Signalling in Prostate Cancer

What we do

We study the transduction of extracellular signals that determine cell fate and cell function in prostate cancer, particularly in metastatic and treatment-resistant disease. A major goal is to identify and characterise the cell-surface receptors and effectors of WNT family members and then use the information to develop new therapies. 

Why it is important

New treatments for prostate cancer have improved men´s lives but are also leading to the development of more aggressive, treatment-resistant cancer. Our research is aimed at finding new ways to prevent the growth and spread of treatment-resistant cancer.

How it can benefit patients

Our goal is to take the best of the inhibitors and function-blocking antibodies that we are presently studying in the lab to treat patients with prostate and other cancers.

Summary of current research

• Development of antibody nanoparticles for targeted treatment of cancer
• Characterisation of noncanonical Wnt signalling in cancer

Our researchers