Theme 2: Learning from heart disease patients
Molecular and Genetic Determinants of Adverse Remodelling
Theme 2 aims to identify the environmental, genetic and cellular drivers of how the heart adapts during the transition from health to disease. The program brings together a diverse team of scientists and clinicians working across scales to identify treatable mechanisms of cardiac remodelling. This work bridges population-level discovery science, based on genomics and imaging, with multi-omic analysis of human cells and tissues.
Theme leads
Declan O'Regan
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Declan O'Regan
Clinical
Michela Noseda
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Michela Noseda
Translational
Co-investigators
Ed Tate
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Ed Tate
Fu Siong Ng
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Fu Siong Ng
James Ware
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James Ware
Julia Gorelik
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Julia Gorelik
Manuel Mayr
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Manuel Mayr
Key investigators
Andreia Bernardo
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Andreia Bernardo
Rasheda Chowdhury
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Rasheda Chowdhury
Upasana (Paz) Tayal
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Upasana (Paz) Tayal
General enquiries
BHF Centre of Research Excellence
ICTEM Building
Hammersmith Campus
Du Cane Road
London W12 0NN
BHF Centre Manager
Mrs Jaya Rajamanie
j.rajamanie@imperial.ac.uk
Follow us on X
@BHFCoREImperial