A chapter on Chiral Lewis Base Activation of Acyl & Related Donors in Enantioselective Transformations by James Murray and Zsofia Heckenast goes live
James I. Murray, Zsofia Heckenast, and Alan C. Spivey, 'Chiral Lewis Base Activation of Acyl and Related Donors in Enantioselective Transformations (n to π*)', in Lewis base catalysis in organic Synthesis, 3 Volume Set, Ed's E. Vedejs and S.E. Denmark, Wiley, 2016, Chapter 12, Volume 2, Section III - Applications: Lewis Base Catalysis Involving an n to π* Activation Step, pp 457-526. ISBN: 978-3-527-33618-0; DOI: 10.1002/9783527675142.ch12.
This chapter is a fairly comprehensive account of chiral Lewis base acylation reactions and related transformations organised by catalyst structural class. The contents encompasses:
12.1 Introduction
12.2 Phosphine Catalysts
12.2.1 Aryl/alkyl phosphine-based
12.3 Amine Catalysts
12.3.1 Pyrrole and 4-dialkylaminopyridine based
12.3.2 Imidazole based
12.3.3 Diamine-based
12.3.4 Cinchona alkaloid-based
12.3.5 Amidine and isothiourea-based
12.4 N-Heterocyclic carbene catalysts
12.4.1 Thiazolium and triazolium-based
12.5 Alcohol catalysts
12.5.1 sec-Alcohol-based
12.5.2 Phenoxide-based
12.5.3 Hydroxamic acid-based
12.6 Concluding Remarks
12.7 References
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Reporter
Professor Alan C Spivey
Department of Chemistry
Contact details
Tel: +44 (0)20 7594 5841
Email: a.c.spivey@imperial.ac.uk
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