The publications below have arisen from the material supply or service provision from the Imperial College Healthcare Tissue Bank;
Publications
Contractor, K., Aboagye, E.O., Jacob, J., Challapalli, A., Coombes, R.C., & Stebbing, J. (2012) Monitoring early response to taxane therapy in advanced breast cancer with circulating tumor cells and [(18)F] 3´-deoxy-3´-fluorothymidine PET: a pilot study. Biomarkers in Medicine. 6(2):231-3.
PMID: 22448798. DOI: 10.2217/bmm.12.11.
Payne, R.E., Hava, N.L., Page, K., Blighe, K., Ward, B., Slade, M., Brown, J., Guttery, D.S., Zaidi, S.A., Stebbing, J., Jacob, J., Yagüe, E., Shaw, J.A., & Coombes, R.C. (2012) The presence of disseminated tumour cells in the bone marrow is inversely related to circulating free DNA in plasma in breast cancer dormancy. British Journal of Cancer. 106(2):375-82.
PMID: 22166803. DOI: 10.1038/bjc.2011.537.
Caballero, O.L., Shousha, S., Zhao, Q., Simpson, A.J., Coombes, R.C., & Neville, A.M. (2013) Expression of Cancer/Testis genes in ductal carcinoma in situ and benign lesions of the breast. Oncoscience. 1(1):14-20.
PMID: 25593980.
Huang, J., Kumar, S., Abbassi-Ghadi, N., Spanel, P., Smith, D., & Hanna, G.B. (2013) Selected ion flow tube mass spectrometry analysis of volatile metabolites in urine headspace for the profiling of gastro-esophageal cancer. Analytical Chemistry. 19;85(6):3409-16.
PMID: 23421902. DOI: 10.1021/ac4000656.
Kumar, S., Huang, J., Abbassi-Ghadi, N., Spanel, P., Smith, D., Hanna, G.B. (2013) Selected ion flow tube mass spectrometry analysis of exhaled breath for volatile organic compound profiling of esophago-gastric cancer. Analytical Chemistry. 85(12):6121-8.
PMID: 23659180. DOI: 10.1021/ac4010309.
Abbassi-Ghadi, N., Veselkov, K., Kumar, S., Huang, J., Jones, E., Strittmatter, N., Kudo, H., Goldin, R., Takáts, Z., Hanna, G.B. (2014) Discrimination of lymph node metastases using desorption electrospray ionisation-mass spectrometry imaging. Chemical Communications (Cambridge). 50(28):3661-4.
PMID: 24407514. DOI: 10.1039/c3cc48927b.
Blighe, K., Kenny, L., Patel, N., Guttery, D.S., Page, K., Gronau, J.H., Golshani, C., Stebbing, J., Coombes, R.C., & Shaw, J.A. (2014) Whole genome sequence analysis suggests intratumoral heterogeneity in dissemination of breast cancer to lymph nodes. PLoS One. 9(12):e115346.
PMID: 25546409 DOI: 10.1371/journal.pone.0115346.
Filipović, A., Lombardo, Y., Faronato, M., Abrahams, J., Aboagye, E., Nguyen, Q.D., d'Aqua, B.B., Ridley, A., Green, A., Rahka, E., Ellis, I., Recchi, C., Przulj, N., Sarajlić, A., Alattia, J.R., Fraering, P., Deonarain, M., & Coombes, R.C. (2014) Anti-nicastrin monoclonal antibodies elicit pleiotropic anti-tumour pharmacological effects in invasive breast cancer cells. Breast Cancer Research and Treatment. 148(2):455-62.
PMID: 25248409. DOI: 10.1007/s10549-014-3119-z.
Lombardo, Y., Faronato, M., Filipovic, A., Vircillo, V., Magnani, L., & Coombes, R.C. (2014) Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells. Breast Cancer Research. 16(3):R62.
PMID: 24919951 DOI: 10.1186/bcr3675.
