Sylvia Alonso

DOID seminar series (hybrid)

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Short Bio: Dr Sylvia Alonso

Dr Alonso obtained her PhD degree in Microbiology and Molecular Biology from Universite Claude Bernard Lyon I (France). She then continued her post-doctoral training at Pasteur Institut de Lille (France) where she developed bacterial vaccine delivery systems, followed by another 2 years at Cornell University (NY, USA) where she studied the molecular pathogenesis of tuberculosis. In 2004, she was awarded the Lee Kuan Yew post-doctoral Fellowship and joined the Department of Microbiology at the National University of Singapore (Singapore). She was recruited as an Assistant Professor in 2007 and promoted to Associate Professor with tenure in 2013. For the past 15 years, Dr Alonso’s research team has studied the host-pathogen interactions during viral infections, including Hand, Foot and Mouth Disease (HFMD) and Dengue. She has also pursued her long-time interest in vaccine development against viral diseases. 

 Abstract

Despite intensified research efforts, our understanding of dengue pathogenesis remains very patchy. Specifically, while the genetic diversity among dengue virus (DENV) strains has long been recognized, the resulting heterogeneity in virulence mechanisms has only started to be acknowledged. It hence appears that a one-size-fits-all treatment approach is not adequate to combat dengue in various parts of the world where different DENV strains circulate.

Affiliations:
1 Infectious Diseases Translational Research Programme (ID TRP); Department of Microbiology & Immunology; Yong Loo Lin School of Medicine; National University of Singapore, Singapore.
2 Immunology programme; Life Sciences Institute; National University of Singapore, Singapore.
3 National Centre for Infectious Diseases (NCID), Singapore.

 Current Positions:
-Tenured Associate Professor, National University of Singapore (NUS)
-Co-Director, Infectious Diseases Translational Research Programme (IDTRP); Yong Loo Lin School of Medicine, NUS.
-Deputy Director, Life Sciences Institute, NUS.
-Vaccine&Therapeutics Co-Op Lead, Programme for Research in Epidemic Preparedness and Response (PREPARE), Ministry of Health, Singapore.

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