Phylodynamics across viral evolutionary scales: from contemporary to ancient genomes
This seminar will focus on recent advancements in Bayesian phylodynamic methods for investigating the evolutionary and epidemiological dynamics of rapidly evolving viruses. These approaches leverage data integration, such as incorporating mobility and individual travel history in phylogeography, and have proven useful for uncovering dynamics over relatively short evolutionary time scales.
Inference over deep viral evolutionary time scales presents distinct modeling challenges. Dr Lemey will demonstrate how virus genomes from ancient samples can enhance our understanding of historical epidemics and how reconstructing hepatitis B virus evolution requires specific molecular clock models to reconcile rapid modern evolutionary rates with ancient co-divergence.
In-person event. If you wish to join online, please register here.