Myatt, S.S., Kongsema, M., Man, C.W., Kelly, D.J., Gomes, A.R., Khongkow, P., Karunarathna, U., Zona, S., Langer, J.K., Dunsby, C.W., Coombes, R.C., French, P.M., Brosens, J.J., & Lam, E.W. (2014) SUMOylation inhibits FOXM1 activity and delays mitotic transition. Oncogene. 33(34):4316-29.
PMID: 24362530 DOI: 10.1038/onc.2013.546.
Rudraraju, B., Droog, M., Abdel-Fatah, T.M., Zwart, W., Giannoudis, A., Malki, M.I., Moore, D., Patel, H., Shaw, J., Ellis, I.O., Chan, S., Brooke, G.N., Nevedomskaya, E., Lo Nigro, C., Carroll, J., Coombes, R.C., Bevan, C., Ali, S., & Palmieri, C. (2014) Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer. Breast Cancer Research and Treatment. 147(2):295-309.
PMID: 25141981. DOI: 10.1007/s10549-014-3098-0.
Stebbing, J., Harding, V., Urch, C.E., Kaier, T., Schofield, G., Flook, M., Alifrangis, C., Young, A.M., Shaw, J.A., Coombes, R.C., & Krell, J. (2014) The prognostic role of circulating tumor cells in heavily pretreated individuals with a low life expectancy. Future Oncology. 10(16):2555-60.
PMID: 24877667. DOI: 10.2217/FON.14.107
Strittmatter, N., Rebec, M., Jones, E.A., Golf, O., Abdolrasouli, A., Balog, J., Behrends, V., Veselkov, K.A., & Takats, Z. (2014) Characterization and identification of clinically relevant microorganisms using rapid evaporative ionization mass spectrometry. Analytical Chemistry. 86(13):6555-62.
PMID: 24896667. DOI: 10.1021/ac501075f.
Veselkov, K.A., Mirnezami, R., Strittmatter, N., Goldin, R.D., Kinross, J., Speller, A.V., Abramov, T., Jones, E.A., Darzi, A., Holmes, E., Nicholson, J.K., & Takats, Z. (2014) Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. 111(3):1216-21.
PMID: 24398526 DOI: 10.1073/pnas.1310524111.
Mirnezami, R., Spagou, K., Vorkas, P.A., Lewis, M.R., Kinross, J., Want, E., Shion, H., Goldin, R.D., Darzi, A., Takats, Z., Holmes, E., Cloarec, O., & Nicholson, J.K. (2014) Chemical mapping of the colorectal cancer microenvironment via MALDI imaging mass spectrometry (MALDI-MSI) reveals novel cancer-associated field effects. Molecular Oncology. 8(1):39-49.
PMID: 24112879 DOI: 10.1016/j.molonc.2013.08.010.
Adams, C., Cazzanelli, G., Rasul, S., Hitchinson, B., Hu, Y., Coombes, R.C., Raguz, S., & Yagüe, E. (2015) Apoptosis inhibitor TRIAP1 is a novel effector of drug resistance. Oncology Reports. 34(1):415-22.
PMID: 25998939. DOI: 10.3892/or.2015.3988.
Challapalli, A., Trousil, S., Hazell, S., Kozlowski, K., Gudi, M., Aboagye, E.O., & Mangar, S. (2015) Exploiting altered patterns of choline kinase-alpha expression on human prostate tissue to prognosticate prostate cancer. Journal of Clinical Pathology. 68(9):703–709.
PMID: 26041862. DOI:10.1136/jclinpath-2015-202859.
Balog, J., Kumar, S., Alexander, J., Golf, O., Huang, J., Wiggins, T., Abbassi-Ghadi, N., Enyedi, A., Kacska, S., Kinross, J., Hanna, G.B., Nicholson, J.K., & Takats, Z. (2015) In vivo endoscopic tissue identification by rapid evaporative ionization mass spectrometry (REIMS). Angewandte Chemie (International Ed in English). 54(38):11059-62.
PMID: 26248566. DOI: 10.1002/anie.201502770.
