, Mantalaris A, et al, A Novel Physiologically Based Compartmental Model for Volatile Anaesthesia, 21st European Symposium on Computer Aided Process Engineering (ESCAPE-21), ELSEVIER SCIENCE BV, 2011, Pages:1495-1499, ISSN:1570-7946
- Kiparissides A, Pistikopoulos EN, Mantalaris A, On the model based optimization of secreting mammalian cell cultures via minimal glucose provision, 21st European Symposium on Computer Aided Process Engineering (ESCAPE-21), ELSEVIER SCIENCE BV, 2011, Pages:1210-1214, ISSN:1570-7946
- Yeo D, Kiparissides A, Pistikopoulos E, et al, A combined growth kinetics, metabolism and gene expression model for 3D ESC bioprocesses, 21st European Symposium on Computer Aided Process Engineering (ESCAPE-21), ELSEVIER SCIENCE BV, 2011, Pages:1326-1330, ISSN:1570-7946
- Eichhorn SJ, Quero F, Lee K-Y, et al, Mechanics of bacterial cellulose composite interfaces, 241st National Meeting and Exposition of the American-Chemical-Society (ACS), AMER CHEMICAL SOC, 2011, ISSN:0065-7727
- Fauzi I, Panoskaltsis N, Mantalaris A, A Novel Three Dimensional (3D) Culture System for the Efficient, Single-Step Erythropoietic Differentiation of Mouse Embryonic Stern Cells (mESCs), 52nd Annual Meeting of the American-Society-of-Hematology (ASH), AMER SOC HEMATOLOGY, 2010, Pages:849-849, ISSN:0006-4971
- Blanco TM, Mantalaris A, Santiapillai J, et al, Effects of Single-Agent, Low Dose Exogenous Erythropoietin In a Long-Term In Vitro serum-Free 3D Culture of Human Cord Blood Mononuclear Cells for Directed Erythropoiesis, 52nd Annual Meeting of the American-Society-of-Hematology (ASH), AMER SOC HEMATOLOGY, 2010, Pages:154-154, ISSN:0006-4971
- Rende M, Macedo H, Livingston AG, et al, Long Term, Cytokine Free Ex Vivo Expansion of Human Cord Blood Mononuclear Cells Using a Novel Closed Loop 3D Dual Hollow Fibre Perfused Bioreactor, 2010, Pages:361-361, ISSN:0006-4971
- Blanco TM, Mantalaris A, Santiapillai J, et al, Effects of Single-Agent, Low Dose Exogenous Erythropoietin In a Long Term In Vitro serum Free 3D Culture of Human Cord Blood Mononuclear Cells for Directed Erythropoiesis, 2010, Pages:154-154, ISSN:0006-4971
- Kiparissides A, Rodriguez-Fernandez M, Kucherenko S, et al, Application of Global Sensitivity Analysis to Biological Models, 18th European Symposium on Computer Aided Process Engineering (ESCAPE-18), ELSEVIER SCIENCE BV, 2008, Pages:689-694, ISSN:1570-7946
- Lam CM, Sriyudthsak K, Kontoravdi C, et al, Cell cycle modelling for off-line dynamic optimisation of mammalian cultures, 18th European Symposium on Computer Aided Process Engineering, ELSEVIER, 2008, Pages:109-114
- Koutinas M, Kiparissides A, Lam M-C, et al, Combining Genetic Circuit and Microbial Growth Kinetic Models: A Challenge for Biological Modelling, 20th European Symposium on Computer Aided Process Engineering (ESCAPE), ELSEVIER SCIENCE BV, 2010, Pages:301-306, ISSN:1570-7946
- Kiparissides A, Pistikopoulos EN, Mantalaris A, Towards energy-based dynamic optimization of monoclonal antibody producing GS-NS0 Cultures, 20th European Symposium on Computer Aided Process Engineering (ESCAPE), ELSEVIER SCIENCE BV, 2010, Pages:589-594, ISSN:1570-7946
- Blaker JJ, Lee K-Y, Mantalaris A, et al, Ice-microsphere templating to produce highly porous nanocomposite PLA matrix scaffolds with pores selectively lined by bacterial cellulose nano-whiskers, 17th International Conference on Composite Materials, ELSEVIER SCI LTD, 2010, Pages:1879-1888, ISSN:0266-3538
- Mortera-Blanco T, Mantalaris A, Bismarck A, et al, Long-Term in Vitro Cytokine-Free and Serum-Free Culture of Human Cord Blood Mononuclear Cells in a Three-Dimensional Scaffold, 51st Annual Meeting of the American-Society-of-Hematology, AMER SOC HEMATOLOGY, 2009, Pages:208-208, ISSN:0006-4971
- Macedo H, Panoskaltsis N, Rende M, et al, A NOVEL 3D HOLLOW FIBRE REACTOR FOR THE CULTURE OF HUMAN HAEMATOPOIETIC CELLS, 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells, ELSEVIER SCIENCE INC, 2009, Pages:S101-S101, ISSN:0301-472X
