@article{Streatfield:2014:10.3402/gha.v7.25370,
author = {Streatfield, PK and Khan, WA and Bhuiya, A and Hanifi, SMA and Alam, N and Millogo, O and Sié, A and Zabré, P and Rossier, C and Soura, AB and Bonfoh, B and Kone, S and Ngoran, EK and Utzinger, J and Abera, SF and Melaku, YA and Weldearegawi, B and Gomez, P and Jasseh, M and Ansah, P and Azongo, D and Kondayire, F and Oduro, A and Amu, A and Gyapong, M and Kwarteng, O and Kant, S and Pandav, CS and Rai, SK and Juvekar, S and Muralidharan, V and Wahab, A and Wilopo, S and Bauni, E and Mochamah, G and Ndila, C and Williams, TN and Khagayi, S and Laserson, KF and Nyaguara, A and Van, Eijk AM and Ezeh, A and Kyobutungi, C and Wamukoya, M and Chihana, M and Crampin, A and Price, A and Delaunay, V and Diallo, A and Douillot, L and Sokhna, C and Gómez-Olivé, FX and Mee, P and Tollman, SM and Herbst, K and Mossong, J and Chuc, NTK and Arthur, SS and Sankoh, OA and Byass, P},
doi = {10.3402/gha.v7.25370},
journal = {Global Health Action},
title = {HIV/AIDS-related mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites},
url = {http://dx.doi.org/10.3402/gha.v7.25370},
volume = {7},
year = {2014}
}

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TY  - JOUR
AB  - BACKGROUND: As the HIV/AIDS pandemic has evolved over recent decades, Africa has been the most affected region, even though a large proportion of HIV/AIDS deaths have not been documented at the individual level. Systematic application of verbal autopsy (VA) methods in defined populations provides an opportunity to assess the mortality burden of the pandemic from individual data. OBJECTIVE: To present standardised comparisons of HIV/AIDS-related mortality at sites across Africa and Asia, including closely related causes of death such as pulmonary tuberculosis (PTB) and pneumonia. DESIGN: Deaths related to HIV/AIDS were extracted from individual demographic and VA data from 22 INDEPTH sites across Africa and Asia. VA data were standardised to WHO 2012 standard causes of death assigned using the InterVA-4 model. Between-site comparisons of mortality rates were standardised using the INDEPTH 2013 standard population. RESULTS: The dataset covered a total of 10,773 deaths attributed to HIV/AIDS, observed over 12,204,043 person-years. HIV/AIDS-related mortality fractions and mortality rates varied widely across Africa and Asia, with highest burdens in eastern and southern Africa, and lowest burdens in Asia. There was evidence of rapidly declining rates at the sites with the heaviest burdens. HIV/AIDS mortality was also strongly related to PTB mortality. On a country basis, there were strong similarities between HIV/AIDS mortality rates at INDEPTH sites and those derived from modelled estimates. CONCLUSIONS: Measuring HIV/AIDS-related mortality continues to be a challenging issue, all the more so as anti-retroviral treatment programmes alleviate mortality risks. The congruence between these results and other estimates adds plausibility to both approaches. These data, covering some of the highest mortality observed during the pandemic, will be an important baseline for understanding the future decline of HIV/AIDS.
AU  - Streatfield,PK
AU  - Khan,WA
AU  - Bhuiya,A
AU  - Hanifi,SMA
AU  - Alam,N
AU  - Millogo,O
AU  - Sié,A
AU  - Zabré,P
AU  - Rossier,C
AU  - Soura,AB
AU  - Bonfoh,B
AU  - Kone,S
AU  - Ngoran,EK
AU  - Utzinger,J
AU  - Abera,SF
AU  - Melaku,YA
AU  - Weldearegawi,B
AU  - Gomez,P
AU  - Jasseh,M
AU  - Ansah,P
AU  - Azongo,D
AU  - Kondayire,F
AU  - Oduro,A
AU  - Amu,A
AU  - Gyapong,M
AU  - Kwarteng,O
AU  - Kant,S
AU  - Pandav,CS
AU  - Rai,SK
AU  - Juvekar,S
AU  - Muralidharan,V
AU  - Wahab,A
AU  - Wilopo,S
AU  - Bauni,E
AU  - Mochamah,G
AU  - Ndila,C
AU  - Williams,TN
AU  - Khagayi,S
AU  - Laserson,KF
AU  - Nyaguara,A
AU  - Van,Eijk AM
AU  - Ezeh,A
AU  - Kyobutungi,C
AU  - Wamukoya,M
AU  - Chihana,M
AU  - Crampin,A
AU  - Price,A
AU  - Delaunay,V
AU  - Diallo,A
AU  - Douillot,L
AU  - Sokhna,C
AU  - Gómez-Olivé,FX
AU  - Mee,P
AU  - Tollman,SM
AU  - Herbst,K
AU  - Mossong,J
AU  - Chuc,NTK
AU  - Arthur,SS
AU  - Sankoh,OA
AU  - Byass,P
DO  - 10.3402/gha.v7.25370
PY  - 2014///
SN  - 1654-9880
TI  - HIV/AIDS-related mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites
T2  - Global Health Action
UR  - http://dx.doi.org/10.3402/gha.v7.25370
UR  - https://www.ncbi.nlm.nih.gov/pubmed/25377330
UR  - http://hdl.handle.net/10044/1/76308
VL  - 7
ER  - 

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