Chiappini, C., Campagnolo, P., Almeida, C.S., Abbassi-Ghadi, N., Chow, L.W., Hanna, G.B., Stevens, M.M. (2015) Mapping Local Cytosolic Enzymatic Activity in Human Esophageal Mucosa with Porous Silicon Nanoneedles. Adv Mater. 27(35):5147-52.
PMID: 26197973. DOI: 10.1002/adma.201501304.
Golf, O., Muirhead, L.J., Speller, A., Balog, J., Abbassi-Ghadi, N., Kumar, S., Mróz, A., Veselkov, K., & Takáts, Z. (2015) XMS: cross-platform normalization method for multimodal mass spectrometric tissue profiling. Journal of the American Society for Mass Spectrometry. 26(1):44-54.
PMID: 25380777. DOI: 10.1007/s13361-014-0997-6.
Faronato, M., Nguyen, V.T., Patten, D.K., Lombardo, Y., Steel, J.H., Patel, N., Woodley, L., Shousha, S., Pruneri, G., Coombes, R.C., & Magnani, L. (2015) DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation. Oncotarget. 6(26):22467-79.
PMID: 26093085. DOI: 10.18632/oncotarget.4164.
Guenther, S., Muirhead, L.J., Speller, A.V., Golf, O., Strittmatter, N., Ramakrishnan, R., Goldin, R.D., Jones, E., Veselkov, K., Nicholson, J., Darzi, A., & Takats, Z. (2015) Spatially resolved metabolic phenotyping of breast cancer by desorption electrospray ionization mass spectrometry. Cancer Research. 75(9):1828-37.
PMID: 25691458. DOI:10.1158/0008-5472.CAN-14-2258.
Guttery, D.S., Page, K., Hills, A., Woodley, L., Marchese, S.D., Rghebi, B., Hastings, R.K., Luo, J., Pringle, J.H., Stebbing, J., Coombes, R.C., Ali, S., & Shaw, J.A. (2015) Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positive metastatic breast cancer. Clinical Chemistry. 61(7):97482.
PMID: 25979954. DOI:10.1373/clinchem.2015.238717.
Larner, F., Shousha, S., & Coombes, R.C. (2015) Zinc isotopes: a novel approach to biomarkers of breast cancer? Biomarkers in Medicine. 9(4):379-82.
PMID: 25808441. DOI: 10.2217/bmm.15.8.
Larner, F., Woodley, L.N., Shousha, S., Moyes, A., Humphreys-Williams, E., Strekopytov, S., Halliday, A.N., Rehkämper, M., & Coombes, R.C. (2015) Zinc isotopic compositions of breast cancer tissue. Metallomics. 7(1):112-7.
PMID: 25489714. DOI: 10.1039/c4mt00260a.
Lin, M.L., Patel, H., Remenyi, J., Banerji, C.R., Lai, C.F., Periyasamy, M., Lombardo, Y., Busonero, C., Ottaviani, S., Passey, A., Quinlan, P.R., Purdie, C.A., Jordan, L.B., Thompson, A.M., Finn, R.S., Rueda, O.M., Caldas, C., Gil, J., Coombes, R.C., Fuller-Pace, F.V., Teschendorff, A.E., Buluwela, L., & Ali, S. (2015) Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancer. Oncotarget. 6:21685-703.
PMID: 26280373. DOI: 10.18632/oncotarget.3942.
Magnani, L., Patten, D.K., Nguyen, V.T., Hong, S.P., Steel, J.H., Patel, N., Lombardo, Y., Faronato, M., Gomes, A.R., Woodley, L., Page, K., Guttery, D., Primrose, L., Fernandez Garcia, D., Shaw, J., Viola, P., Green, A., Nolan, C., Ellis, I.O., Rakha, E.A., Shousha, S., Lam, E.W., Győrffy, B., Lupien, M., & Coombes, R.C. (2015) The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer. Oncotarget. 6(26):21878-91.
