THE STUDY

COLLABORATE is an efficient, UK-wide, real-world-data-enabled, adaptive, 2-randomisation, controlled trial to determine clinical efficacy, effect size, and safety of widely used enteral feeds in reducing necrotising enterocolitis, mortality, and cognitive impairment in extremely preterm babies.

COLLABORATE is supported by NEC UK, Bliss, Adult Preemie Advocacy Network, The George Institute for Global Health, Neonatal Dieticians Interest Group, British Association for Neonatal Neurodevelopmental Follow-Up, and British Association of Paediatric Surgeons.

ENGAGEMENT MATERIALS

NEW!
We invite you to join one of our upcoming COLLABORATE webinars where the investigators will explain the study and provide opportunity for discussion and questions. Sessions are open to everyone and we encourage all neonatal team members (doctors, nurses, dieticians, and other health professionals) to join. The online sessions will be held on Microsoft Teams. Dates and links are provided below.

Joining Instructions

Once joining, please wait in the lobby to be admitted, mute your microphone, and label your video screen with your name.

·       Session 1: 19th February, 12.00-13.00Click to join

·       Session 2: 21st February, 12.00-13.00Click to join

·       Session 3: 26th February, 12.00-13.00Click to join

·       Session 4: 28th February, 12.00-13.00Click to join

·       Session 5: 7th March,12.00-13.00Click to join

·       Session 6: 19th March, 13.00-14.00Click to join

·       Session 7: 26th March, 13.00-14.00Click to join

Watch this short explainer below:

 

Explainer Video

This video was co-produced and created by Desmond Danso Sakyi, the Research Communications Lead for the Neonatal Medicine Research Group, Imperial College London.

STUDY GOALS

  • Randomisation 1 will determine if pasteurised human donor milk or preterm formula affect NEC and other outcomes if a supplement for own mother’s milk is required.
  • Randomisation 2 will determine if routine macronutrient fortification of human milk is beneficial.

INVESTIGATORS

COLLABORATE is led by Victoria CORNELIUS (Professor of Medical Statistics and Trial Methodology, Imperial College London), Neena MODI (Professor of Neonatal Medicine, Imperial College London), James BOARDMAN (Professor of Neonatal Medicine, University of Edinburgh), Peter BRADLEY (Director of Services, Bliss), Lauren INGLEDOW (Adult Preemie Advocacy Network), Annemarie LODDER (Parent, Patient and Public Involvement and Engagement Lead, Pregnancy and Prematurity theme, NIHR Biomedical Research Centre, Imperial College London), Ramon LUENGO-FERNANDEZ (Associate Professor of Health Economics, University of Oxford), Andrew MORRIS (Director, Health Data Research UK), John NORRIE (Professor of Medical Statistics, Queen’s University Belfast), Shalini OJHA (Professor of Neonatal Medicine, University of Nottingham), David QUINE (Consultant Neonatologist, Edinburgh Royal Infirmary), Sabita UTHAYA (Consultant Neonatologist, Professor of Practice, Imperial College London), James WASON (Professor of Biostatistics, University of Newcastle), and Hilary WONG (Consultant Neonatologist, Affiliated Assistant Professor, University of Cambridge)

TRIALS UNIT

COLLABORATE is a National Neonatal Research Database enabled study and will be delivered by the Imperial Clinical Trials Unit

FOLLOW COLLABORATE

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CONTACTS

Please email us at COLLABORATE@imperial.ac.uk if you have any questions or would like us to visit your neonatal unit or network to discuss COLLABORATE.

WATCH THIS SPACE; MORE DETAILS TO COME!

 

General enquiries


Neonatal Medicine Research Group and Neonatal Data Analysis Unit Manager
(All research related queries)
Room G 4.3
Chelsea and Westminster Hospital

ndau@imperial.ac.uk
+44 (0)20 3315 5841

Research Communications Lead
(Communications related queries only)
dsakyi@imperial.ac.uk 

Online Portals
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