CDT React - Student Publications

Aatikah Majid - Cohort 1 (Intake 2019)

"Radiolabelling Pt-based quadruplex DNA binders via click chemistry"

• Lo, R., Majid, A., Fruhwirth, G. O., & Vilar, R., 2022. Bioorganic & Medicinal Chemistry, 76, 117097. doi.org/10.1016/j.bmc.2022.117097

Hannah Broderick - Cohort 1 (Intake 2019)

"Visible Light Photoredox-Catalyzed Decarboxylative Alkylation of 3-Aryl-Oxetanes and Azetidines via Benzylic Tertiary Radicals and Implications of Benzylic Radical Stability"

• Dubois, M.A., Rojas, J.J., Sterling, A.J., Broderick, H.C., Smith, M.A., White, A.J., Miller, P.W., Choi, C., Mousseau, J.J., Duarte, F. and Bull, J.A., J. Org. Chem., 2023, DOI: 10.1021/acs.joc.3c00083

Joshua Davies - Cohort 1 (Intake 2019)

"Silicon compounds as stoichiometric coupling reagents for direct amidation"

• J. J. Davies, D. C. Braddock, P. D. Lickiss, Org. Biomol. Chem., 2021, 19, 6746-6760, doi.org/10.1039/D1OB01003D

"Methyltrimethoxysilane (MTM) as a Reagent for Direct Amidation of Carboxylic Acids"

• Braddock, D.C., Davies, J.J. and Lickiss, P.D., 2022. Methyltrimethoxysilane (MTM) as a Reagent for Direct Amidation of Carboxylic Acids. Organic letters, 24(5), pp.1175-1179.

Sean McCarthy - Cohort 1 (Intake 2019)

"Strategies for sustainable palladium catalysis"

• S. McCarthy, D. C. Braddock, J. D. E. T. Wilton-Ely, Coordin. Chem. Rev., 2021, 442, DOI: 10.1016/j.ccr.2021.213925.

"From waste to green applications: The use of recovered gold and palladium in catalysis”

• S. McCarthy, A. L. W. Jie, D. C. Braddock, A. Serpe, J. D. E. T. Wilton-Ely, Molecules, 2021, 26, DOI: 10.3390/molecules26175217.

"Homogeneous Gold Catalysis Using Complexes Recovered from Waste Electronic Equipment"

• McCarthy, S., Desaunay, O., Jie, A.L.W., Hassatzky, M., White, A.J., Deplano, P., Braddock, D.C., Serpe, A. and Wilton-Ely, J.D., ACS Sustainable Chemistry & Engineering, 2022, 10(48), doi.org/10.1021/acssuschemeng.2c04092

“Palladium complexes derived from waste as catalysts for C-H functionalisation and C-N bond formation”

• A. Jantan, G. Ekart, S. McCarthy, A. J. P. White, D. C. Braddock, A. Serpe, J. D. E. T. Wilton-Ely* Catalysts, 2024, 14, 295 [DOI: 10.3390/catal14050295]

Linden Schrecker - Cohort 1 (Intake 2019)

"Discovery of unexpectedly complex reaction pathways for the Knorr pyrazole synthesis via transient flow"

• L. Schrecker, J. Dickhaut, Christian Holtze, P. Staehle, M. Vranceanu, K. Hellgardt, K. K. Hii, React. Chem. Eng. 2023, 8, 41-46. DOI: 10.1039/D2RE00271J. 

"An efficient multiparameter method for the collection of chemical reaction data via ‘one-pot’ transient flow"

• L. Schrecker, J. Dickhaut, C. Holtze, P. Staehle, A. Weija, K. Hellgardt, K. K. Hii, React. Chem. Eng. 2023, 8, 3196-3202. DOI: 10.1039/D3RE00439B. 

