@article{Pinchefsky:2021:10.1016/j.siny.2021.101268,
author = {Pinchefsky, EF and Schneider, J and Basu, S and Tam, EWY and Gale, C},
doi = {10.1016/j.siny.2021.101268},
journal = {Seminars in Fetal and Neonatal Medicine},
title = {Nutrition and management of glycemia in neonates with neonatal encephalopathy treated with hypothermia},
url = {http://dx.doi.org/10.1016/j.siny.2021.101268},
volume = {26},
year = {2021}
}

Download

TY  - JOUR
AB  - Adequate nutrition and glycemic homeostasis are increasingly recognized as potentially neuroprotective for the developing brain. In the context of hypoxia-ischemia, evidence is scarce regarding optimal nutritional support and administration route, as well as the short- and long-term consequences of such interventions. In this review, we summarize current knowledge on disturbances of brain metabolism of glucose and substrates by hypoxia-ischemia, and compound effects of these mechanisms on brain injury characterized by specific patterns on EEG and MRI. Risks and benefits of nutrition delivery via parenteral or enteral routes are examined. Nutrition could mitigate adverse neurodevelopmental outcomes, and the impact of nutritional strategies and specific nutritional interventions are reviewed. Limited literature highlights the need for further studies to understand the changes in energy metabolism during and after hypoxic-ischemic injury, to optimize nutritional regimens and glucose management, and to inform the neuroprotective role of nutrition.
AU  - Pinchefsky,EF
AU  - Schneider,J
AU  - Basu,S
AU  - Tam,EWY
AU  - Gale,C
DO  - 10.1016/j.siny.2021.101268
PY  - 2021///
SN  - 1084-2756
TI  - Nutrition and management of glycemia in neonates with neonatal encephalopathy treated with hypothermia
T2  - Seminars in Fetal and Neonatal Medicine
UR  - http://dx.doi.org/10.1016/j.siny.2021.101268
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000717544100008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/95369
VL  - 26
ER  - 

Download