BibTex format
@article{Björkstén:2008:10.1111/j.1399-3038.2007.00601.x,
author = {Björkstén, B and Clayton, T and Ellwood, P and Stewart, A and Strachan, D and ISAAC, Phase III Study Group},
doi = {10.1111/j.1399-3038.2007.00601.x},
journal = {Pediatr Allergy Immunol},
pages = {110--124},
title = {Worldwide time trends for symptoms of rhinitis and conjunctivitis: Phase III of the International Study of Asthma and Allergies in Childhood.},
url = {http://dx.doi.org/10.1111/j.1399-3038.2007.00601.x},
volume = {19},
year = {2008}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - In Phase III of the International Study of Asthma and Allergies in Childhood (ISAAC) time trends in the prevalence of rhinoconjunctivitis symptoms were analysed. Cross-sectional questionnaire surveys with identical protocols and questionnaires were completed a mean of 7 yr apart in two age groups comprising 498,083 children. In the 13- to 14-yr age group 106 centres in 56 countries participated, and in the 6- to 7-yr age group 66 centres in 37 countries participated. A slight worldwide increase in rhinoconjunctivitis prevalence was observed, but the variations were large among the centres and there was no consistent regional pattern. Prevalence increases in the older children exceeding 1% per year were recorded in 13 centres, including 3 of 9 centres in Africa, 2 of 15 in Asia-Pacific, 1 of 8 in India, 3 of 15 in Latin America, 3 of 9 in Eastern Europe and 1 of 34 in Western and Northern Europe. Decreasing rhinoconjunctivititis prevalence of similar magnitude was only seen in four centres. The changes were less pronounced in the 6- to 7-yr-old children and only in one centre did any change exceed 1% per year. The decrease in highest prevalence rates in ISAAC Phase I suggests that the prevalence has peaked in those regions. An increase was recorded in several centres, mostly in low and mid-income countries. The increases were more pronounced in the older age group, suggesting that environmental influences on the development of allergy may not be limited to early childhood.
AU - Björkstén,B
AU - Clayton,T
AU - Ellwood,P
AU - Stewart,A
AU - Strachan,D
AU - ISAAC,Phase III Study Group
DO - 10.1111/j.1399-3038.2007.00601.x
EP - 124
PY - 2008///
SP - 110
TI - Worldwide time trends for symptoms of rhinitis and conjunctivitis: Phase III of the International Study of Asthma and Allergies in Childhood.
T2 - Pediatr Allergy Immunol
UR - http://dx.doi.org/10.1111/j.1399-3038.2007.00601.x
UR - https://www.ncbi.nlm.nih.gov/pubmed/17651373
VL - 19
ER -