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Journal articleUhm S, Alderdice F, Chambers B, et al., 2014,
PPO.23 Top 15 research priorities for preterm birth with clinicians and service users' involvement - outcomes from a James Lind Alliance priority setting partnership.
, Arch Dis Child Fetal Neonatal Ed, Vol: 99 Suppl 1Preterm birth is the single most important determinant of adverse infant outcomes in terms of survival, quality of life, psychosocial and emotional impact on the family, and health care costs. Research agenda in this area has been determined primarily by researchers, and the processes for priority setting in research have often lacked transparency.
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Journal articleGale C, Santhakumaran S, Wells J, et al., 2014,
PC.14 Adjustment of directly measured adipose tissue volume in infants.
, Arch Dis Child Fetal Neonatal Ed, Vol: 99 Suppl 1, Pages: A40-A41Direct measurement of adipose tissue using magnetic resonance imaging (MRI) is increasingly used to characterise body composition. Optimal techniques for adjusting direct measures of infant adipose tissue remain to be determined.
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Journal articleDarmasseelane K, Hyde MJ, Santhakumaran S, et al., 2014,
Mode of Delivery and Offspring Body Mass Index, Overweight and Obesity in Adult Life: A Systematic Review and Meta-Analysis (vol 9, e87896, 2014)
, PLOS ONE, Vol: 9, ISSN: 1932-6203 -
Journal articleGale C, Thomas EL, Jeffries S, et al., 2014,
Adiposity and hepatic lipid in healthy full-term, breastfed, and formula-fed human infants: a prospective short-term longitudinal cohort study
, American Journal of Clinical Nutrition, Vol: 99, Pages: 1034-1040, ISSN: 0002-9165Background: The effect of mode of infant feeding on adiposity deposition is not fully understood.Objective: The objective was to test the hypothesis that differences in total and regional adipose tissue content and intrahepatocellular lipid (IHCL) arise in early infancy between breast- and formula-fed infants and to describe longitudinal changes.Design: This prospective longitudinal cohort study was performed in 2 hospitals in the United Kingdom. Healthy, full-term, appropriate weight-for-gestational age infants were recruited; adipose tissue volume and distribution were directly quantified by using whole-body magnetic resonance imaging; IHCL was assessed by in vivo proton magnetic resonance spectroscopy. Measurements were performed after birth (median age: 13 d) and at 6–12 wk of age. Method of infant feeding was recorded prospectively by using maternally completed feeding diaries. Breastfed was defined as >80% of feeds consisting of breast milk at both points; formula-fed was defined as >80% of feeds consisting of formula milk at both points.Results: Longitudinal results were obtained from 70 infants (36 breastfed, 9 mixed-fed, and 25 formula-fed). No differences were found in total or regional adipose tissue or IHCL between breastfed and formula-fed infants. In pooled analyses including all feeding groups, IHCL and total adipose tissue approximately doubled between birth and 6–12 wk: IHCL after birth (median: 0.949; IQR: 0.521–1.711) and at 6–12 wk (1.828; 1.376–2.697; P < 0.001) and total adipose tissue after birth (0.749 L; 0.620–0.928 L) and at 6–12 wk (1.547 L; 1.332–1.790 L; P < 0.001). Increasing adiposity was characterized by greater relative increases in subcutaneous than in internal adipose tissue depots.Conclusions: No differences were detectable in adipose tissue or IHCL accretion between breastfed and formula-fed infants up to 2 mo. The substantial increase in IHCL seen over this period in bo
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Journal articleWong HS, Santhakumaran S, Statnikov Y, et al., 2014,
Retinopathy of prematurity in English neonatal units: a national population-based analysis using NHS operational data
, ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, Vol: 99, Pages: F196-F202, ISSN: 1359-2998- Author Web Link
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- Citations: 18
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Journal articleGale C, Santhakumaran S, Wells JCK, et al., 2014,
Adjustment of directly measured adipose tissue volume in infants
, International Journal of Obesity, Vol: 38, Pages: 995-999, ISSN: 1476-5497 -
Journal articleShah PS, Lee SK, Lui K, et al., 2014,
The International Network for Evaluating Outcomes of very low birth weight, very preterm neonates (iNeo): a protocol for collaborative comparisons of international health services for quality improvement in neonatal care
, BMC PEDIATRICS, Vol: 14- Author Web Link
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- Citations: 56
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Journal articleDarmasseelane K, Hyde MJ, Santhakumaran S, et al., 2014,
Mode of Delivery and Offspring Body Mass Index, Overweight and Obesity in Adult Life: A Systematic Review and Meta-Analysis
, PLOS One, Vol: 9, ISSN: 1932-6203 -
Journal articleThangarajah D, Chappell KE, Gale C, et al., 2014,
MRI assessment of body composition in paediatric Crohn's disease; intra-abdominal adipose tissue association with disease severity
, JOURNAL OF CROHNS & COLITIS, Vol: 8, Pages: S239-S239, ISSN: 1873-9946- Author Web Link
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- Citations: 3
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Journal articleWong HS, Huertas-Ceballos A, Cowan FM, et al., 2014,
Evaluation of Early Childhood Social-Communication Difficulties in Children Born Preterm Using the Quantitative Checklist for Autism in Toddlers
, JOURNAL OF PEDIATRICS, Vol: 164, Pages: 26-+, ISSN: 0022-3476- Author Web Link
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- Citations: 39
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