Publications

2018

"A High Throughput Screen for Next-Generation Leads Targeting Malaria Parasite Transmission"   Delves, M.; Miguel-Blanco, C.; Matthews, H.; Molina, I.; Ruecker, A.; Yahiya, S.; Straschil, U.; Abraham, M.; Leon, M.-L.; Fischer, O.; Zubiaurre, A.; Brandt, J. R.; Cortes, A; Barnard, A.; Fuchter, M. J.; Calderon, F.; Winzeler, E.; Sinden, R.; Herreros, E.; Gamo, F.; Baum, J.* Nature Comm. 2018, 9, Article number: 3805. DOI (Highlighted at Eurekalert and other news sites)

"Unbiased Mass Spectrometry Elucidation of the Targets and Mechanisms of Activity-Based Probes: A Case Study involving Sulfonyl Fluorides"   Chavas, T. E. J.; Fuchter, M. J.; DiMaggio, P. A.* ACS Chem. Biol. 2018, 13, 2897. DOI

Editorial for the 2018 Tetrahedron Young Investigator Award in Bioorganic and Medicinal Chemistry special issue Fuchter M. J.* Bioorg. Med. Chem. 2018, 26, 2919. DOI

"ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment" Patel, H.; Periyasamy, M.; Sava, G. P.; Bondke, A.; Slafer, B. W.; Kroll, S. H. B.; Barbazanges, M.; Starkey, R.; Ottaviani, S.; Harrod, A.; Aboagye, E. O.; Buluwela, L.; Fuchter, M. J.; Barrett, A. G. M.; Coombes, R. C.; Ali, S.* Mol. Cancer Ther. 2018, 17, 1156. DOI

"Development of a Photo-crosslinkable Diaminoquinazoline Inhibitor for Target Identification in Plasmodium falciparum" Lubin, A. S.; Zubiaurre, A. R.; Matthews, H.; Baumann, H.; Fisher, F. R.; Morales-Sanfrutos, J.; Hadavizadeh, K. S.; Nardella, F.; Tate, E. W.; Baum, J.; Scherf, A.; Fuchter, M. J.* ACS Infect. Dis. 2018, 4, 523. DOI - Invited Submission – Global Health special issue

"A computational exploration of the crystal energy and charge carrier mobility landscapes of the chiral [6]helicene molecule" Rice, B.; LeBlanc, L. M.; Otero-de-la-Roza, A.; Fuchter, M. J.; Johnson, E. R.; Nelson, J.; Jelfs, K. E.* Nanoscale 2018, 10, 1865. DOI

"Direct Reductive Amination of Carbonyl Compounds Catalyzed by a Moisture Tolerant Tin(IV) Lewis Acid" Sapsford, J. S.; Scott, D. J.; Allcock, N. J.; Fuchter, M. J.; Tighe, C. J.; Ashley, A.* Adv. Synth. Catal. 2018, 360, 1066. DOI

"Effective macrophage delivery using RAFT copolymer derived nanoparticles" Montgomery, K. S.; Davidson, R. W. M.; Cao, B.; Williams, B.; Simpson, G. W.; Nilsson, S. K.; Chiefari, J.; Fuchter, M. J.* Polym. Chem. 2018, 9, 131. DOI

2017

"Intense Redox-Driven Chiroptical Switching with a 580 mV Hysteresis Actuated Through Reversible Dimerization of an Azoniahelicene" Brandt, J. R.; Pospíšil, L.; Bednárová, L.; Correa da Costa, R.; White, A. J. P.; Mori, T.; Teplý, F.; Fuchter, M. J.* Chem.Commun. 2017, 53, 9059. DOI - inside cover article

"Emergent Properties of an Organic Semiconductor Driven by its Molecular Chirality" Yang, Y.; Rice, B.; Shi, X.; Brandt, J. R.; Correa da Costa, R.; Hedley, G. J.; Smilgies, D. –M.; Frost, J. M.; Samuel, I. D. W.; Otero-de-la-Roza, A.; Johnson, E. R.; Jelfs, K. E.; Nelson, J.; Campbell, A. J.*; Fuchter, M. J.* ACS Nano 2017, 11, 8329. DOI

"Designing effective ‘frustrated Lewis pair’ hydrogenation catalysts" Scott, D. J.*; Fuchter, M. J.; Ashley, A. E.* Chem. Soc. Rev. 2017, 46, 5689-5700. DOI

"The added value of small-molecule chirality in technological applications" Brandt, J. R.; Salerno, F.; Fuchter, M. J.* Nature Rev. Chem. 2017, 1, 0045. DOI. Access a view-only version here.

