In this section
@article{Grech-Sollars:2018:10.1016/j.neuroimage.2018.06.059,
author = {Grech-Sollars, M and Zhou, F-L and Waldman, AD and Parker, GJM and Hubbard, Cristinacce PL},
doi = {10.1016/j.neuroimage.2018.06.059},
journal = {NeuroImage},
pages = {395--402},
title = {Stability and reproducibility of co-electrospun brain-mimicking phantoms for quality assurance of diffusion MRI sequences},
url = {http://dx.doi.org/10.1016/j.neuroimage.2018.06.059},
volume = {181},
year = {2018}
}
TY - JOUR
AB - Grey and white matter mimicking phantoms are important for assessing variations in diffusion MR measures at a single time point and over an extended period of time. This work investigates the stability of brain-mimicking microfibre phantoms and reproducibility of their MR derived diffusion parameters. The microfibres were produced by co-electrospinning and characterized by scanning electron microscopy (SEM). Grey matter and white matter phantoms were constructed from random and aligned microfibres, respectively. MR data were acquired from these phantoms over a period of 33 months. SEM images revealed that only small changes in fibre microstructure occurred over 30 months. The coefficient of variation in MR measurements across all time-points was between 1.6% and 3.4% for MD across all phantoms and FA in white matter phantoms. This was within the limits expected for intra-scanner variability, thereby confirming phantom stability over 33 months. These specialised diffusion phantoms may be used in a clinical environment for intra and inter-site quality assurance purposes, and for validation of quantitative diffusion biomarkers.
AU - Grech-Sollars,M
AU - Zhou,F-L
AU - Waldman,AD
AU - Parker,GJM
AU - Hubbard,Cristinacce PL
DO - 10.1016/j.neuroimage.2018.06.059
EP - 402
PY - 2018///
SN - 1053-8119
SP - 395
TI - Stability and reproducibility of co-electrospun brain-mimicking phantoms for quality assurance of diffusion MRI sequences
T2 - NeuroImage
UR - http://dx.doi.org/10.1016/j.neuroimage.2018.06.059
UR - http://hdl.handle.net/10044/1/61682
VL - 181
ER -
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Matthew Grech-Sollars
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Pete Lally