

A tribute to Sir James Stoddart, a towering figure in the field of chemistry and molecular machines, who passed on 30 December 2024 at the age of 82.
A tribute to Sir James Fraser Stoddart, a towering figure in the field of chemistry and molecular machines, who passed on 30 December 2024 at the age of 82.
Sir Fraser was a Nobel Laureate in Chemistry, recognised globally for his pioneering work in the design and synthesis of ‘molecular machines’ – molecules that can convert chemical energy into movements.
Sir Fraser’s legacy at Imperial College London began in the 1970s when he worked closely with X-ray crystallography experts at Imperial. In 2013, Sir Fraser established The Fraser and Norma Stoddart Prize to honour his late wife, Norma, and recognise students who demonstrate exemplary citizenship.
This prize rewards academically excellent students who also demonstrate exemplary citizenship through volunteering, student activity organisation, mentorship and entrepreneurship.
Lasting scientific impact
A visionary scientist, Sir Fraser foresaw the potential of nanotechnology early in his career. His groundbreaking research included the development of rotaxanes, Borromean rings, and catenanes which have propelled advances in targeted drug delivery and energy storage solutions.
Sir Fraser’s influence extended beyond the laboratory. Professor Oscar Ces, the Head of Chemistry, highlighted his impact on the field of chemistry: “Sir Fraser Stoddart was a truly remarkable scientist and a wonderful citizen who touched the lives of so many. His ground-breaking research on the synthesis of molecular machines has inspired generations of researchers and unlocked a treasure trove of fundamental breakthroughs and translational opportunities. In parallel, the personal support and mentoring he has given to scientists across the globe has transformed countless careers.”
Sir Fraser is survived by his two daughters, Fiona and Alison who both graduated with First Class Honours in Chemistry – one from the University of Cambridge and the other from Imperial.
“Those at Imperial College who knew and worked with him always speak of him in the most glowing of terms and he will be greatly missed. Our sincerest condolences go out to his family and friends," said Professor Ces.
Article text (excluding photos or graphics) © Imperial College London.
Photos and graphics subject to third party copyright used with permission or © Imperial College London.
Reporters

Jacklin Kwan
Faculty of Natural Sciences

Saida Mahamed
Department of Chemistry