"Identification of diaminoquinazoline histone lysine methyltransferase structure activity relationships that allow for segregation of human G9a inhibition and anti-Plasmodium activity" Sundriyal, S.; Chen, P. B.; Lubin, A. S.; Lueg, G. A.; Li, F.; White, A. J. P.; Malmquist, N. A.; Vedadi, M.; Scherf, A.; Fuchter, M. J.* MedChemComm 2017, 8, 1069. DOI

"Thienopyrimidinone based sirtuin-2 (SIRT2)–selective inhibitors bind in the ligand induced 'selectivity pocket'" Sundriyal, S.; Moniot, S.; Mahmud, Z.; Yao, S.; Di Fruscia, P.; Reynolds, C. R.; Dexter, D. T.; Sternberg, M. J. E.; Lam, E. W.-F.; Steegborn, C.; Fuchter, M. J.* J. Med. Chem. 2017, 60, 1928. DOI 

"Inhibitor selectivity for CDK7 - a structural, thermodynamic and modelling study" Hazel, P.; Kroll, S. B. H.; Bondke, A.; Barbazanges, M.; Patel, H.; Fuchter, M. J.; Coombes, R. C.; Ali, S.; Barrett, A. G. M.; Freemont, P.* ChemMedChem. 2017, 12, 372. DOI

"Tuning Azoheteroarene Photoswitch Performance through Heteroaryl Design" Calbo, J.; Weston, C. E.; White, A. J. P.; Rzepa, H.; Contreras-García, J.*; Fuchter, M. J.* J. Am. Chem. Soc. 2017, 139, 1261. DOI

"Towards photopharmacological antimicrobial chemotherapy using photoswitchable amidohydrolase inhibitors" Weston, C. E.; Kraemer, A.; Colin, F.; Yildiz, O.; Baud, M. G. J.; Meyer-Almes, F. –J.; Fuchter, M. J.* ACS Infect. Dis. 2017, 3, 152. DOI

2016

"Versatile Catalytic Hydrogenation Using A Simple Tin(IV) Lewis Acid" Scott, D. J.; Phillips, N. A.; Sapsford, J. S.; Deacy, A. C.; Fuchter, M. J.; Ashley, A. E.* Angew. Chem. Int. Ed. 2016, 55, 14738. DOI

“Direct NHC-Catalysed Redox Amidation Using CO2 for Traceless Masking of Amine Nucleophiles” Davidson, R. W. D.; Fuchter, M. J.* Chem. Commun. 2016,  52, 11638. DOI (Highlighted by ChemistryWorld)

"Circularly Polarized Phosphorescent Electroluminescence with a High Dissymmetry Factor from PHOLEDs Based on a Platinahelicene" Brandt, J. R.; Wang, X.; Yang, Y.; Campbell, A.; Fuchter, M. J.* J. Am. Chem. Soc. 2016, 138, 9743. DOI

"Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites" Chen, P. B.; Ding, S.; Zanghì, G.; Foulard  V.; DiMaggio, P. A.; Fuchter, M. J.; Mecheri, S.; Mazier, D.; Scherf, A.; Malmquist, N. A.* Sci. Rep. 2016,  6, Article number: 21802. DOI

"Photoswitchable basicity through the use of azoheteroarenes" Weston, C.; Richardson, R.; Fuchter, M. J.* Chem. Commun. 2016,  52, 4521. DOI

2015

"Young Career Focus: Dr. Matthew J. Fuchter" Synthesis 2015,  47, A150. DOI

"A Facile Protocol for Water-Tolerant ‘Frustrated Lewis Pair’-Catalyzed Hydrogenation" Scott, D. J.; Simmons, T. R.; Lawrence, E. J.; Wildgoose, G. G.; Fuchter, M. J.; Ashley, A. E.* ACS Catal. 2015,  5, 5540. DOI

"Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells" Curry, E.; Green, I.; Chapman-Rothe, N.; Shamsaei, E.; Kandil, S.; Cherblanc, F. L.; Payne, L.; Bell, E.; Ganesh, T.; Srimongkolpithak, N.; Caron, J.; Li, Fengling; Uren, A. G.; Snyder, J. P.; Vedadi, M.; Fuchter, M. J.*; Brown, R.* Clin. Epigenetics 2015, 7:84  DOI

"Dual Wavelength Asymmetric Photochemical Synthesis with Circularly Polarized Light" Richardson, R. D.; Baud, M. G. J.; Weston, C. E.; Rzepa, H. S.; Kuimova, M. K.*; Fuchter, M. J.* Chem. Sci. 2015, 6, 3853. DOI

"Design, synthesis and initial characterisation of a radiolabelled [18F]pyrimidoindolone probe for detecting activated caspase-3/7" Udemba, A.; Smith, G.; Nguyen, Q. -D.; Kaliszczak, M.; Carroll, L. S.; Fortt, R.; Fuchter, M. J.; Aboagye, E. O.* Org. Biomol. Chem. 2015, 13, 5418. DOI

"Chiroptical studies on brevianamide B: Vibrational and Electronic Circular Dichroism confronted" Bultinck, P.; Cherblanc, F. L.; Fuchter, M. J.*; Herrebout, W. A.; Lo, Y. –L.; Rzepa, H. S.*; Siligardi, G.; Weimar, M. J. Org. Chem. 2015, 80, 3359. DOI

"Histone methyltransferase inhibitors: orally bioavailable, fast acting molecules with activity against different human malaria species" Malmquist, N. A.*; Sundriyal, S.; Caron, J.; Chen, P.; Witkowski, B.; Menard, D.; Suwanarusk, R.; Renia, L.; Nosten, F.; Jiménez-Díaz, M. B.; Angulo-Barturen, I.; Martínez, M. S.; Ferrer, S.; Sanz, L. M.; Gamo, F. J.; Wittlin, S.; Duffy, S.; Avery, V. M.; Ruecker, A.; Delves, M. J.; Sinden, R. E.; Fuchter, M. J.; Scherf, A.* Antimicrob. Agents Chemother. 2015, 59, 950. DOI

"The Discovery of a Highly Selective 5,6,7,8- Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson’s Disease Model" Di Fruscia, P.; Zacharioudakis, E.; Liu, C.; Moniot, S.; Laohasinnarong, S.; Khongkow, M.; Harrison, I. F.; Koltsida, K.; Reynolds, C. R.; Schmidtkunz, K.; Jung, M.; Chapman, K. L.; Steegborn, C.; Dexter, D. T.; Sternberg, M. J. E.; Lam, E. W.-F.; Fuchter, M. J.* ChemMedChem 2015, 10, 69. DOI

2014

"Non-Metal Catalysed Hydrogenation of Carbonyl Compounds" Scott, D. J.; Fuchter, M. J.; Ashley, A. E.* J. Am. Chem. Soc. 2014, 136, 15813. DOI (Highlighted in Chemical and Engineering news DOI)

"Identification of 2,4-Diamino-6,7-dimethoxyquinoline derivatives as G9a Inhibitors" Srimongkolpithak, N.; Sundriyal, S.; Lu, F.; Vedadi, M.; Fuchter, M. J.* Med. Chem. Commun. 2014, 5, 1821. DOI - Invited Submission - Epigenetics special issue, cover article

"Metal-Free Hydrogenation Catalyzed by an Air-Stable Borane: Use of Solvent as a Frustrated Lewis Base" Scott, D. J.; Fuchter, M. J.; Ashley, A. E.* Angew. Chem. Int. Ed 2014, 53, 10218. DOI (Angew. Hot paper)

"Arylazopyrazoles: Azoheteroarene photoswitches offering quantitative isomerization and long thermal half-lives" Weston, C. E.; Richardson, R. D.; Haycock, P. R.; White, A. J. P.; Fuchter, M. J.* J. Am. Chem. Soc. 2014, 136, 11878. DOI

"Calcium-mediated stereoselective reduction of α,β-epoxy ketones"  Forkel, N. V.; Henderson, D. A.; Fuchter, M. J.* Tetrahedron Lett. 2014, 55, 5511. DOI

