How to Cost a Proposal

Golden Rules for Imperial’s main funders have been prepared by the Research Office and provide a simple summary on key funder requirements at proposal stage. 

While there is no expectation that investigators should know these, it is a useful resource to have access to.

Central Biomedical Services (CBS) provides and operates animal research facilities for the biomedical research community working to 'leading practice' guidelines, recognising that good laboratory animal welfare is an essential component of good laboratory animal technology and science. The multi-campus CBS facilities can accommodate a variety of species at various levels of discipline, including a full barrier unit, containment level 3 suites and quarantine facilities. Skilled and dedicated members of staff are able to provide professional help and advice.

Before commencing work within a CBS facility you must discuss your requirements with the Site Manager at the appropriate campus and be fully conversant with local rules and regulations.

The Central Biomedical Services webpages have access to CBS Costing Tool and CBS Notification Form.

The investigator should complete the relevant CBS costing tool and discuss this with the CBS team at the campus where the activity will take place. The approved CBS costing tool should then be sent to the Section Manager preparing the budgets who will extract the correct prices for the funder.

Imperial maintains an extensive range of research facilities and equipment spread across research disciplines and departments. A Directory of research facilities and equipment across Imperial College London was created to provide a searchable listing of research facilities and equipment to enable collaboration and improve efficiency and utilisation of existing equipment and facilities.

In some cases there are established charge rates for using the facilities (FILM and FACS have hourly rates which can be found on the charge out lists), which are updated annually.  Charged-out facilities can be included as a cost on all applications using the appropriate rate.

Other facilities may be available, but the costs may need to be established through a discussion with the facility manager or appropriate individual. Details of who to contact are included on the Facilities Directory. Costs for facilities which are not included on the charge out list cannot usually be included on Research Council applications, so please flag any required access to your Section Manager at an early stage so that these costs can be considered.

When preparing a project which involves a clinical trial there are many other considerations which must be included in the development of that application, to conform with the many aspects of clinical governance.

Clinical Electronic Case Records Forms

The Clinical Data Systems team within ICTU works collaboratively with Imperial College Investigators, Researchers, Study Managers and Statisticians, and Study Teams to provide an electronic data capture system for your Clinical Research Study, in line with regulatory standards.

There are two EDC tools that are available for electronic data capture depending on the clinical research being undertaken: OpenClinica V4.0 and REDCap (academic). InForm, the previous EDC tool, will no longer be used for new study releases after Nov 2020. The use of OpenClinica has been mandated for all Imperial College AHSC sponsored clinical trials of an IMP, however, other studies may use the OpenClinica system.

ICTU

The Imperial College Trials Unit is a UKCRC fully registered trials unit, which means that they have met certain standards of quality assessment in both academic and practical aspects of running trials. This status is recognized by funding agencies. Running a trial through ICTU will ensure that it is robust and is likely to help increase the chances of gaining successful funding.

ICTU operates in a collaborative way with investigators in order to ensure that both parties share their expertise most productively.

The ICTU webpages  contain very valuable information to support the development of clinical trials and NHLI supports an Operations manager (Dr Ana Boshoff) who will be able to provide further advice on projects and the adoption process for trials to be run through ICTU.

NHS Costs

As a university Imperial College is not able to directly cost work which will be undertaken in an NHS trust. Therefore all costs should be sought from the relevant NHS trust by the lead investigator as these relate to the specific study for which budgets are required. This also allows any questions or queries which arise to be addressed in the most timely manner.

Once obtained the approved NHS costs (as supplied by the relevant NHS trust’s R&D team) should be send to the Section Manager preparing the budgets.

SoECAT

All college-sponsored studies funded by a non-commercial organisation with NHS Trust costs will require a SoECAT (Schedule of Events Cost Attribution Template), if:

• The proposed study is intended for the NIHR CRN portfolio, the route through which support and Excess Treatment Costs are provided in England. This may include studies that will take place in a social care or public health setting.
• The research requires Health Research Authority (HRA) approval in England.
• The research will use NHS resources.

SoECATs are required for all funders which will use NHS resources, even if it does not include excess treatment costs (ETCs). In addition, some funders, namely research councils, require the completion of the SoECAT even if there are no NHS costs in the application

A full process map for the SoECAT preparation process is available.

A slight variation of this process relates to projects Royal Brompton & Harefield Hospitals where Imperial College will act as sponsor and RBHH is a single site. In such cases RBHH will require confirmation that the Sponsor has been involved in the completion process.

Responsibility for the completion of the SoECAT form rests with the investigator and sign off will be with the relevant AcoRD specialist in the NHS trust or in the LCRN if multi-site.

It should be noted that the SoECAT form is NOT itself a costing tool and the relevant NHS costs (see below) still need to be obtained from any involved NHS trusts. For projects involving ICHT this will require the ICHT non-commercial costing template to be completed but in all cases the investigators need to discuss their projects and requirements with the relevant NHS trust(s).

For small items of equipment it is possible to provide costs from online catalogues or the College’s ordering system (where often discounts are available) and include these as part of the application. For larger items (over £10,000) it is a requirement that quotes are obtained directly from the company for the specification of equipment which is required. Where several individual items of equipment are combined to make a single set-up, this will count as a single item. In addition, these items must be logged onto the Faculty's Equipment Database (if the application is successful), for insurance and equipment tracking.  Local laboratory managers can assist in this step.

Where specific needs are linked to the purchase of an item of equipment, such as dedicated space, require modification to existing laboratory space, single or 3 phase electrical supply etc, this should be discussed in advance of submission with Sue Francis.

In some cases, it is only feasible to purchase from a specific company, for example where the equipment will be used alongside existing items and must be compatible, and in those cases a single quote is acceptable at application stage.

In all cases, the costs of maintaining the new equipment should also be included in the purchase price. Normally this would be for 3 years but longer if allowed and the project runs more than 3 years.

The College’s Purchasing website contains more detailed information about the procurement process.

Professional fees apply to any activity which is to be conducted by a third party on behalf of the investigator in the delivery of the project. In all cases a quote for the work should be sought in advance of the submission to verify the costs and VAT will be relevant for service work regardless of whether this is applied by the company or not.

Imperial College has options for data storage which are managed through the Research Data Store.

While 2TB of storage is provided for each project free of charge, additional data storage is available at reasonable cost, with options for long term storage. The costs for this can be included in grant applications. Storage of data is also important in relation to the Research Data Management Plan.

When working with other universities or partners, where they are involved in the development of the science and will be co-applicants on the proposal, their involvement is managed as Research Partners. In such cases it is a requirement that they provide their own budgets for any work which will take place at their site, as these will be local costs which we cannot prepare. In addition, any under-budgeting as a result of the Research Partner not having provided their own costs will impact on our own budgets.

Once the activity at the Research Partner site has been established and finalised they will need to provide budget details. The Section Manager preparing the budgets can, is required, work with their equivalent at the other site to finalise these as needed for the application.

If part of the grant proposal includes someone who will register for a PhD the relevant fees should be included in the application costing.  This will vary according to the individual and may have a maximum threshold the funder is prepared to support.  Specific details will be included in the call or funder guidance.

Further details on PhD registration process are available with the NHLI website.