During infection, bacteria face the twin threats of antibiotics and the host immune system. Resistance to one sometimes confers resistance to the other.  

Researchers in this field include:  

• Dr Luke Allsopp: Bacterial secretion systems and biofilms factors
• Professor Darius Armstrong-James: Basis of fungal persistence and adaptation in the host, phenotypic microarray facility 
• Dr Thomas Clarke: Microbiota influence on host responses to bacterial infection and vaccination
• Dr Abigail Clements: The role of bacterial surface structures in pathogenesis
• Professor Marc Dionne: How do host defences promote acquisition of antimicrobial resistance?
• Dr Andy Edwards: Bacterial DNA repair systems
• Dr Ana Eulalio: Role of microRNAs and the impact of bacterial intracellular lifestyles on pathogenesis
• Dr Harry Low: Membrane remodelling processes to evade the immune system and develop resistance
• Dr Alex McCarthy: Pathogens exploitation of immunomodulatory receptors
• Dr Brian Robertson: Host pathogen-interactions underlying tuberculosis infection
• Dr Avinash Shenoy: Inflammasome evasion by enteric bacterial pathogens
• Dr Matthew Siggins: Bacterial virulence factors in invasion 
• Dr Teresa Thurston: Pathogen inhibition of innate immune signaling