“A Comparative Study of Transient Flow Rate Steps and Ramps for the Efficient Collection of Kinetic Data”

• Schrecker, J. Dickhaut, C. Holtze, P. Staehle, M. Vranceanu, A. Wieja, K. Hellgardt and K. K. Hii,* React. Chem. Eng, 2024, 9, 1077-1086. DOI: 10.1039/d3re00696d.

Filip Horvarth-Gerber - Cohort 1 (Intake 2019)

"Mass transport of Diazomethane across Teflon AF2400 membrane for scale-up development”

• Horvath-Gerber, K. K. Hii, C. Holtze, E. J. C. Deublein, K. Hellgardt, Org. Process Res. Dev. 2023, 27, 899-909. DOI: 10.1021/acs.oprd.3c00023.

Ben Lancaster - Cohort 1 (Intake 2019)

"Surmounting Byproduct Inhibition in an Intermolecular Catalytic Asymmetric Alkene Bromoesterification Reaction as Revealed by Kinetic Profiling”

• Braddock, D. C., Lancaster, B. M., Tighe, C. J., & White, A. The Journal of Organic Chemistry, 2023, DOI: https://doi.org/10.1021/acs.joc.3c00672

Matthew Takle - Cohort 1 (Intake 2019)

"A Flash Thermal Racemization Protocol for the Chemoenzymatic Dynamic Kinetic Resolution and Stereoinversion of Chiral Amines”

• Takle, M. J., Deadman, B. J., Hellgardt, K., Dickhaut, J., Wieja, A., & Hii, K. K. M. ACS Catalysis, 13(16), 10541-10546, 2023, DOI: https://doi.org/10.1021/acscatal.3c02859

Annabel Basford - Cohort 2 (Intake 2020)

"Streamlining the Automated Discovery of Porous Organic Cages"

• Basford, A., Bennett S., Xiao M., Turcani L., Allen J., Jelfs K., Greenaway R., ChemRxiv, November 2023

Sarah Patrick - Cohort 2 (Intake 2020)

"A Continuous Flow Process for the Defluorosilylation of HFC-23 and HFO-1234yf"

• S. L. Patrick, J. A. Bull, P. W. Miller, M. R. Crimmin, Org. Lett. 2024, 26, 40, 8605–8609

Harriet Judah - Cohort 2 (Intake 2020) [Blog]

"Chemical recycling: where one plastic’s trash is another plastic’s treasure"

Hamish Trowell - Cohort 2 (Intake 2020) 

Incorporating Photoresponses into Porous Liquids

• Dr. Michael C. Brand, Hamish G. Trowell, Prof. Matthew J. Fuchter and Dr. Rebecca L. Greenaway, Chem. Eur. J., 2024, 30, e202303593, DOI: 10.1002/chem.202303593.

Photoresponsive Organic Cages—Computationally Inspired Discovery of Azobenzene-Derived Organic Cages

• Michael C. Brand^#, Hamish G. Trowell^#, James T. Pegg, Jake L. Greenfield, Magdalena Odaybat, Marc A. Little, Peter R. Haycock, Gokay Avci, Nicola Rankin, Matthew J. Fuchter, Kim E. Jelfs, Andrew I. Cooper and Rebecca L. Greenaway, JACS, 2024, DOI: 10.1021/jacs.4c10217.

Miguel Angel de Carvalho Servia - Cohort 3 (Intake 2021)

"The Automated Discovery of Kinetic Rate Models--Methodological Frameworks"

• Ángel de Carvalho Servia, M., Orson Sandoval, I., Hellgardt, K., Hii, K. K., Zhang, D. and del Rio Chanona, E.A., Digital Discovery, 2024 https://doi.org/10.1039/D3DD00212H

Friedrich Hastedt - Cohort 4 (Intake 2022)

“Investigating the Reliability and Interpretability of Machine Learning Frameworks for Chemical Retrosynthesis”

• Hastedt, R. M. Bailey, K. Hellgardt, S. N. Yaliraki, E. A. del Rio Chanona, and D. Zhang, Digital Discovery, 2024, 3, 1194-1212, DOI: 10.1039/D4DD00007