@inproceedings{Cavuto:2019:10.1109/NER.2019.8717128,
author = {Cavuto, ML and Constandinou, TG},
doi = {10.1109/NER.2019.8717128},
pages = {665--669},
publisher = {IEEE},
title = {Investigation of insertion method to achieve chronic recording stability of a semi-rigid implantable neural probe},
url = {http://dx.doi.org/10.1109/NER.2019.8717128},
year = {2019}
}

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TY  - CPAPER
AB  - Brain machine interfaces notoriously face difficulties in achieving long term implanted recording stability. It has been shown that damage and inflammation, caused during insertion by electrodes that are too large and stiff, provoke a sustained inflammatory tissue response. This is commonly referred to as the foreign body response, resulting in encapsulation and thus increased electrode impedance over time. Accordingly, neural interfaces with ever smaller and more flexible electrodes are continually in development, but unfortunately face challenges of their own, first and foremost of which is buckling and bending during insertion. This work presents the development of a prototype insertion method, comprising an insertion device and novel probe architecture, that promotes straight insertion without buckling, while simultaneously minimizing the insertion force for multi-microwire electrode probes. When compared against insertion of probes with unsupported free electrodes, the prototype method achieved significantly straighter electrode insertion, resulting in both a smaller distance between electrode recording tips and a greater average insertion depth. While achieving less straight insertion than probes with sucrose coated electrodes, a common technique for promoting reliable insertion without buckling, the tested method was able to maintain significantly lower insertion forces.
AU  - Cavuto,ML
AU  - Constandinou,TG
DO  - 10.1109/NER.2019.8717128
EP  - 669
PB  - IEEE
PY  - 2019///
SN  - 1948-3546
SP  - 665
TI  - Investigation of insertion method to achieve chronic recording stability of a semi-rigid implantable neural probe
UR  - http://dx.doi.org/10.1109/NER.2019.8717128
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000469933200162&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/72536
ER  - 

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