GERF Case study - Human Challenge (readable format)

Key people and organisations involved (Imperial College): 

• The HIC-Vac network
• Professor Peter Openshaw
• Professor Chris Chiu
• National Heart and Lung Institute
• Department of Infectious Disease

Twitter:

• @ChrisChiuLab
• @p_openshaw
• @ImperialInfect
• @ImperialNHLI

Publications and news

• Killingley, et al. Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults. Nature Medicine (2022) 28: 1031–1041
• UK researchers to explore human challenge studies for COVID-19
• Results from the COVID-19 human challenge study

Funding

The HIC-Vac network was set-up with support from the GCRF Networks in Vaccines Research & Development, which is co-funded by the Medical Research Council (MRC) and the Biotechnology and Biological Sciences Research Council (BBSRC) (part of the EDCTP2 programme supported by the European Union).

The Network is now funded by the Wellcome Trust. 

Funding