Citation

BibTex format

@article{Turner:2024:10.1016/S2468-2667(24)00163-4,
author = {Turner, P and Baseggio, Conrado A and Kallis, C and O'Rouke, E and Haider, S and Ullah, A and Custovic, D and Custovic, A and Quint, J},
doi = {10.1016/S2468-2667(24)00163-4},
journal = {The Lancet Public Health},
pages = {e664--e673},
title = {Time trends in the epidemiology of food allergy in England: an observational analysis of Clinical Practice Research Datalink data},
url = {http://dx.doi.org/10.1016/S2468-2667(24)00163-4},
volume = {9},
year = {2024}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundEstimates for the prevalence of food allergy vary widely, with a paucity of data for adults. The aim of this analysis was to report trends in the incidence and prevalence of food allergy in England, using a national primary care dataset.MethodsWe analysed data from Clinical Practice Research Datalink between 1998 and 2018, with linked data to relevant hospital encounters in England. The main outcomes were incidence and prevalence of food allergy, according to three definitions of food allergy: possible food allergy, probable food allergy, and probable food allergy with adrenaline autoinjectors prescription. We also evaluated the difference in proportion of patients prescribed adrenaline autoinjectors by English Index of Multiple Deprivation (IMD), age, and by previous food anaphylaxis, and explored differences in patient encounters (general practice vs emergency department setting).Findings7627607 individuals in the dataset were eligible for inclusion, of whom 150018 (median age 19 years [IQR 4–34]; 82614 [55·1%] female and 67404 [44·9%] male) had a possible food allergy. 121706 met diagnostic criteria for probable food allergy, of whom 38288 were prescribed adrenaline autoinjectors. Estimated incidence of probable food allergy doubled between 2008 and 2018, from 75·8 individuals per 100000 person-years (95% CI 73·7–77·9) in 2008 to 159·5 (156·6–162·3) individuals per 100000 person-years in 2018. Prevalence increased from 0·4% (23399 of 6432383) to 1·1% (82262 of 7627 607) over the same period and was highest in children under 5 years (11951 [4·0%] of 296406 in 2018) with lower prevalence in school-aged children (from 11353 [2·4%] of 473597in 2018 for children aged 5–9 years to 6896 [1·7%] of 404525 for those aged 15–19 years) and adults (42848 [0·7%] of 5992454in 2018). In those with previous food anaphyla
AU  - Turner,P
AU  - Baseggio,Conrado A
AU  - Kallis,C
AU  - O'Rouke,E
AU  - Haider,S
AU  - Ullah,A
AU  - Custovic,D
AU  - Custovic,A
AU  - Quint,J
DO  - 10.1016/S2468-2667(24)00163-4
EP  - 673
PY  - 2024///
SN  - 2468-2667
SP  - 664
TI  - Time trends in the epidemiology of food allergy in England: an observational analysis of Clinical Practice Research Datalink data
T2  - The Lancet Public Health
UR  - http://dx.doi.org/10.1016/S2468-2667(24)00163-4
UR  - https://www.sciencedirect.com/science/article/pii/S2468266724001634
VL  - 9
ER  -
Download