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Journal articleWariri O, Utazi CE, Okomo U, et al., 2025,
Multi-level determinants of timely routine childhood vaccinations in The Gambia: Findings from a nationwide analysis
, Vaccine, Vol: 43, ISSN: 0264-410XIntroduction: Achieving the ambitious goals of the Immunisation Agenda 2030 (IA2030) requires a deeper understanding of factors influencing under-vaccination, including timely vaccination. This study investigates the demand- and supply-side determinants influencing the timely uptake of key childhood vaccines scheduled throughout the first year of life in The Gambia. Methods: We used two nationally-representative datasets: the 2019–20 Gambian Demographic and Health Survey and the 2019 national immunisation facility mapping. Using Bayesian multi-level binary logistic regression models, we identified key factors significantly associated with timely vaccination for five key vaccines: birth dose of hepatitis-B (HepB0), first, second, and third doses of the pentavalent vaccine (Penta1, Penta2, Penta3), and first-dose of measles-containing vaccine (MCV1) in children aged 12–35 months. We report the adjusted Odds Ratios (aORs) and 95 % Credible Intervals (95 % CIs) in each case. Results: We found that demand-side factors, such as ethnicity, household wealth status, maternal education, maternal parity, and the duration of the household's residency in its current location, were the most common drivers of timely childhood vaccination. However, supply-side factors such as travel time to the nearest immunisation clinic, availability of cold-storage and staffing numbers in the nearest immunisation clinic were also significant determinants. Furthermore, the determinants varied across specific vaccines and the timing of doses. For example, delivery in a health facility (aOR = 1.58, 95 %CI: 1.02–2.53), living less than 30 min (aOR = 2.11, 95 %CI: 1.2–8.84) and living between 30 and 60 min (aOR = 3.68, 95 %CI: 1.1–14.99) from a fixed-immunisation clinic was associated with timely HepB0, a time-sensitive vaccine that must be administered within 24 h of birth. On the other hand, children who received Penta1 and Penta2 on time were three- to five-fold more
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Journal articleEwers RM, Cook J, Daniel OZ, et al., 2024,
New insights to be gained from a Virtual Ecosystem
, Ecological Modelling, Vol: 498, ISSN: 0304-3800The myriad interactions among individual plants, animals, microbes and their abiotic environment generate emergent phenomena that will determine the future of life on Earth. Here, we argue that holistic ecosystem models – incorporating key biological domains and feedbacks between biotic and abiotic processes and capable of predicting emergent phenomena – are required if we are to understand the functioning of complex, terrestrial ecosystems in a rapidly changing planet. We argue that holistic ecosystem models will provide a framework for integrating the many approaches used to study ecosystems, including biodiversity science, population and community ecology, soil science, biogeochemistry, hydrology and climate science. Holistic models will provide new insights into the nature and importance of feedbacks that cut across scales of space and time, and that connect ecosystem domains such as microbes with animals or above with below ground. They will allow us to critically examine the origins and maintenance of ecosystem stability, resilience and sustainability through the lens of systems theory, and provide a much-needed boost for conservation and the management of natural environments. We outline our approach to developing a holistic ecosystem model – the Virtual Ecosystem – and argue that while the construction of such complex models is obviously ambitious, it is both feasible and necessary.
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Journal articleSchroeder AK, Woodward H, Le Cornec CMA, et al., 2024,
Vehicle emission models alone are not sufficient to understand full impact of change in traffic signal timings
, Atmospheric Environment: X, Vol: 24, ISSN: 2590-1621Few studies have considered the real-world impact of changes in traffic signal timings on air pollution and pedestrian exposure with most only drawing their conclusion from vehicle emission models alone. Here, we consider two distinct cycle timings at a junction in London, UK, model the impact using a traffic microsimulation and a NOx emissions model, and compare these results with NOx and other air pollution measurements collected during a two-week field study at the junction.Our models predict that extending the cycle time leads to a 23% decrease in NOx emissions within a 15 m radius of the junction itself. When the wind direction was such that our sensors were downwind of the junction a 21% decrease in traffic and background-adjusted NOx concentrations were seen, suggesting that the intervention was successful. However, when the sensors were upwind of the junction, we observed an increase of 23% in adjusted NOx concentrations. Similar patterns were found for the other pollutants NO2, lung deposited surface area, black carbon and CO2 we measured. This indicates that meteorology was by far the greatest determinant of roadside concentrations during our two-week study period.Looking at pedestrian exposure for pedestrians waiting to cross the road, we found that their NOx exposure increased by 46% as waiting times to cross the road increased and that potential small reductions in air pollution were offset by increases in waiting times on the main road.The study demonstrates the need to go beyond assessing the impact of hyper-local traffic interventions on vehicle emissions. Real-world trials over extended periods are required to evaluate the impact of meteorology and changes to air pollution concentrations and pedestrian exposures.
