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  • Book chapter
    Ghani R, Mullish BH, 2020,

    Decision: Considerations for Use of Fecal Microbiota Transplantation in Special Patient Populations

    , The 6 Ds of Fecal Microbiota Transplantation: A Primer from Decision to Discharge and Beyond, Editors: Allegretti, Kassam, Publisher: Slack Incorporated, ISBN: 9781630917500
  • Book chapter
    Mullish BH, 2020,

    The Role of Fecal Microbiota Transplantation in the Treatment of Obesity, Metabolic Syndrome, and Nonalcoholic Fatty Liver Disease

    , The 6 Ds of Fecal Microbiota Transplantation: A Primer from Decision to Discharge and Beyond, Editors: Allegretti, Kassam, Publisher: Slack Incorporated, ISBN: 9781630917500
  • Journal article
    Alexander JL, Mullish BH, 2020,

    A Guide to the Gut Microbiome and its Relevance to Critical Care

    , British Journal of Nursing, Vol: 29, Pages: 1106-1112, ISSN: 0966-0461

    <jats:p> Although it is well-established that particular bacteria may cause gastroenteritis and other infections when present in the gut, it is only recently that scientists have made significant inroads into understanding the huge number of other bacteria and additional microbes that live within the gastrointestinal tract, referred to as the gut microbiome. In particular, it is now recognised that bacteria within the gut microbiome have a wide variety of roles in maintaining different aspects of human health, and that disturbances of these bacteria may potentially cause or contribute to a number of different medical conditions, including particular infections, certain cancers, and chronic conditions, including inflammatory bowel disease. Moreover, there is increasing awareness that these bacteria help determine how the body responds to medication, including antibiotics and chemotherapy. There has been growing interest in different approaches to alter the gut microbiome as a novel approach to medical therapy. This article provides an overview of the importance of the gut microbiome, with a particular focus on critical care. </jats:p>
  • Conference paper
    Allegretti JR, Kelly C, Grinspan AM, Mullish BH, Hurtado J, Nemes S, Sagi S, Bohm M, Kassam Z, Fischer Met al., 2020,

    S0650 Fecal Microbiota Transplantation Decolonizes C. difficile in Patients With Inflammatory Bowel Disease and Concomitant C. difficile Infection

    , Publisher: Ovid Technologies (Wolters Kluwer Health), Pages: S326-S326, ISSN: 0002-9270
  • Journal article
    Ianiro G, Segal JP, Mullish BH, Quraishi MN, Porcari S, Fabiani G, Gasbarrini A, Cammarota Get al., 2020,

    Fecal microbiota transplantation in gastrointestinal and extraintestinal disorders

    , Future Microbiology, ISSN: 1746-0913
  • Journal article
    Segal JP, Mullish BH, Quraishi MN, Iqbal T, Marchesi JR, Sokol Het al., 2020,

    Mechanisms underpinning the efficacy of faecal microbiota transplantation in treating gastrointestinal disease

    , Therapeutic Advances in Gastroenterology, Vol: 13, Pages: 1-14, ISSN: 1756-2848

    Faecal Microbiota transplantation is currently a recommended therapy for recurrent/refractory Clostridioides difficile infection. The success of FMT for CDI has led to interest in its therapeutic potential in many other disorders. The mechanisms that underpin the efficacy of FMT are not fully understood. Importantly, FMT remains a crucial treatment in managing CDI and hence understanding the mechanisms that underpin its success will be critical to improve its clinical efficacy, safety and usability. Furthermore, a deeper understanding may allow us to expose FMT’s full potential as a therapeutic tool for other disease states. This review will explore the current understanding of the mechanisms underlying the efficacy of FMT across a variety of diseases.
  • Journal article
    Ianiro G, Mullish BH, Kelly CR, Kassam Z, Kuijper EJ, Ng SC, Iqbal TH, Allegretti JR, Bibbò S, Sokol H, Zhang F, Fischer M, Costello SP, Keller JJ, Masucci L, van Prehn J, Quaranta G, Quraishi MN, Segal J, Kao D, Satokari R, Sanguinetti M, Tilg H, Gasbarrini A, Cammarota Get al., 2020,

    Reorganisation of faecal microbiota transplant services during the COVID-19 pandemic

    , Gut, Vol: 69, Pages: 1555-1563, ISSN: 0017-5749

    <jats:p>The COVID-19 pandemic has led to an exponential increase in SARS-CoV-2 infections and associated deaths, and represents a significant challenge to healthcare professionals and facilities. Individual countries have taken several prevention and containment actions to control the spread of infection, including measures to guarantee safety of both healthcare professionals and patients who are at increased risk of infection from COVID-19. Faecal microbiota transplantation (FMT) has a well-established role in the treatment of<jats:italic>Clostridioides difficile</jats:italic>infection. In the time of the pandemic, FMT centres and stool banks are required to adopt a workflow that continues to ensure reliable patient access to FMT while maintaining safety and quality of procedures. In this position paper, based on the best available evidence, worldwide FMT experts provide guidance on issues relating to the impact of COVID-19 on FMT, including patient selection, donor recruitment and selection, stool manufacturing, FMT procedures, patient follow-up and research activities.</jats:p>
  • Journal article
    Segal JP, Mullish BH, Quraishi MN, Iqbal THet al., 2020,

    Letter: faecal microbiota transplantation for IBS

    , Alimentary Pharmacology &amp; Therapeutics, Vol: 52, Pages: 556-557, ISSN: 0269-2813

    <jats:p><jats:bold>LINKED CONTENT</jats:bold></jats:p><jats:p>This article is linked to Lahtinen et al papers. To view these articles, visit<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="https://doi.org/10.1111/apt.15810">https://doi.org/10.1111/apt.15810</jats:ext-link> and <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="https://doi.org/10.1111/apt.15875">https://doi.org/10.1111/apt.15875</jats:ext-link>.</jats:p>
  • Journal article
    McIlroy JR, Mullish BH, Goldenberg SD, Ianiro G, Marchesi JRet al., 2020,

    Intestinal microbiome transfer, a novel therapeutic strategy for COVID-19 induced hyperinflammation?

    , Clinical Immunology, ISSN: 1521-6616
  • Journal article
    Vieira-Silva S, Falony G, Belda E, Nielsen T, Aron-Wisnewsky J, Chakaroun R, Forslund SK, Assmann K, Valles-Colomer M, Nguyen TTD, Proost S, Prifti E, Tremaroli V, Pons N, Le Chatelier E, Andreelli F, Bastard J-P, Coelho LP, Galleron N, Hansen TH, Hulot J-S, Lewinter C, Pedersen HK, Quinquis B, Rouault C, Roume H, Salem J-E, Sondertoft NB, Touch S, Dumas M-E, Ehrlich SD, Galan P, Gotze JP, Hansen T, Holst JJ, Kober L, Letunic I, Nielsen J, Oppert J-M, Stumvoll M, Vestergaard H, Zucker J-D, Bork P, Pedersen O, Backhed F, Clement K, Raes Jet al., 2020,

    Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

    , NATURE, Vol: 581, Pages: 310-+, ISSN: 0028-0836

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