List of Approved NIHR HIC Cardiovascular Theme Projects

Information on projects approved by the NIHR Health Informatics Collaborative (HIC) Cardiovascular Theme Scientific Steering Group can be found below.

Project List:

Utilizing Machine-Learning for Prediction of Thromboembolism within 30-days of Hospitalization in COVID-19 Patients

Lead Site: Imperial

Database Accessed: COVID-19 Research Database

The prognostic significance of blood pressure variability in patients admitted to hospital with COVID-19

Lead Site: Imperial

Database Accessed: COVID-19 Research Database

The prognostic significance of blood pressure variability in patients admitted to hospital with acute coronary syndrome

Lead Site: Imperial

Database Accessed: COVID-19 Research Database

Cardiovascular Outcomes for Patients undergoing High-Risk Noncardiac Surgery

Lead Site: Kings College London

Database Accessed: COVID-19 Research Database

Investigation, management and clinical outcomes of suspected myocardial injury or infarction during the COVID-19 pandemic

Lead Site: Oxford

Database Accessed: COVID-19 Research Database

Investigating the effect of the COVID-19 pandemic on the incidence of arrhythmias

Lead Site: Imperial & Leicester

Database Accessed: COVID-19 Research Database

Validation of a Novel Scoring Algorithm for Hyperinflammatory State in COVID-19

Lead Site: Southampton

Database Accessed: COVID-19 Research Database

Mortality and complications in patients with and without SARS-CoV-2 infection undergoing CV and non-CV r intervention in 5 UK hospitals

Lead Site: Bristol & Oxford

Database Accessed: COVID-19 Research Database

What is the effect of cardiovascular medications on the outcome of patients with COVID-19?

Lead Site: Imperial

Database Accessed: COVID-19 Research Database

What is the impact of age, sex, ethnicity and obesity on outcomes following COVID-19 infection?

Lead Site: Kings College London & GSTT

Database Accessed: COVID-19 Research Database

Investigating the association between comorbidity clusters and adverse hospital outcomes among COVID-19 patients

Lead Site: UCL

Database Accessed: COVID-19 Research Database

Trial emulation to compare anti-coagulation strategies for COVID-19 hospital admissions

Lead Site: Imperial & Bristol

Database Accessed: COVID-19 Research Database

Guiding antithrombotic therapies in patients with high bleeding risk

Lead Site: Bristol

Database Accessed: ACS Research Database

The prognostic value of troponin in patients admitted to hospital with pneumonia: the NIHR TROP-PNEUMONIA study

Lead Site: Imperial

Database Accessed: ACS Research Database

The effect of social deprivation on clinical outcomes following acute coronary syndromes

Lead Site: Kings College London

Database Accessed: ACS Research Database

Association between glycaemic control, cardiovascular outcomes and mortality in the context of acute coronary syndrome

Lead Site: Imperial

Database Accessed: ACS Research Database

Precision Medicine for Heart Failure with Preserved Ejection Fraction

Lead Site: Manchester

Database Accessed: ACS Research Database

Readmission after Acute Coronary Syndrome: development and internal validation of a clinical prediction model

Lead Site: Manchester

Database Accessed: ACS Research Database

Designing a decision support tool for patients with acute coronary syndrome using electronic health records

Lead Site: Leicester

Database Accessed: ACS Research Database

The Benefit of Early TransThoracic EchocardiogRaphy in Acute Heart Failure: The Better Study

Lead Site: Leicester & Birmingham

Database Accessed: ACS Research Database

Peri-Procedural Troponin Release After CABG and its PCI and Prognostic Implication

Lead Site: Imperial & Bristol

Database Accessed: ACS Research Database

A New Prediction Model for Short and Long Term Survival After Acute Coronary Syndromes

Lead Site: Imperial & Bristol

Database Accessed: ACS Research Database

Equity of Access to Care for Acute Myocardial Infarction in People with Chronic Kidney Disease

Lead Site: Bristol

Database Accessed: ACS Research Database

Out of Hospital Cardiac Arrest

Lead Site: Bristol

Database Accessed: ACS Research Database

The Prognostic Significance of Cardiac Troponin Levels in Patients Presenting with Pulmonary Embolism (NIHR TROP-PE Study)

Lead Site: Imperial

Database Accessed: ACS Research Database

Association between pre-operative troponin levels and clinical outcome following CABG surgery (TROP-CABG Study)

Lead Site: Imperial & Bristol

Database Accessed: ACS Research Database

Invasive versus non-invasive management in patients with type 2 myocardial infarction (NIHR T2MI Study)

Lead Site: Imperial

Database Accessed: ACS Research Database

Identifying the risk factors associated with ventricular arrhythmia in patients with ACS – NIHR VA-ACS Study

Lead Site: Imperial

Database Accessed: ACS Research Database

Association between dynamic troponin elevation and mortality in acute stroke syndromes – NIHR TROP-STROKE Study

Lead Site: Imperial

Database Accessed: ACS Research Database

Prognostic Significance of Raised Cardiac Troponin in Patients Presenting with Malignancy

Lead Site: Imperial

Database Accessed: ACS Research Database

Association between blood pressure and long-term outcomes in patients with heart failure and preserved ejection fraction with and without AF

Lead Site: Kings College London

Database Accessed: ACS Research Database

Prognostic Value of High-Sensitivity Troponin in Patients with Acute Heart Failure: A Cohort Study using the NIHR HIC

Lead Site: Kings College London

Database Accessed: ACS Research Database

The relationship between acute and chronic myocardial injury and mortality

Lead Site: Imperial

Database Accessed: ACS Research Database

Clinical Importance of Troponin in Patients Presenting with Atrioventricular Block (BRADY-TROP STUDY)

Lead Site: Imperial

Database Accessed: ACS Research Database

Re-examination of diagnostic and prognostic optimal cut-offs values of high-sensitivity cardiac troponin T and I using machine learning analysis

Lead Site: Imperial

Database Accessed: ACS Research Database

Elevated troponin and diagnosis and prognosis among patients with chronic kidney disease: a cohort study using the NIHR HIC

Lead Site: UCL

Database Accessed: ACS Research Database

Blood sodium and potassium and prognosis of acute cardiovascular syndromes: a cohort study using the NIHR HIC

Lead Site: UCL

Database Accessed: ACS Research Database

THE NIHR SEPSIS TROPONIN RISK STUDY

Lead Site: Imperial

Database Accessed: ACS Research Database

Cholesterol level, age and mortality - THE NIHR CHOLESTEROL RISK STUDY

Lead Site: Imperial

Database Accessed: ACS Research Database

hsCRP Predicts Mortality Beyond Troponin in 102,337 Patients With Suspected ACS in the UK (NIHR CRP-RISK Study)

Lead Site: Imperial

Database Accessed: ACS Research Database

Clinical Importance of Troponin Level in Patients Presenting With Atrial Fibrillation (AF-TROP Study)

Lead Site: Imperial

Database Accessed: ACS Research Database

Invasive versus non-invasive management of elderly patients with non-ST elevation myocardial infarction (SENIOR-NSTEMI Study)

Lead Site: Imperial

Database Accessed: ACS Research Database

Troponin level, age and mortality risk in an unselected population of over 250000 patients – TROP-RISK study

Lead Site: Imperial

Database Accessed: ACS Research Database

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