"Development of Diaminoquinazoline Histone Lysine Methyltransferase Inhibitors as Potent Blood-Stage Antimalarial Compounds" Sundriyal, S.; Malmquist, N. A.; Caron, J.; Blundell, S.; Liu, F.; Chen, X.; Srimongkolpithak, N.; Jin, J.; Charman, S. A.; Scherf, A.; Fuchter, M. J.* ChemMedChem 2014, 9, 2360. DOI

"Kinetic method for the large-scale analysis of the binding mechanism of histone deacetylase inhibitors" Meyners,C.; Baud, M. G. J.; Fuchter, M. J.; Meyer-Almes, F. -J.* Anal. Biochem. 2014, 460, 39. DOI

"PROFILE: Early Excellence in Physical Organic Chemistry" Fuchter, M. J. J. Phys. Org. Chem. 2014, 27, 545. DOI - Investigator highlight of M. J. Fuchter

"Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures" Dembélé, L.; Franetich, J. –F.; Lorthiois, A.; Gego, A.; Zeeman, A. M.; Kocken, C. H. M.; Le Grand, R.; Dereuddre-Bosquet, N.van Gemert, G. –J.; Sauerwein, R.; Vaillant, J. –C.; Hannoun, L.; Fuchter, M. J.; Diagana, T.; Malmquist, N. A.; Scherf, A.; Snounou, G.*; Mazier, D. Nature Med. 2014, 20, 307. DOI (Highlighted in Nature Medicine DOI)

"Gold(I) mediated rearrangement of [7]-helicene to give a benzo[cd]pyrenium cation embedded in a chiral framework" Berger, R. J. F.; Fuchter, M. J.*;
 Krossing, I.; Rzepa, H. S.; Schaefer, J.; Scherer, H. Chem. Commun. 2014, 50, 5251. DOI - Invited Submission - 2014 Emerging Investigators issue

"Thermodynamics of ligand binding to histone deacetylase like amidohydrolase from Bordetella/Alcaligenes" Meyners, C.; Baud, M. G. J.; Fuchter, M. J.; Meyer-Almes, F. -J.* J. Mol. Recognit. 2014, 27, 160. DOI

2013

"Mechanistic and chiroptical studies on the desulfurization of epidithiodioxopiperazines reveal universal retention of configuration at the bridgehead carbon atoms." Cherblanc, F. L.; Lo, Y. -P.; Herrebout, W.; Bultinck, P.; Rzepa, H. S.*; Fuchter, M. J.* J. Org. Chem. 2013, 78, 11646. DOI

"On the histone lysine methyltransferase activity of fungal metabolite chaetocin" Cherblanc, F. L.; Chapman, K.; Reid, J.; Borg, A.; Sundriyal, S.; Alcazar-Fuoli, L.; Bignell, E.; Demetriades, M.; Schofield, C. J.; Dimaggio, P.; Brown, R.; Fuchter, M. J.*J. Med. Chem. 2013, 56, 8616. DOI

"Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance." Kaliszczak, M.; Patel, H.; Kroll, S. H.; Carroll, L.; Smith, G.; Delaney, S.; Heathcote, D. A.; Bondke, A.; Fuchter, M. J.; Coombes, R. C.; Barrett, A. G. M.; Ali, S.; Aboagye, E. O.* Br. J. Cancer 2013, 109, 2356. DOI

"ortho-Substituted 1,8-Diarylnaphthalenes: Conformational Thermodynamics and Kinetics" Judge, D.; Haycock, P.; Richardson, R.; Fuchter, M. J.* Synlett 2013, 24, 2365. DOI - Invited Submission - 2013 Young Investigator Workshop EuCheMS

"Circularly polarized light detection by a chiral organic semiconductor transistor" Yang, Y.; Correa da Costa, R.; Fuchter, M. J.*; Campbell, A. J.* Nature Photon. 2013, 7, 634. DOI (Highlighted in a College press release and associated video)

"Induction of Circularly Polarized Electroluminescence from an Achiral Light Emitting Polymer via a Chiral Small Molecule Dopant" Yang, Y.; Correa da Costa, R.; Smilgies, D. –M.; Campbell, A. J.*; Fuchter, M. J.* Adv. Mater. 2013, 25, 2624. DOI (Highlighted in a College press release and associated video)