PMID: 26215677. DOI: 10.18632/oncotarget.4243.
Nguyen, V.T., Barozzi, I., Faronato, M., Lombardo, Y., Steel, J.H., Patel, N., Darbre, P., Castellano, L., Győrffy, B., Woodley, L., Meira, A., Patten, D.K., Vircillo, V., Periyasamy, M., Ali, S., Frige, G., Minucci, S., Coombes, R.C., & Magnani, L. (2015) Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion. Nature Communications. 6:10044.
PMID:26610607. DOI: 10.1038/ncomms10044.
Periyasamy, M., Patel, H., Lai, C.F., Nguyen, V.T., Nevedomskaya, E., Harrod, A., Russell, R., Remenyi, J., Ochocka, A.M., Thomas, R.S., Fuller-Pace, F., Győrffy, B., Caldas, C., Navaratnam, N., Carroll, J.S., Zwart, W., Coombes, R.C., Magnani, L., Buluwela, L., & Ali, S. (2015) APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer. Cell Reports. 13(1):108-21.
PMID: 26411678. DOI:10.1016/j.celrep.2015.08.066.
Saleem, A., Searle, G.E., Kenny, L.M., Huiban, M., Kozlowski, K., Waldman, A.D., Woodley, L., Palmieri, C., Lowdell, C., Kaneko, T., Murphy, P.S., Lau, M.R., Aboagye, E.O., & Coombes, R.C. (2015) Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer. EJNMMI Research. 5:30.
PMID: 25977884. DOI: 10.1186/s13550-015-0103-5.
Sovova, K., Wiggins, T., Markar, S.R., & Hanna, G.B. (2015) Quantification of phenol in urine headspace using SIFT-MS and investigation of variability with respect to urinary concentration. Analytical Methods. 12(7)5134-5141.
DOI: 10.1039/C5AY01051A.
Abbassi-Ghadi, N., Jones, E.A., Gomez-Romero, M., Golf, O., Kumar, S., Huang, J., Kudo, H., Goldin, R.D., Hanna, G.B., & Takats, Z. (2016) A Comparison of DESI-MS and LC-MS for the Lipidomic Profiling of Human Cancer Tissue. Journal of the American Society for Mass Spectrometry. 27 (2): 255-64.
PMID: 26466600. DOI: 10.1007/s13361-015-1278-8.
Abbassi-Ghadi, N., Golf, O., Kumar, S., Antonowicz, S., McKenzie, J.S., Huang, J., Strittmatter, N., Kudo, H., Jones, E.A., Veselkov, K., Goldin, R., Takáts, Z., Hanna, G.B. (2016) Imaging of esophageal lymph node metastases by desorption electrospray ionization mass spectrometry Cancer Research. 76 (19): 5647-5656.
PMID: 27364550. DOI: 10.1158/0008-5472.CAN-16-0699.
Amrania, H., Drummond, L., Coombes, R.C., Shousha, S., Woodley-Barker, L., Weir, K., Hart, W., Carter, I., & Phillips, C.C. (2016) New IR imaging modalities for cancer detection and for intra-cell chemical mapping with a sub-diffraction mid-IR s-SNOM. Faraday Discussions. 187: 539-53.
PMID: 27077445. DOI: 10.1039/c5fd00150a.
Anderson, O., Carr, R., Harbinson, M., & Hanna, G.B. (2016) Development and validation of a lipase nasogastric tube position test. BMJ Open Gastroenterology. 2;3(1):e000064.
PMID: 26966548. DOI: 10.1136/bmjgast-2015-000064.
Krusche, B., Ottone, C., Clements, M.P., Johnstone, E.R., Goetsch, K., Lieven, H., Mota S.G., Singh, P., Khadayate, S., Ashraf, A., Davies, T., Pollard, S.M., De Paola, V., Roncaroli, F., Martinez-Torrecuadrada, J., Bertone, P., & Pattinello, S. (2016) EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells. eLife. 5: e14845.
