Patient with anaesthesiaAnaesthesia makes up the largest hospital speciality and has a huge role to play in nearly every aspect of any hospital from operating theatres to accident and emergency, to the labour ward, and to intensive care. Our research ranges from basic molecular research into mechanisms of anaesthesia to investigating the clinical impact of novel anaesthetic agents. 

Our research covers the entirety of patient’s perioperative journey and through this, we aim to deliver the greatest impact. The section has been pioneering in the development of novel technologies to facilitate the delivery of anaesthetic agents and has also made pivotal in-roads into the mechanism of action of anaesthetic agents and their wider application to other diseases (such as their protective roles in brain injury and in cancer).

Research themes:

Citation

BibTex format

@article{Zhao:2016:10.1097/ALN.0000000000001128,
author = {Zhao, H and Mitchell, S and Koumpa, S and Cui, YT and Lian, Q and Hagberg, H and Johnson, M and Takata, M and Ma, D},
doi = {10.1097/ALN.0000000000001128},
journal = {Anesthesiology},
pages = {180--192},
title = {Heme Oxygenase-1 mediates neuro-protection conferred by argon in combination with hypothermia in neonatal hypoxia-ischemia brain injury},
url = {http://dx.doi.org/10.1097/ALN.0000000000001128},
volume = {125},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Argon–hypothermia treatment reduced both neuronal death in an in vitro neuronal culture model and brain infarct size in an in vivo rat model of neonatal asphyxia. The protective effects of argon–hypothermia involve both inhibition of apoptosis and neuroinflammation mechanisms and activation of cell survival pathways.
AU  - Zhao,H
AU  - Mitchell,S
AU  - Koumpa,S
AU  - Cui,YT
AU  - Lian,Q
AU  - Hagberg,H
AU  - Johnson,M
AU  - Takata,M
AU  - Ma,D
DO  - 10.1097/ALN.0000000000001128
EP  - 192
PY  - 2016///
SN  - 1528-1175
SP  - 180
TI  - Heme Oxygenase-1 mediates neuro-protection conferred by argon in combination with hypothermia in neonatal hypoxia-ischemia brain injury
T2  - Anesthesiology
UR  - http://dx.doi.org/10.1097/ALN.0000000000001128
UR  - http://hdl.handle.net/10044/1/30175
VL  - 125
ER  -
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