Molecular and Translational Haematology Course Guide
Key Information
Start Date
Monday 26th September 2022
Campus
Course Spaces
10 spaces for non-Imperial students
Introduction
The BSc in Medical Sciences with Molecular and Translational Haematology is designed to provide a thorough understanding of haematological disorders and their modern-day treatment. The programme has a strong emphasis on haematological research and aims to create clinicians and academics with the ability to interpret and inform best practice. Topics covered include:
- The scientific basis of many aspects of haematology, including thalassaemia, haemoglobinopathies, red cells, enzymopathies, bone marrow failure syndromes
- The science of blood transfusion, thrombosis and normal and abnormal haemostasis,
- Leukaemia, lymphoma and multiple myeloma
- How recent research and scientific advances are now influencing the diagnostic approach, the design of drugs and the management of patients with haematological disorders
This programme will take students through a research journey, culminating in a 15-week research project. It will enable students to grow into competent clinicians and clinical researchers that could lead to postgraduate research studies.
Course Structure and Term Dates
The programme is comprised of three modules. Module 1 is a 12-week teaching block where the students gain specialism-specific knowledge and skills, alongside their core research training. Module 2 involves self-directed learning, including a group literature review and clinical case study. In Module 3, students undertake a 15-week research project.
The Molecular and Translational Haematology term dates can be found in the downloadable
Programme Structure
Module 1
Module 1 - The Taught Module
Module 1 is a 12-week teaching block. Students will receive interactive, engaging sessions from leading experts in the field of haematological research. Topics covered in this module include:
- The role of the haematopoietic system
- Leukemia, multiple myeloma, lymphoma and myelodysplasia
- Red cells, thalassaemias, haemoglobinopathies
- Automunity and cellular therapies
- Haemostasis and clotting
Module 1 Assessment
Module 1 is assessed via three pieces of in-course assessment which account for 30% of the overall BSc mark:
- Written Task (15% of Module 1)
Students will write a 1,000-word 'Critic at Large' article which will address topical or controversial area of scientific research.
- Oral Task (15% of Module 1)
Students will give a 10-minute poster presentation critically evaluating an area of cancer research followed by 5-minutes of questions from assessors.
- Data Management and Interpretation (70% of Module 1)
Students will undertake laboratory research and produce a results compendium analysing and interpreting the data, along with a scientific abstract and a lay summary.
How is this Module Taught?
Module 1 provides a blend of face to face teaching on campus, lab work and online teaching. We aim to make our teaching as interactive as possible to promote student engagement and cohort building.
The module includes 3 consolidation weeks without teaching, where students can work on assessments, associated self-directed learning, on-line modules and group work. The consolidation weeks will also provide an opportunity to meet with the Course Lead to discuss progress, issues and receive feedback on course work and progression.
Module 2
Module 2 - Self-Directed Learning
Module 2 is a 5-week block which provides students with a collaborative experience of working with their peers to provide a critical synthesis of a scientific problem. Students will also work independently on a clinical case study involving a real patient, where they will investigate the science underpinning the patient's diagnosis and treatment.
Module 2 Assessment
Module 2 is assessed via two pieces of in-course assessment which account for 25% of the overall BSc mark:
Group Literature Review (25% of Module 2)
Students will work in groups of 4-5 to develop their team working, communication, critical appraisal and clinical translation skills through a literature review assignment that focusses on translation of basic understanding of cancer into patient-orientated research.
This assignment is submitted in 3 stages and is designed to mirror the process of submitting research to a scientific journal:
- Each group will produce a 3,500-word critical summary of a cutting-edge area of cancer research
- They will then produce a 1,000-word review of another group's critical summary
- Finally, groups will produce a revised critical summary addressing the peer referee group’s comments
Science in Context (10% of Module 2)
Students will work independently on a 1,500-word report summarising a real-life clinical case and providing an in-depth critique of the current and emerging evidence for either the underlying cause of the disorder or current treatment options.
How is this Module Taught?
Module 2 is self-directed learning so there are guidance sessions but no taught sessions. For both pieces of Module 2 assessment, all students will be supported by an academic supervisor who is an expert in the field of study.
Module 3
Module 3 - Research Project
In Module 3 students will conduct a 14-week supervised research project resulting in a project write-up in the style of an academic research paper. Students will have opportunity for critical reflection on design of research, validation of approach, and robustness of data interpretation.
Students will choose from a range of current and topical research projects. Examples of past projects include:
Clinical Projects
- Bleeding and thrombotic complications from Temporary circulatory support for cardiogenic shock
- Changes in depth of response after autologous stem cell transplantation in multiple myeloma and their importance for clinical outcome
- The non-malignant morbidity of HTLV-1
Laboratory Projects
- Tissue factor pathway inhibitor (TFPI) defining the mode of action of an essential anticoagulant
- ADAMTS13 conformation: determinant of function and targeting as an autoantigen in TTP
- Functional analysis of the upstream promoter region of the EVI1 oncogene inEVI1+ myeloid leukaemia cells
Module 3 Assessment
Module 3 is assessed via two pieces of in-course assessment which account for 45% of the overall BSc mark:
Project Report (78% of Module 3)
Students will produce a 5,000-word project report.
Oral Presentation of Project (22% of Module 3)
Students will give a 10-minute oral presentation reflecting on their individual research journey and future research directions, followed by 5-minutes of questions.
How is this Module Taught?
All students will have a dedicated project supervisor who will be a senior academic at Imperial. The supervisor will guide support the student throughout their research journey.
Additional support will be provided by the Module Lead, who will run regular project support sessions. Students will give a project progress presentation with their BSc Molecular and Translational Haematology cohort at regular intervals.
Meet the Team
Meet the Team
Professor Jim Crawley
![Professor Jim Crawley](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/faculty-of-medicine/jim-crawley_1639388295031_x4.jpg)
Professor Jim Crawley
Course Director
Celeste Miles
![Celeste Miles](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/faculty-of-medicine/celeste-miles_1639388469208_x4.jpg)
Celeste Miles
Course Administrator
Dr Josefin Ahnstrom
![Josefin Ahnstrom](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/faculty-of-medicine/josefin-ahnstrom_1639391169731_x4.jpg)
Dr Josefin Ahnstrom
Module 1 Lead
Professor Jane Apperley
![Jane Apperley](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/faculty-of-medicine/jane-apperley_1639391328497_x4.jpg)
Professor Jane Apperley
Module 2 Lead
Dr Niklas Feldhahn
![Niklas Feldhahn](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/faculty-of-medicine/niklas-feldhahn_1639391432535_x4.jpg)
Dr Niklas Feldhahn
Module 3 Lead
Student Support
We know that joining a new university can be daunting so we will do all we can to make you feel welcome at Imperial and help you to integrate within your cohort.
Our Imperial School of Medicine Student Union (ICSMSU) run fantastic welcome events for new intercalating students and the Molecular and Translational Haematology Team will run activities to help support students in getting to know one another. We also run a BSc Buddy Scheme which you can join to be matched with internal Imperial students on your BSc or on one of our other iBScs.
Each student will also be assigned an Academic Tutor who can support on both academic and pastoral matters throughout the BSc. We have a wide range of student support provisions, systems and services designed to assist you throughout your studies. Please find further information in the Imperial Student Support Zone.