"A Scalable and Expedient Route to 1-Aza[6]helicene Derivatives and Its Subsequent Application to a Chiral-Relay Asymmetric Strategy" Weimar, M.; Correa da Costa, R.; Lee, F. –H.; Fuchter, M. J.* Org. Lett. 2013, 15, 1706. DOI

"Stoichiometric C-H arylation of tricarbonyl(arene)-chromium complexes bearing pyridine directing groups" Fuchter, M. J.*; Judge, D. K.; Weimar, M.; White, A. J. P. Dalton Trans. 2013, 42, 5615. DOI

"Perspectives on Natural Product Epigenetic Modulators in Chemical Biology and Medicine" Cherblanc, F. ; Davidson, R.; Di Fruscia, P.; Srimongkolpithak, N.; Fuchter, M. J.* Nat. Prod. Rep. 2013, 30, 605.DOI - cover article (Amongst the top ten accessed articles from the online version of Natural Product Reports during the 2nd quarter of 2013 {April - June})

"Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases" Cherblanc, F.; Chapman, K. L.; Brown, R,; Fuchter, M. J.* Nature Chem. Biol. 2013, 9, 136. DOI

"Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors" Baud, M. G. J.; Leiser, T.; Petrucci, V.; Gunaratnam, M.; Neidle, S.; Meyer-Almes, F. -J.; Fuchter, M. J.* Beilstein J. Org. Chem. 2013, 9, 81. DOI - Invited Submission - Synthetic probes for the study of biological function themed issue

"Highly Ligand Efficient and Selective N-2-(Thioethyl)picolinamide Histone Deacetylase Inhibitors Inspired by the Natural Product Psammaplin A" Baud, M. G. J.; Haus, P.; Leiser, T.; Meyer-Almes, F. -J.; Fuchter, M. J.* ChemMedChem, 2013, 8, 149. DOI

"Synthesis of sterically encumbered C10-arylated benzo[h]quinolines using ortho-substituted aryl boronic acids" Weimar, M.; Fuchter, M. J.* Org. Biomol. Chem.. 2013, 11, 31. DOI

2012

"Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum" Malmquist, N. A.; Moss, T. A.; Mecheri, S.; Scherf, A.*; Fuchter, M. J.* P. Natl. Acad. Sci. USA 2012, 109, 16708. DOI (Highlighted in Nature Reviews Microbiology DOI)

"Lanthanide replacement in organic synthesis: Luche-type reduction of α,β-unsaturated ketones in the presence of calcium triflate" Forkel, N. V.; Henderson, D. A.; Fuchter, M. J.* Green Chem. 2012, 14, 2129. DOI -cover article

"[7]-Helicene: a chiral molecular tweezer for silver(I) salts" Fuchter, M. J.*; Schaefer, J.; Judge, D. K.; Wardzinsk,i B.; Weimar, M.; Krossing, I. Dalton Trans. 2012, 41, 8238. DOI

"Current limitations and future opportunities for epigenetic therapies" Cherblanc, F.; Chapman-Rothe, N.; Brown, R.*; Fuchter, M. J. Future Med. Chem. 2012, 4, 425. DOI

"The Discovery of Novel 10,11-Dihydro-5H-dibenz[b,f]azepine SIRT2 Inhibitors" Di Fruscia, P.;Laohasinnarong, S.; Khongkow, M.; Ho, K.;K.; Kroll, S. B.; Islam, S. A.; Sternberg, M. J. E.; Schmidtkunz, K.; Jung, M.; Lam, E. W.-F.; Fuchter, M. J.* Med. Chem. Commun. 2012, 3, 373. DOI (Amongst the top ten accessed articles from the online version of MedChemComm in January 2012)

"Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A Against its Epigenetic Targets" Baud, M. G. J.; Leiser, T.; Haus, P.; Samlal, S.; Wong, A. C.; Wood, R. J.; Petrucci, V.;Gunaratnam, M.; Hughes, S. M.; Buluwela, L.; Turlais, F.; Neidle, S.; Meyer-Almes, F. J.; White, A. J. P.; Fuchter, M. J.* J. Med Chem. 2012, 55, 1731. DOI

