In this section
@article{May:2023:10.1016/j.pt.2023.09.017,
author = {May, DA and Taha, F and Child, MA and Ewald, SE},
doi = {10.1016/j.pt.2023.09.017},
journal = {Trends in Parasitology},
pages = {1074--1086},
title = {How colonization bottlenecks, tissue niches, and transmission strategies shape protozoan infections},
url = {http://dx.doi.org/10.1016/j.pt.2023.09.017},
volume = {39},
year = {2023}
}
TY - JOUR
AB - Protozoan pathogens such as Plasmodium spp., Leishmania spp., Toxoplasma gondii, and Trypanosoma spp. are often associated with high-mortality, acute and chronic diseases of global health concern. For transmission and immune evasion, protozoans have evolved diverse strategies to interact with a range of host tissue environments. These interactions are linked to disease pathology, yet our understanding of the association between parasite colonization and host homeostatic disruption is limited. Recently developed techniques for cellular barcoding have the potential to uncover the biology regulating parasite transmission, dissemination, and the stability of infection. Understanding bottlenecks to infection and the in vivo tissue niches that facilitate chronic infection and spread has the potential to reveal new aspects of parasite biology.
AU - May,DA
AU - Taha,F
AU - Child,MA
AU - Ewald,SE
DO - 10.1016/j.pt.2023.09.017
EP - 1086
PY - 2023///
SN - 0169-4758
SP - 1074
TI - How colonization bottlenecks, tissue niches, and transmission strategies shape protozoan infections
T2 - Trends in Parasitology
UR - http://dx.doi.org/10.1016/j.pt.2023.09.017
UR - http://hdl.handle.net/10044/1/107762
VL - 39
ER -
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