Citation

BibTex format

@article{Fabbro:2016:10.1021/acsnano.5b05647,
author = {Fabbro, A and Scaini, D and León, V and Vázquez, E and Cellot, G and Privitera, G and Lombardi, L and Torrisi, F and Tomarchio, F and Bonaccorso, F and Bosi, S and Ferrari, AC and Ballerini, L and Prato, M},
doi = {10.1021/acsnano.5b05647},
journal = {ACS Nano},
pages = {615--623},
title = {Graphene-Based Interfaces Do Not Alter Target Nerve Cells.},
url = {http://dx.doi.org/10.1021/acsnano.5b05647},
volume = {10},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Neural-interfaces rely on the ability of electrodes to transduce stimuli into electrical patterns delivered to the brain. In addition to sensitivity to the stimuli, stability in the operating conditions and efficient charge transfer to neurons, the electrodes should not alter the physiological properties of the target tissue. Graphene is emerging as a promising material for neuro-interfacing applications, given its outstanding physico-chemical properties. Here, we use graphene-based substrates (GBSs) to interface neuronal growth. We test our GBSs on brain cell cultures by measuring functional and synaptic integrity of the emerging neuronal networks. We show that GBSs are permissive interfaces, even when uncoated by cell adhesion layers, retaining unaltered neuronal signaling properties, thus being suitable for carbon-based neural prosthetic devices.
AU - Fabbro,A
AU - Scaini,D
AU - León,V
AU - Vázquez,E
AU - Cellot,G
AU - Privitera,G
AU - Lombardi,L
AU - Torrisi,F
AU - Tomarchio,F
AU - Bonaccorso,F
AU - Bosi,S
AU - Ferrari,AC
AU - Ballerini,L
AU - Prato,M
DO - 10.1021/acsnano.5b05647
EP - 623
PY - 2016///
SN - 1936-086X
SP - 615
TI - Graphene-Based Interfaces Do Not Alter Target Nerve Cells.
T2 - ACS Nano
UR - http://dx.doi.org/10.1021/acsnano.5b05647
UR - https://www.ncbi.nlm.nih.gov/pubmed/26700626
VL - 10
ER -

Contact

Dr Felice Torrisi
Senior Lecturer in Chemistry of Two-Dimensional Materials

401A
Molecular Sciences Research Hub
White City Campus

f.torrisi@imperial.ac.uk
+44 (0)20 7594 5818