@article{Wilkinson:2016:10.1038/nm.4161,
author = {Wilkinson, RJ and Esmail, H and Lesosky, M and Lai, RP and Wilkinson, KA and Graham, CM and Coussens, AK and Oni, T and Warwick, J and Said-Hartley, Q and Koegenelburg, CF and Walzl, G and Flynn, JL and young, DB and Barry, CE and O'Garra, A},
doi = {10.1038/nm.4161},
journal = {Nature Medicine},
title = {[18F]-FDG PET/CT characterisation of progressive HIV-associated tuberculosis},
url = {http://dx.doi.org/10.1038/nm.4161},
year = {2016}
}

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TY  - JOUR
AB  - Tuberculosis is classically divided into states of latent infection and active disease. Usingcombined positron emission and computed tomography in 35 asymptomatic, antiretroviraltherapy naïve, HIV-1 infected adults with latent tuberculosis, we identified ten individualswith pulmonary abnormalities suggestive of subclinical, active disease who weresignificantly more likely to progress to clinical disease. Our findings challenge theconventional two-state paradigm and may aid future identification of biomarkers predictiveof progression.
AU  - Wilkinson,RJ
AU  - Esmail,H
AU  - Lesosky,M
AU  - Lai,RP
AU  - Wilkinson,KA
AU  - Graham,CM
AU  - Coussens,AK
AU  - Oni,T
AU  - Warwick,J
AU  - Said-Hartley,Q
AU  - Koegenelburg,CF
AU  - Walzl,G
AU  - Flynn,JL
AU  - young,DB
AU  - Barry,CE
AU  - O'Garra,A
DO  - 10.1038/nm.4161
PY  - 2016///
SN  - 1546-170X
TI  - [18F]-FDG PET/CT characterisation of progressive HIV-associated tuberculosis
T2  - Nature Medicine
UR  - http://dx.doi.org/10.1038/nm.4161
UR  - http://hdl.handle.net/10044/1/37409
ER  - 

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