During infection, bacteria face the twin threats of antibiotics and the host immune system. Resistance to one sometimes confers resistance to the other.
Researchers in this field include:
- Dr Luke Allsopp: Bacterial secretion systems and biofilms factors
- Professor Darius Armstrong-James: Basis of fungal persistence and adaptation in the host, phenotypic microarray facility
- Dr Thomas Clarke: Microbiota influence on host responses to bacterial infection and vaccination
- Dr Abigail Clements: The role of bacterial surface structures in pathogenesis
- Professor Marc Dionne: How do host defences promote acquisition of antimicrobial resistance?
- Dr Andy Edwards: Bacterial DNA repair systems
- Dr Ana Eulalio: Role of microRNAs and the impact of bacterial intracellular lifestyles on pathogenesis
- Dr Harry Low: Membrane remodelling processes to evade the immune system and develop resistance
- Dr Alex McCarthy: Pathogens exploitation of immunomodulatory receptors
- Dr Brian Robertson: Host pathogen-interactions underlying tuberculosis infection
- Dr Avinash Shenoy: Inflammasome evasion by enteric bacterial pathogens
- Dr Matthew Siggins: Bacterial virulence factors in invasion
- Dr Teresa Thurston: Pathogen inhibition of innate immune signaling
- Dr Calvin Tiengwe: Host-pathogen interactions for trypanosomiasis