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Journal articleOlivelli A, Maxence P, Xu H, et al., 2024,
Vertical transport of anthropogenic lead by reversible scavenging in the South Atlantic Ocean
, Earth and Planetary Science Letters, Vol: 646, ISSN: 0012-821XStable lead (Pb) isotopes have been regarded as tracers of ocean circulation, both in the present time and geological past. Here we present a new dataset of seawater Pb concentrations and isotope compositions for ten depth profiles from the South Atlantic Ocean (GEOTRACES cruises GA02 and GA10). By comparing Pb isotope data collected on the two cruises, and by modelling the distribution of Pb with an extended optimum multiparameter analysis, we find evidence of vertical transport of anthropogenic Pb pollution due to reversible scavenging. Surface to depth transfer of polluted Pb is aided by high suspended particulate matter loads at the Brazil – Malvinas Confluence and along ∼40°S in the South Atlantic. Overall, our findings caution the use of Pb isotope ratios as ventilation tracers in the South Atlantic and emphasize the importance of particle-seawater interaction for biogeochemical cycles.
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Journal articleLiu J, Ryu Y, Luo X, et al., 2024,
Evidence for widespread thermal acclimation of canopy photosynthesis
, Nature Plants, ISSN: 2055-026XPlants acclimate to temperature by adjusting their photosynthetic capacity over weeks to months. However, most evidence for photosynthetic acclimation derives from leaf-scale experiments. Here, we address the scarcity of evidence for canopy-scale photosynthetic acclimation by examining the correlation between maximum photosynthetic rates (Amax,2000) and growth temperature ((T_air ) ̅) across a range of concurrent temperatures and canopy foliage quantity, using data from over 200 eddy covariance sites. We detect widespread thermal acclimation of canopy-scale photosynthesis, demonstrated by enhanced Amax,2000 under higher (T_air ) ̅, across flux sites with adequate water availability. A 14-day period is identified as the most relevant time scale for acclimation across all sites, with a range of 12–25 days for different plant functional types. The mean apparent thermal acclimation rate across all ecosystems is 0.41 (-0.38–1.04 for 5th–95th percentile range) µmol m-2 s-1 C-1, with croplands showing the largest and grasslands the lowest acclimation rates. Incorporating an optimality-based prediction of leaf photosynthetic capacities into a biochemical photosynthesis model is shown to improve the representation of thermal acclimation. Our results underscore the critical need for enhanced understanding and modelling of canopy-scale photosynthetic capacity to accurately predict plant responses to warmer growing seasons.
