In this section
@article{Hassan:2024:10.1016/j.virusres.2024.199351,
author = {Hassan, S and Syun-Ichi, U and Shabeer, S and Kiran, TA and Wu, C-F and Moriyama, H and Coutts, RHA and Kotta, Loizou I and Jamal, A},
doi = {10.1016/j.virusres.2024.199351},
journal = {Virus Research},
title = {Molecular and biological characterization of a novel partitivirus from Talaromyces pinophilus},
url = {http://dx.doi.org/10.1016/j.virusres.2024.199351},
volume = {343},
year = {2024}
}
TY - JOUR
AB - Talaromyces spp. have a worldwide distribution, are ecologically diverse and have been isolated from numerous different substrates. Talaromyces spp. are considered biotechnologically important due to their ability to produce a range of enzymes and pigments. Talaromyces pinophilus, belonging to genus Talaromyces and family Trichocomaceae, is known for producing several important bioactive metabolites. Here we report the isolation and characterisation of a partitivirus from T. pinophilus which we have nominated Talaromyces pinophilus partitivirus-1 (TpPV-1). TpPV-1 possesses a genome consisting of three double stranded (ds) RNA segments i.e., dsRNAs1-3, 1824 bp, 1638 bp and 1451 bp respectively, which are encapsidated in icosahedral particles 35 nm in diameter. Both dsRNA1 and dsRNA2 contain a single open reading frame (ORF) encoding respectively a 572 amino acid (aa) protein of 65 kDa and a 504 aa protein of 50 kDa. The third segment (dsRNA3) is potentially a satellite RNA. Phylogenetic analysis revealed that the TpPV-1 belongs to the family Partitiviridae in the proposed genus Zetapartitivirus. TpPV-1 infection decreases the mycelial growth rate of the host fungus and alters pigmentation as indicated by time course experiments performed on a range of different solid media comparing virus-infected and virus-free isogenic lines. This is the first report of mycovirus infection in T. pinophilus and may provide insights into understanding the effect of the mycovirus on the production of enzymes and pigments by the host fungus.
AU - Hassan,S
AU - Syun-Ichi,U
AU - Shabeer,S
AU - Kiran,TA
AU - Wu,C-F
AU - Moriyama,H
AU - Coutts,RHA
AU - Kotta,Loizou I
AU - Jamal,A
DO - 10.1016/j.virusres.2024.199351
PY - 2024///
SN - 0168-1702
TI - Molecular and biological characterization of a novel partitivirus from Talaromyces pinophilus
T2 - Virus Research
UR - http://dx.doi.org/10.1016/j.virusres.2024.199351
UR - https://www.ncbi.nlm.nih.gov/pubmed/38453057
UR - http://hdl.handle.net/10044/1/111152
VL - 343
ER -
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