- Blanco TM, Bismarck A, Mantalaris A, et al, CYTOKINE-FREE EXPANSION OF HUMAN CORD BLOOD MONONUCLEAR CELLS IN A THREE-DIMENSIONAL (3D) BIOMIMICRY, 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells, ELSEVIER SCIENCE INC, 2009, Pages:S101-S101, ISSN:0301-472X
- Fauzi I, Panoskaltsis N, Mantalaris A, SINGLE STEP ERYTHROPOIETIC CULTURE FROM MOUSE EMBRYONIC STEM CELLS (MESCS) USING HYDROGELS, HEPG2 CONDITIONED MEDIUM AND A BIOREACTOR, 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells, ELSEVIER SCIENCE INC, 2009, Pages:S67-S68, ISSN:0301-472X
- Mantalaris A, Panoskaltsis N, Song K, et al, EX VIVO EXPANSION OF ENCAPSULATED HUMAN CORD BLOOD (HCB) CD34+CELLS IN A ROTATING WALL BIOREACTOR, 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells, ELSEVIER SCIENCE INC, 2009, Pages:S9-S9, ISSN:0301-472X
- Blanco TM, Panoskaltsis N, Mantalaris S, The use of polymers in the development of an ex vivo three-dimensional (3-D) model of human acute myeloid leukemia (AML), 36th Annual Meeting of the International-Society-for-Experimental-Hematology, ELSEVIER SCIENCE INC, 2007, Pages:66-67, ISSN:0301-472X
- Sidoli FR, Mantalaris A, Asprey SP, Parametric identifiability of a structured kinetic model for mammalian cell cultures, 5th IFAC Symposium on Modelling and Control in Biomedical Systems, PERGAMON-ELSEVIER SCIENCE LTD, 2003, Pages:521-526, ISSN:0962-9505
- Kumar R, Stepanek F, Mantalaris A, A conceptual model for oxygen transport in the human marrow, 5th IFAC Symposium on Modelling and Control in Biomedical Systems, PERGAMON-ELSEVIER SCIENCE LTD, 2003, Pages:365-370, ISSN:0962-9505(abstract publication)
- Yue X, Drakakis EA, Ye H, et al, An on-line, multi-parametric, multi-channel physicochemical monitoring platform for stem cell culture bioprocessing, IEEE International Symposium on Circuits and Systems, IEEE, 2007, Pages:1215-1218, ISSN:0271-4302
- Lim M, Ye H, Panoskaltsis N, et al, In-vitro erythropoiesis of cord blood hematopoietic stem cells using design of experiments, 36th Annual Meeting of the International-Society-for-Experimental-Hematology, ELSEVIER SCIENCE INC, 2007, Pages:49-49, ISSN:0301-472X
- Asprey SP, Mantalaris A, Global parametric identifiability of a dynamic unstructured model of hybridoma cell culture, 8th IFAC International Conference on Computer Applications in Biotechnology (CAB8), 2002, Pages:25-30
- Wu MH, Dimopoulos G, Mantalaris A, et al, Effect of osmotic pressure on GS-NSO expression system, 18th Meeting of the European-Society-of-Animal-Cell-Technology (ESACT), 2005, Pages:3-13
- Kontoravdi,C. , Asprey,S.P. , Pistikopoulos,S. , et al, Dynamic model of MAb production and glycosylation for the purpose of product quality control, European Symposium on Computer-Aided Process Engineering-15, Elsevier Science Bv, 2005, Pages:307-312
- Wu,M.H. , Dimopoulos,G. , Mantalaris,A. , et al, Effect of osmotic pressure on GS-NSO expression system, 18th meeting of the European Society of Animal Cell Technology (ESACT), Granada, Spain, 11 - 14 May 2003, Dordrecht, Springer, 2005, Pages:3-13
- Kontoravdi C, Asprey SP, Pistikopoulos EN, et al, Development of a dynamic model of monoclonal antibody production and glycosylation for product quality monitoring, 15th European Symposium on Computer Aided Process Engineering (ESCAPE-15), PERGAMON-ELSEVIER SCIENCE LTD, 2007, Pages:392-400, ISSN:0098-1354
Patents
- Wu, JHD , Mantalaris, A , Panoskaltsis, N , Ex vivo generation of functional leukemia cells in a three-dimensional bioreactor, US Patent No: 7,087,431
- Wu, JHD , Osama, T , Mantalaris, A , et al, Human heme-regulated initiation factor 2.alpha kinase, U.S. Patent No. 6,562,571
Contact details
Professor Sakis Mantalaris
Head of BSEL Group
Chemical Engineering Department
Tel: +44 (0)20 7594 5601
Email:
a.mantalaris@imperial.ac.uk