@article{Moore:2016:10.3201/eid2201.150139,
author = {Moore, LSP and Owens, DS and Jepson, A and Turton, JF and Ashworth, S and Donaldson, H and Holmes, AH},
doi = {10.3201/eid2201.150139},
journal = {Emerging Infectious Diseases},
pages = {9--17},
title = {Waterborne Elizabethkingia meningoseptica in adult critical care},
url = {http://dx.doi.org/10.3201/eid2201.150139},
volume = {22},
year = {2016}
}

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TY  - JOUR
AB  - Elizabethkingia meningoseptica is an infrequent colonizer of the respiratory tract; its pathogenicity is uncertain. In the context of a 22-month outbreak of E. meningoseptica acquisition affecting 30 patients in a London, UK, critical care unit (3% attack rate) we derived a measure of attributable morbidity and determined whether E. meningoseptica is an emerging nosocomial pathogen. We found monomicrobial E. meningoseptica acquisition (n = 13) to have an attributable morbidity rate of 54% (systemic inflammatory response syndrome >2, rising C-reactive protein, new radiographic changes), suggesting that E. meningoseptica is a pathogen. Epidemiologic and molecular evidence showed acquisition was water-source–associated in critical care but identified numerous other E. meningoseptica strains, indicating more widespread distribution than previously considered. Analysis of changes in gram-negative speciation rates across a wider London hospital network suggests this outbreak, and possibly other recently reported outbreaks, might reflect improved diagnostics and that E. meningoseptica thus is a pseudo-emerging pathogen.
AU  - Moore,LSP
AU  - Owens,DS
AU  - Jepson,A
AU  - Turton,JF
AU  - Ashworth,S
AU  - Donaldson,H
AU  - Holmes,AH
DO  - 10.3201/eid2201.150139
EP  - 17
PY  - 2016///
SN  - 1080-6059
SP  - 9
TI  - Waterborne Elizabethkingia meningoseptica in adult critical care
T2  - Emerging Infectious Diseases
UR  - http://dx.doi.org/10.3201/eid2201.150139
UR  - http://hdl.handle.net/10044/1/32266
VL  - 22
ER  - 

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