PMID: 27350048. DOI: 10.7554/eLife.14845.
Tillner, J., McKenzie, J.S., Jones, E.A., Speller, A.V., Walsh, J.L., Veselkov, K.A., Bunch, J., Takats, Z., & Gilmore, I.S. (2016) Investigation of the Impact of Desorption ElectrosprayIonization Sprayer Geometry on Its Performance in Imaging of Biological Tissue. Analytical Chemistry. 88(9): 4808-16.
PMID: 27014929. DOI: 10.1021/acs.analchem.6b00345.
Zwart, W., Flach, K.D., Rudraraju, B., Abdel-Fatah, T.M., Gojis, O., Canisius, S., Moore, D., Nevedomskaya, E., Opdam, M., Droog, M., Hofland, I., Chan, S., Shaw, J., Ellis, I.O., Coombes, R.C., Carroll, J.S., Ali, S., & Palmieri, C. (2016) SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer. Clinical Cancer Research. 22:479-91.
PMID: 26369632. DOI: 10.1158/1078-0432.CCR-14-3277.
Ma S, Boughton O, Karunaratne A, Jin A, Cobb JP, Hansen U, Abel RL. (2016). Synchrotron imaging assessment of bone quality. Clinical Reviews in Bone & Mineral Metabolism 14:150.
Afshar, B., Turner, C.E., Lamagni, T.L., Smith, K.C., Al-Shabib, A., Underwood, A., Holden, M.T.G., Efstratious, A., Sriskandan, S. (2017) Enhanced nasopharyngeal infection and shedding associated with an epidemic lineage of emm3 group A Sreptocuccus. Virulence. 8(7):1390-1400
PMID: 28457962. DOI:10.1080/21505594.2017.1325070.
Afzali, B., Grönholm, J., Vandrovcova, J., O'Brien, C., Sun, H., Vanderleyden, I., Davis, F.P., Khoder, A., Zhang, Y., Hegazy, A.N., Villarino, A.V., Palmer, I.W., Kaufman, J., Watts, N.R., Kazemian, M., Kamenyeva, O., Keith, J., Sayed, A., Kasperaviciute, D., Mueller, M., Hughes, J.D., Fuss, I.L., Montgomery-Recht, K., McElwee, J., Restifo, N.P., Strober, W., Linterman, M.A., Wingfield, P.T., Uhlig, H.H., Rovchoudhuri, R., Aitman, T.J., Kelleher, P., Lenardo, M.J., O'Shea, J.J., Cooper, N., & Laurence, A.D.J. (2017) BACH2-immunodeficiency illustrates an association between super-enhancers and haplo-insufficiency. Nature Immunology. 18(7):813-823.
PMID: 28530713. DOI: 10.1038/ni.3753.
Cooke, S.L., Ennis, D., Evers, L., Dowson, S., Chan, M.Y., Paul, J., Hirschowitz, L., Glasspool, R.M., Singh, N., Bell, S., Day, E., Kochman, A., Wilkinson, N., Beer, P., Martin, S., Millan, D., Biankin, A.V., & McNeish, I.A. – on behalf of the Scottish Genomes Partnership (2017) The Driver Mutational Landscape of Ovarian Squamous Cell Carcinomas Arising in Mature Cystic Teratoma. Clinical Cancer Research. 23 (24): 7633 – 7640.
PMID: 28954785, DOI: 10.1158/1078-0432.CCR-17-1789.
Feildon, T. (2017) Osteoporosis drugs may make bones weaker. BBC News Online, 1 March 2017. https://www.bbc.co.uk/news/health-39122541.
Goranova, T., Ennis, D., Piskorz, A.M., Macintyre, G., Lewsley, L.A., Stobo, J., Wilson, C., Kay, D., Glasspool, R.M., Lockley, M., Brockbank, E., Montes, A., Walther, A., Sunday, S., Edmondson, R., Hall, G.D., Clamp, A., Gourley, C., Hall, M., Fotopoulou, C., Gabra, H., Freeman, S., Moore, L., Jimenez-Linan, M., Paul, J., Brenton, J.D., & McNeish, I.A. (2017) Safety and utility of image-guided research biopsies in relapsed high-grade serious ovarian carcinoma-experience of the BriTROC consortium. British Journal of Cancer. 116 (10): 1294 – 1301.
