As part of the core facilities in the White City campus, the Department of Bioengineering have high specification liquid chromatography and mass spectrometry instruments. These instruments can be used to identify and quantify compounds and molecules in a wide range of matrices.
The instruments are available for use by all members of the department, the wider Imperial College community and beyond.
Assistance from a dedicated technician is also provided, along with expertise regarding sample preparation and experimental design.
Further information can be found on the facilities’ dedicated wiki pages.
Available instruments at White City
Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
The Q Exactive is a high specification mass spectrometer, equipped with: an API source with S-lens ion optics technology, injection flatapole with mass resolving capabilites, a quadrupole mass filter and collision cell for performing MS/MS experiments. It also has an Orbitrap mass analyser.
The Q Exactive has many applications and can be used in: metabonomics, proteomics, environmental and food safety, clinical research and forensic toxicology.
Some key features include:
- Resolving power up to 140,000
- Mass range for full scans: m/z 50 - 6000
- S-lens in source region increases sensitivity by injecting more ions into instrument
- Rapid scan-to-scan polarity switching allows for the identifcation of more compounds in single run
- Sample introduction via direct infusion into the API source or a HPLC system
Vanquish™ HPLC system