Cancer cell killer
A novel platinum(II) compound with anticancer activity
A novel Pt complex which interacts non-covalently with DNA and induces cell death (via a different mechanism than cisplatin) has been developed.
A novel platinum(II) compound with anticancer activity
A novel Pt complex which interacts non-covalently with DNA and induces cell death (via a different mechanism than cisplatin) has been developed.
Optical probe for quadruplex DNA
We report on a Pt complex that targets quadruplex DNA selectively and switches-on its emission upon binding (Chem Eur J, 2012, 18,16277)
New paper on oxidative damage of DNA published
We report on a new tri-copper complex that cleaves DNA very efficiently without need for external co-reductants (Chem Eur J, 2012, 18, 15133).