PMID: 28359078. DOI: 10.1038/bjc.2017.86.
Jin, A., Cobb, J., Hansen, U., Bhattacharya, R., Reinhard, C., Vo, N., Atwood, R., Li, J., Karunaratne, A., Wiles, C., & Abel, R. (2017) The effect of long-term bisphosphonate therapy on trabecular cone strength and microcrack density. Bone and Joint Research. 6 (10): 602 – 609.
PMID: 29066534, DOI: 10.1302/2046-3758.610.BJR-2016-0321.R1.
Khara, J.S., Obuobi, S., Wang, Y., Hamilton, M.S., Robertson, B.D., Newton, S.M., Yang, Y.Y., Langford, P.R., Ee, P.L.R. (2017) Disruption of drug-resistant biofilms using de novo designed short α-helical antimicrobial peptides with idealized facial amphiphilicity. Acta Biomaterialia. 57; 103 – 114.
PMID: 28457962. DOI: 10.106/j.actbio.2017.04.032.
Ma, S., Goh, E.L., Jin, A., Bhattacharya, R., Boughton, O.R., Patel, B., Karunaratne, A., Vo, N.T., Atwood, R., Cobb, J.P., Hansen, U., & Abel, R.L. (2017) Long-term effects of bisphosphonate therapy: perforations, microcracks and mechanical properties. Scientific Reports. 7:43399.
PMID: 28262693. DOI: 10.1038/srep43399.
Sim, M.J., Malaker, S.A., Khan, A., Stowell, J.M., Shabanowitz, J., Peterson, M.E., Rajagopalan, S., Hunt, D.F., Altmann, D.M., Long, E.O., & Boyton, R.J. (2017) Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-A Allotypes is Dictated by Peptides Bound to HLA-C. Frontiers in Immunology. 14 (8): 103.
PMID: 28352266. DOI: 10.3389/fimmu.2017.00193.
Stratigou, V., Doyle, A.F., Carlucci, F., Stephens, L., Foschi, V., Castelli, M., McKenna, N., Cook, H.T., Lightstone, L., Cairns, T.D., Pickering, M.C., & Botto, M. (2017) Altered expression of signalling lymphocyte activation molecule receptors in T-cells from lupus nephritis patients – a potential biomarker of disease activity. Rheumatology (Oxford). 56 (7); 1206 – 1216.
PMID: 28387859. DOI: 10.1093/rheumatology/kex078.
You, A.Y.F., Bergholt, M.S., St. Pierre, J.P., Kit-Anan, W., Pence, J., Chester, A.H., Yacoub, M.H., Bertazzo, S., & Stevens, M.M. (2017) Raman spectroscopy imaging reveals interplay between atherosclerosis and medial calcification in human aorta. Scientific Advances. 3 (12): e1701156.
PMID: 29226241. DOI: 10.1126/sciadv.1701156
Page K, Guttery DS, Fernandez-Garcia D, Hills A, Hastings RK, Luo J, Goddard K, Shahin V, Woodley-Barker L, Rosales BM, Coombes RC, Stebbing J, Shaw JA. (2017) Next Generation Sequencing of Circulating Cell-Free DNA for Evaluating Mutations and Gene Amplification in Metastatic Breast Cancer. Clin Chem. 2017 Feb;63(2):532-541. DOI: 10.1373/clinchem.2016.261834. Epub 2016 Dec 9.PMID: 27940449
Shaw JA, Guttery DS, Hills A, Fernandez-Garcia D, Page K, Rosales BM, Goddard KS, Hastings RK, Luo J, Ogle O, Woodley L, Ali S, Stebbing J, Coombes RC. (2019) Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts. Clin Cancer Res. 2017 Jan 1;23(1):88-96. DOI: 10.1158/1078-0432.CCR-16-0825. Epub 2016 Jun 22.PMID: 27334837
Boughton, O.R, Ma, S., Zhao, S., Arnold, M., Lewis, A., Hansen, U., Cobb, J.P., Giuliani, F., & Abel R.L. (2018) Measuring bone stiffness using spherical indentation. PLoS One. 13 (7): e0200475.