"An Unusual Oxidative Rearrangement of [7]-Helicene" Fuchter, M. J.*; Weimar, M.; Yang, X.; Judge, D.K.; White, A. J. P. Tetrahedron Lett. 2012, 53,11 08 . DOI

"The Design and Synthesis of IBiox N-Heterocyclic Carbene Ligands Derived from Substituted Amino-Indanols" Levy, J. -N.; Latham, C.; Roisin, L.; Kandziora, N.; Di Fruscia, P.; White, A. J. P.; Woodward, S.; Fuchter, M. J.* Org. Biomol. Chem. 2012, 10, 512. DOI

2011

"On the Determination of the Stereochemistry of Semisynthetic Natural Product Analogues using Chiroptical Spectroscopy: Desulfurization of Epidithiodioxopiperazine Fungal Metabolites" Cherblanc, F.; Lo, Y.-P.; De Gussem, E.; Alcazar-Fuoli , L.; Bignell, E.; He, Y.; Chapman-Rothe, N.; Bultinck, P.; Herrebout, W. A.; Brown, R.; Rzepa H. S.; Fuchter, M. J.* Chem. Eur. J. 2011, 17, 11868. DOI

"On the Function of the Internal Cavity of Histone Deacetylase Protein 8: R37, a Crucial Residue for Catalytic Activity" Haider, S.; Joseph, C.; Neidle, S.; Fierke, C. A.; Fuchter, M. J.* Bioorg. Med. Chem. Lett. 2011, 2129. DOI

"New synthetic strategies towards Psammaplin A, access to natural product analogues" Baud, M. G. J.; Leiser, T.; Meyer-Almes, F. -J.; Fuchter, M. J.* Org. Biomol. Chem. 2011, 9, 659. DOI (Highlighted in an RSC blog)

2010

"BS-194, a potent inhibitor of cyclin-dependent protein kinases 1, 2 and 9, demonstrates anti-tumor effects in human tumor xenografts following oral administration" Heathcote, D. A.; Patel, P.; Kroll, S. H. B.; Periyasamy, M.; Alikian, M.; Kanneganti, S.; Jogalekar, A. S.; Scheiper, B.; Brackow, J. Siwicka, A.; Fuchter, M. J.; Snyder, J. P.; Liotta, D. C.; Aboagye, E. O.; Coombes, R. C.; Barrett, A. G. M.; Ali, S.* J. Med Chem. 2010, 53, 8508. DOI

"N-Heterocyclic Carbene Mediated Activation of Tetravalent Silicon Compounds: A Critical Evaluation" Fuchter, M. J.* Chem. Eur. J. 2010, 16, 12286. DOI

"SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and -2" Peck, B.; Chen, C. –Y.; Ho K. K.; Di Fruscia, P.; Myatt, S. S.; Coombe s, R. C.; Fuchter, M. J.; Hsiao, C. –D.; Lam, E.* Mol. Cancer Ther. 2010, 9, 844. DOI (One of the most cited articles in Molecular Cancer Therapeutics in 2010)

"Isoxazolidine Martinelline analogs via intramolecular 1,3-Dipolar Cycloaddition Reactions of Nitrones" Saubern, S.*; Macdonald, J. M.; Ryan, J. H.; Woodgate, R. C. J.; Louie, T. S.; Fuchter, M. J.; Holmes, A. B. Tetrahedron 2010, 66, 2761. DOI

2009

"Push-Pull Tropylium-Fused Aminoporphyrazine" Ruggiero, A.; Fuchter, M. J.; Kokas, O. J.; Negru, M.; White, A. J. P.; Haycock, P. R.; Clays, K.; Hoffman, B. M.; Barrett, A. G. M.* Tetrahedron, 2009, 65, 9690. DOI

"Serendipitous Synthesis of Trimetallic Porphyrazine Triads" Goslinski, T.; Zhong, C.; Fuchter, M. J.; White, A. J. P.; Barrett, A. G. M.*; Hoffman, B. M.* Tetrahedron Lett. 2009, 50, 5178. DOI

"The development of a highly selective inhibitor of cyclin-dependent kinase 7 (CDK7) which demonstrates anti-tumor activity" Ali, S.*; Heathcote, D. A.; Kroll, S. H. B.; Jogalekar, A. S.; Scheiper, B.; Patel, H.; Brackow, J.; Siwicka, A. Fuchter, M. J. Periyasamy, M.; Tolhurst, R. S.; Kanneganti, S. K.; Snyder, J. P.; Liotta, D. C.; Aboagye, E. O.; Barrett, A. G. M.; Coombes, R. C. Cancer Res. 2009, 69, 6208. DOI

2008

Commentary: "Constrained Analogues of Procaine as Novel Small Molecule Inhibitors of DNA Methyltransferase-I" Fuchter, M. J.* Chemtracts: Org. Chem. 2008, 21, 161.

