Anaesthesia makes up the largest hospital speciality and has a huge role to play in nearly every aspect of any hospital from operating theatres to accident and emergency, to the labour ward, and to intensive care. Our research ranges from basic molecular research into mechanisms of anaesthesia to investigating the clinical impact of novel anaesthetic agents.
Our research covers the entirety of patient’s perioperative journey and through this, we aim to deliver the greatest impact. The section has been pioneering in the development of novel technologies to facilitate the delivery of anaesthetic agents and has also made pivotal in-roads into the mechanism of action of anaesthetic agents and their wider application to other diseases (such as their protective roles in brain injury and in cancer).
Research themes:
- Anaesthesia mechanisms and effects
- Brain and neuroprotection
- Cardiothoracic anaesthesia and transplantation
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Journal articleGhosh S, Wilson MR, Choudhury S, et al., 2005,
Effects of inhaled carbon monoxide on acute lung injury in mice
, AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, Vol: 288, Pages: L1003-L1009, ISSN: 1040-0605- Author Web Link
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- Citations: 34
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Journal articleSanders RD, Giombini M, Ma DQ, et al., 2005,
Dexmedetomidine exerts dose-dependent age-independent antinociception but age-dependent hypnosis in Fischer rats
, ANESTHESIA AND ANALGESIA, Vol: 100, Pages: 1295-1302, ISSN: 0003-2999- Author Web Link
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- Citations: 25
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Journal articleMarczin N, 2004,
Tiny wonders of tiny impurities of nitrous oxide during anaesthesia
, BRITISH JOURNAL OF ANAESTHESIA, Vol: 93, Pages: 619-623, ISSN: 0007-0912- Author Web Link
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- Citations: 2
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Journal articleMa DQ, Sanders RD, Halder S, et al., 2004,
Xenon exerts age-independent antinociception in Fischer rats
, ANESTHESIOLOGY, Vol: 100, Pages: 1313-1318, ISSN: 0003-3022- Author Web Link
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- Citations: 22
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Journal articleMarczin N, El-Habashi N, Hoare GS, et al., 2003,
Antioxidants in myocardial ischemia-reperfusion injury: therapeutic potential and basic mechanisms
, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Vol: 420, Pages: 222-236, ISSN: 0003-9861- Author Web Link
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- Citations: 132
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Journal articleSanders RD, Franks NP, Maze M, 2003,
Xenon: no stranger to anaesthesia
, BRITISH JOURNAL OF ANAESTHESIA, Vol: 91, Pages: 709-717, ISSN: 0007-0912- Author Web Link
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- Citations: 82
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Journal articleHomi HM, Yokoo N, Ma DQ, et al., 2003,
The neuroprotective effect of xenon administration during transient middle cerebral artery occlusion in mice
, ANESTHESIOLOGY, Vol: 99, Pages: 876-881, ISSN: 0003-3022- Author Web Link
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- Citations: 137
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Journal articleDickinson R, Awaiz S, Whittington MA, et al., 2003,
The effects of general anaesthetics on carbachol-evoked gamma oscillations in the rat hippocampus in vitro
, NEUROPHARMACOLOGY, Vol: 44, Pages: 864-872, ISSN: 0028-3908- Author Web Link
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- Citations: 69
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Journal articleDickinson R, de Sousa SLM, Lieb WR, et al., 2002,
Selective synaptic actions of thiopental and its enantiomers
, ANESTHESIOLOGY, Vol: 96, Pages: 884-892, ISSN: 0003-3022- Author Web Link
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- Citations: 18
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BookMarczin N, Kharitonov SA, Yacoub MH, et al., 2002,
Disease markers in exhaled breath
, New York, Basel, Publisher: Marcel Dekker, Inc, ISBN: 9780824708177
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