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Journal articleZhang-Zheng H, Deng X, Aguirre-Gutierrez J, et al., 2024,
Why models underestimate West African tropical forest primary productivity
, Nature Communications, ISSN: 2041-1723 -
Journal articleAlonzo D, Tabelin CB, Dalona IM, et al., 2024,
Working with the community for the rehabilitation of legacy mines: Approaches and lessons learned from the literature
, Resources Policy, Vol: 98, ISSN: 0301-4207 -
Journal articleBlyth L, Graven H, Manning AJ, et al., 2024,
Radiocarbon as a tracer of the fossil fraction of regional carbon monoxide emissions
, Environmental Research Letters, Vol: 19Carbon monoxide (CO) is an atmospheric pollutant with a positive net warming effect on the climate. The magnitude of CO sources and the fraction of fossil vs biogenic sources are still uncertain and vary across emissions inventories. Measurements of radiocarbon (14C) in CO could potentially be used to investigate the sources of CO on a regional scale because fossil sources lack 14C and reduce the 14C/C ratio (Δ14C) of atmospheric CO more than biogenic sources. We use regional Lagrangian model simulations to investigate the utility of Δ14CO measurements for estimating the fossil fraction of CO emissions and evaluating bottom-up emissions estimates (United Kingdom Greenhouse Gas, UKGHG, and TNO Copernicus Atmosphere Monitoring Service, TNO) in London, UK. Due to the high Δ14CO in atmospheric CO from cosmogenic production, both fossil and biogenic CO emissions cause large reductions in Δ14CO regionally, with larger reductions for fossil than biogenic CO per ppb added. There is a strong seasonal variation in Δ14CO in background air and in the sensitivity of Δ14CO to fossil and biogenic emissions of CO. In the UK, the CO emissions estimate from TNO has a higher fraction from fossil fuels than UKGHG (72% vs 67%). This results in larger simulated decreases in Δ14C per ppb CO for TNO emissions. The simulated differences between UKGHG and TNO are likely to be easily detectable by current measurement precision, suggesting that Δ14CO measurements could be an effective tool to understand regional CO sources and assess bottom-up emissions estimates.
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Journal articleDray L, Kuleszo J, Teoh R, et al., 2024,
Global air freight flow data for aviation policy modelling
, Journal of Air Transport Management, Vol: 121, ISSN: 0969-6997Models of air freight are often constrained by a lack of available data. This study brings together different sources of air freight supply and demand data to address this gap. To study air freight operations, we combine schedules, flight tracking data and country-level databases of passenger and freight movements to produce estimates of global flight segment-level capacity and load factors in freighter aircraft and passenger holds for 2019–2021. To study true origin-ultimate destination air freight demand, a freight mode choice model by commodity group is developed for 2019 to fill gaps in mode information in international and national trade datasets, and estimates are made for 2019 and 2021. Initial comparisons of supply and demand data demonstrate that air freight journeys differ significantly from passenger journeys, typically including more flight legs (roughly, around 2, compared to 1.2 for passengers) and greater leg distances (2.2–2.5 times average passenger distance), with significant asymmetry in commodity flows and operations to and from individual countries and regions. These differences persist in 2021, despite COVID-19 induced shifts towards carrying more air freight in freighter aircraft. This research forms a first step towards making available an integrated database of estimated global air freight flows by commodity.
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Journal articleSaceanu MC, Paluszny A, Ivars DM, et al., 2024,
Thermo-mechanical modelling of spalling around the deposition boreholes in an underground nuclear waste repository during its thermal phase
, International Journal of Rock Mechanics and Mining Sciences, Vol: 183, ISSN: 1365-1609This paper presents a three-dimensional numerical analysis of multiple fracture growth leading to the development of excavation disturbed zones and spalling around deposition boreholes in a geological disposal facility. The development of fracture patterns is simulated with the Imperial College Geomechanics Toolkit, a finite-element based simulator that can model the simultaneous nucleation, growth, and coalescence of multiple fractures in quasi-brittle rock. In these simulations, fractures develop due to the stress concentrations around the borehole wall, caused by the local in situ stresses, and due to the thermal stresses caused by the radioactive decay of the waste. Fracture patterns, and the extent of the spalled zone, are computed after the borehole drilling, heating, and cooling stages, at the Forsmark repository site in Sweden. The effect of temperature on the nucleation and growth of spalling fractures, as well as on the reactivation of pre-existing fractures, is assessed qualitatively, by comparing fracture patterns, and quantitatively, in terms of the maximum spalling depth, width, and increase in the total fractured surface area. Overall, the simulations presented herein indicate that thermal spalling will increase the depths (away from the borehole) and angular widths of the spalled zone, but is not likely to lead to major increases in fracture aperture, and concomitant increases in hydraulic transmissivity and permeability of the spalled zone, above that which has already been caused by mechanical spalling.
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