PMID: 30001364. DOI: 10.1371/journal.pone.0200475.
Curry, E., Zeller, C., Masrour, N., Patten, D.K., Gallon, J., Wilhelm-Benartzi, C.S., Ghaem-Maghami, S., Bowtell, D.D., & Brown, R. (2018) Genes Predisposed to DNA Hypermethylation during Acquired Resistance to Chemotherapy are Identified in Ovarian Tumours by Bivalent Chromatin Domains at Initial Diagnosis. Cancer Research. 78 (6): 1383 – 1391.
PMID: 29339543. DOI: 10.1158/0008-5472.CAN-17-1650.
Ghetti, M., Topouzi, H., Theocharidis, G., Papa, V., Williams, G., Bondioli, E., Cennacchi, G., Connelly, J.T., & Higgins, C.A. (2018) Subpopulations of dermal skin fibroblasts secrete distinct extracellular matrix: implications for using skin substitutes in the clinic. British Journal of Dermatology.
PMID: 29266210. DOI:10.1111/bjd.16255.
Markoska, A., Mendoza, L.C., Valaiyapathi, R., Thorn, C., & Dornhorst, A. (2018) Insulin sensitivity assessed using urine C-peptide creatinine ratio (UCPCR) in pregnancy: a cross sectional analysis of an English multi-ethnic cohort. BMJ Open. 8 (5): e020029.
PMID: 29724737. DOI: 10.1136/bmjopen-2017-020029.
Mason, S., Alexander, J.L., White, E., Bodai, Z., Manoli, E., Paizs, P., Alasdair, S., Adebesin, A., Hoare, J., Goldin, R., Darzi, A., Takats, Z., & Kinross, J.M. (2018) Sa1207 – Prospective Observational Cohort Study of Rapid Ionization Mass Spectrometry (REIMS) for Near-Real Time Diagnosis and Stratification of Colorectal Cancer. Gastroenterology. 154 (6) 1 S277- S278.
DOI:10.1016/S0016-5085(18)31288
Phelps, D.L., Balog, J., Gildea, L.F., Bodai, Z., Savage, A., El-Bahrawy, M.A., Speller, A.V., Rosini, F., Kudo, H., McKensie, J.S., Brown, R., Takats, Z., & Ghaem-Maghami, S. (2018) The surgical intelligent knife distinguishes normal, borderline and malignany gynaecological tissues using rapid evaporative ionisation mass spectrometry (REIMS). British Journal of Cancer. 118 (10): 1349 – 1358.
PMID: 29670294. DOI: 10.1038/s41416-018-0048-3.
Pickles, J.C., Hawkins, C., Pietsch, T., & Jacques, T.S. (2018) CNS embryonal tumours: WHO 2016 and beyond. Neuropathology and Applied Neurobiology. 44 (2): 151 – 162.
PMID: 28949028. DOI: 10.1111/nan.12443.
Pinato, D.J., Mauri, F.A., Spina, P., Cain, O., Siddique, A., Goldin, R.D., Victor, S., Pizio, C., Akarca, A., Boldorini, R., Mazzucchelli, L., Black, J.M., Shetty, S., Marafioti, T., & Sharma, R. (2018) Quantitative compatison of PD-L1 immuno-histochemical assays in hepatocellular carcinoma: The Blueprint-HCC study. Journal of Clinical Oncology. 36 (5) 91.
DOI: 10.1016/S0168-8278(18)31595-2
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Current Newsletter
Imperial College HTA Matters & Tissue Biobank Newsletter December 2022
