Learning from heart disease patients

Theme 2: Learning from heart disease patients

Molecular and Genetic Determinants of Adverse Remodelling

Theme 2 aims to identify the environmental, genetic and cellular drivers of how the heart adapts during the transition from health to disease. The program brings together a diverse team of scientists and clinicians working across scales to identify treatable mechanisms of cardiac remodelling. This work bridges population-level discovery science, based on genomics and imaging, with multi-omic analysis of human cells and tissues.