@article{Russell:2013:10.1016/j.mib.2013.07.002,
author = {Russell, WR and Hoyles, L and Flint, HJ and Dumas, ME},
doi = {10.1016/j.mib.2013.07.002},
journal = {Current Opinion in Microbiology},
title = {Colonic bacterial metabolites and human health},
url = {http://dx.doi.org/10.1016/j.mib.2013.07.002},
year = {2013}
}

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TY  - JOUR
AB  - The influence of the microbial–mammalian metabolic axis is becoming increasingly important for human health. Bacterial fermentation of carbohydrates (CHOs) and proteins produces short-chain fatty acids (SCFA) and a range of other metabolites including those from aromatic amino acid (AAA) fermentation. SCFA influence host health as energy sources and via multiple signalling mechanisms. Bacterial transformation of fibre-related phytochemicals is associated with a reduced incidence of several chronic diseases. The ‘gut–liver axis’ is an emerging area of study. Microbial deconjugation of xenobiotics and release of aromatic moieties into the colon can have a wide range of physiological consequences. In addition, the role of the gut microbiota in choline deficiency in non-alcoholic fatty liver disease (NAFLD) and insulin resistance is receiving increased attention.
AU  - Russell,WR
AU  - Hoyles,L
AU  - Flint,HJ
AU  - Dumas,ME
DO  - 10.1016/j.mib.2013.07.002
PY  - 2013///
TI  - Colonic bacterial metabolites and human health
T2  - Current Opinion in Microbiology
UR  - http://dx.doi.org/10.1016/j.mib.2013.07.002
UR  - http://hdl.handle.net/10044/1/12534
ER  - 

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