"One-Pot Formation of Allylic Chlorides from Carbonyl Derivatives" Fuchter, M. J.*; Levy, J. N. Org. Lett. 2008, 10, 4919. DOI

"Diaryl Ether Synthesis in Supercritical Carbon Dioxide in Batch and Continuous Flow Mode" Lee, J. –K.; Fuchter, M. J.; Williamson, R. M.; Leeke, G. A.; Bush, E. J.; McConvey, I. F.; Saubern, S.; Ryan, J. H.; Holmes, A. B.* Chem. Commun. 2008, 4780. DOI

"Clean, Efficient Synthesis of O-Silylcarbamates and Ureas in Supercritical Carbon Dioxide" Fuchter, M. J.; Smith, C. J.; Tsang, M. W. –S.; Boyer, A.; Saubern, S.; Ryan, J. H.; Holmes, A. B.* Chem. Commun.. 2008, 2152. DOI

"Porphyrazines: Designer Macrocycles via Peripheral Substituent Change" Fuchter, M. J.; Zhong, C.; Zong, H.; Hoffman, B. M.; Barrett, A. G. M.* Aust. J. Chem. 2008, 61, 235. DOI -Invited Research Front Review Submission

2007

"Multi-gram Synthesis of a Water Soluble Porphyrazine and derived seco-Porphyrazine Labeling Agents" Guinchard, X.; Fuchter, M. J.; Ruggiero, A.; Duckworth, B.; Barrett, A. G. M.*; Hoffman, B. M.* Org. Lett. 2007, 9, 5291. DOI

2006

"Porphyrazines as Molecular Scaffolds: Flexible Syntheses of Novel Multimetallic Complexes" Goslinski, T.; Zhong, C.; Fuchter, M. J.; White, A. J. P.; Barrett, A. G. M.*; Hoffman, B. M.* Inorg. Chem. 2006, 45, 3686. DOI

"ROMPsphere-Supported seco-Porphyrazines: Efficient and Recyclable Photo-Oxygenation Catalysts" Fuchter, M. J.; Hoffman, B. M.*; Barrett, A. G. M.* J. Org. Chem. 2006, 71, 724. DOI

2005

"ROM Polymerization-Capture-Release. Application to the Synthesis of Unsymmetrical Porphyrazinedithiols and Peripherally Metalated Derivatives" Fuchter, M. J.; Hoffman, B. M.*; Barrett, A. G. M.* J. Org. Chem. 2005, 70, 5086. DOI

"Synthesis of Porphyrazine-Octaamine, Hexamine and Diamine Derivatives" Fuchter, M. J.; Beall, L. S.; Baum, S. M.; Montalban, A. G.; Sakellariou, E. G.; Mani, N. S.; Miller, T.; White, A. J. P.; Williams, D. J.; Barrett, A. G. M.*; Hoffman, B. M.* Tetrahedro n, 2005, 61, 6115 . DO I

"ROM Polymerization-Capture-Release Strategy for the Chromatography-Free Synthesis of Novel Unsymmetrical Porphyrazines" Fuchter, M. J.; Vesper, B. J.; Murphy, K. A.; Collins, H. A.; Phillips, D.; Hoffman, B. M.*; Barrett, A. G. M.* J. Org. Chem. 2005, 70, 2793. DOI

2003

"Regiochemical observations on the lithiation of 1,2,4-trichlorobenzene and reaction with DMF and oxamide electrophiles in THF" Burton, A. J.*; Cardwell, K. S.; Fuchter, M. J.; Lindvall, M. K.; Patel, R.; Packham, T. W.; Prodger, J. C.; Schilling, M. B.; Walker, M. D. Tetrahedron Letters, 2003, 44, 5653. DOI