Partho Ghosh, Ph.D., is Professor of Chemistry & Biochemistry at the University of California, San Diego. His lab investigates how proteins of bacterial pathogens interact with mammalian targets through a combination of structural biology (i.e., X-ray crystallography, cryo-EM, NMR, SAXS, ), biochemistry, microbiology, cell biology, and reverse genetics. The Ghosh lab currently focuses its research efforts on Streptococcus pyogenes (Strep A), a major cause of global morbidity and mortality, as well as diversity-generating retroelements (DGRs), which are responsible for the highest level of protein sequence variation in the natural world and enable rapid adaptation of microbes to dynamic environments.