In this section
@article{Phillips:2015:10.1080/23335432.2015.1017609,
author = {Phillips, ATM and Villette, CC and Modenese, L},
doi = {10.1080/23335432.2015.1017609},
journal = {International Biomechanics},
pages = {43--61},
title = {Femoral bone mesoscale structural architecture prediction using musculoskeletal and finite element modelling},
url = {http://dx.doi.org/10.1080/23335432.2015.1017609},
volume = {2},
year = {2015}
}
TY - JOUR
AB - Through much of the anatomical and clinical literature bone is studied with a focus on its structural architecture, while it is rare for bone to be modelled using a structural mechanics as opposed to a continuum mechanics approach in the engineering literature. A novel mesoscale structural model of the femur is presented in which truss and shell elements are used to represent trabecular and cortical bone, respectively. Structural optimisation using a strain-based bone adaptation algorithm is incorporated within a musculoskeletal and finite element modelling framework to predict the structure of the femur subjected to two loading scenarios; a single load case corresponding to the frame of maximum hip joint contact force during walking and a full loading regime consisting of multiple load cases from five activities of daily living. The use of the full loading regime compared to the single load case has a profound influence on the predicted trabecular and cortical structure throughout the femur, with dramatic volume increases in the femoral shaft and the distal femur, and regional increases at the femoral neck and greater trochanter in the proximal femur. The mesoscale structural model subjected to the full loading regime shows agreement with the observed structural architecture of the femur while the structural approach has potential application in bone fracture prediction, prevention and treatment. The mesoscale structural approach achieves the synergistic goals of computational efficiency similar to a macroscale continuum approach and a resolution nearing that of a microscale continuum approach.
AU - Phillips,ATM
AU - Villette,CC
AU - Modenese,L
DO - 10.1080/23335432.2015.1017609
EP - 61
PY - 2015///
SN - 2333-5432
SP - 43
TI - Femoral bone mesoscale structural architecture prediction using musculoskeletal and finite element modelling
T2 - International Biomechanics
UR - http://dx.doi.org/10.1080/23335432.2015.1017609
UR - http://www.tandfonline.com/doi/full/10.1080/23335432.2015.1017609
UR - https://www.tandfonline.com/doi/full/10.1080/23335432.2015.1017609
UR - http://hdl.handle.net/10044/1/21510
VL - 2
ER -