@article{Duffy:2020:10.1016/j.preghy.2020.06.005,
author = {Duffy, JMN and Cairns, AE and Magee, LA and von, Dadelszen P and van, 't Hooft J and Gale, C and Brown, M and Chappell, LC and Grobman, WA and Fitzpatrick, R and Karumanchi, SA and Lucas, DN and Mol, B and Stark, M and Thangaratinam, S and Wilson, MJ and Williamson, PR and Ziebland, S and McManus, RJ and International, Collaboration to Harmonise Outcomes for Pre-eclampsia iHOPE},
doi = {10.1016/j.preghy.2020.06.005},
journal = {Pregnancy Hypertension},
pages = {208--217},
title = {Standardising definitions for the pre-eclampsia core outcome set: A consensus development study},
url = {http://dx.doi.org/10.1016/j.preghy.2020.06.005},
volume = {21},
year = {2020}
}

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TY  - JOUR
AB  - OBJECTIVES: To develop consensus definitions for the core outcome set for pre-eclampsia. STUDY DESIGN: Potential definitions for individual core outcomes were identified across four formal definition development initiatives, nine national and international guidelines, 12 Cochrane systematic reviews, and 79 randomised trials. Eighty-six definitions were entered into the consensus development meeting. Ten healthcare professionals and three researchers, including six participants who had experience of conducting research in low- and middle-income countries, participated in the consensus development process. The final core outcome set was approved by an international steering group. RESULTS: Consensus definitions were developed for all core outcomes. When considering stroke, pulmonary oedema, acute kidney injury, raised liver enzymes, low platelets, birth weight, and neonatal seizures, consensus definitions were developed specifically for low- and middle-income countries because of the limited availability of diagnostic interventions including computerised tomography, chest x-ray, laboratory tests, equipment, and electroencephalogram monitoring. CONCLUSIONS: Consensus on measurements for the pre-eclampsia core outcome set will help to ensure consistency across future randomised trials and systematic reviews. Such standardization should make research evidence more accessible and facilitate the translation of research into clinical practice. Video abstract can be available at: www.dropbox.com/s/ftrgvrfu0u9glqd/6.%20Standardising%20definitions%20in%20teh%20pre-eclampsia%20core%20outcome%20set%3A%20a%20consensus%20development%20study.mp4?dl=0.
AU  - Duffy,JMN
AU  - Cairns,AE
AU  - Magee,LA
AU  - von,Dadelszen P
AU  - van,'t Hooft J
AU  - Gale,C
AU  - Brown,M
AU  - Chappell,LC
AU  - Grobman,WA
AU  - Fitzpatrick,R
AU  - Karumanchi,SA
AU  - Lucas,DN
AU  - Mol,B
AU  - Stark,M
AU  - Thangaratinam,S
AU  - Wilson,MJ
AU  - Williamson,PR
AU  - Ziebland,S
AU  - McManus,RJ
AU  - International,Collaboration to Harmonise Outcomes for Pre-eclampsia iHOPE
DO  - 10.1016/j.preghy.2020.06.005
EP  - 217
PY  - 2020///
SN  - 2210-7789
SP  - 208
TI  - Standardising definitions for the pre-eclampsia core outcome set: A consensus development study
T2  - Pregnancy Hypertension
UR  - http://dx.doi.org/10.1016/j.preghy.2020.06.005
UR  - https://www.ncbi.nlm.nih.gov/pubmed/32674052
UR  - http://hdl.handle.net/10044/1/81377
VL  - 21
ER  - 

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