In this section
@article{Johansson:2016:10.12688/f1000research.9637.1,
author = {Johansson, C},
doi = {10.12688/f1000research.9637.1},
journal = {F1000Research},
title = {Respiratory syncytial virus infection: an innate perspective.},
url = {http://dx.doi.org/10.12688/f1000research.9637.1},
volume = {5},
year = {2016}
}
TY - JOUR
AB - Respiratory syncytial virus (RSV) is a common cause of upper respiratory tract infection in children and adults. However, infection with this virus sometimes leads to severe lower respiratory disease and is the major cause of infant hospitalisations in the developed world. Several risk factors such as baby prematurity and congenital heart disease are known to predispose towards severe disease but previously healthy, full-term infants can also develop bronchiolitis and viral pneumonia during RSV infection. The causes of severe disease are not fully understood but may include dysregulation of the immune response to the virus, resulting in excessive recruitment and activation of innate and adaptive immune cells that can cause damage. This review highlights recent discoveries on the balancing act of immune-mediated virus clearance versus immunopathology during RSV infection.
AU - Johansson,C
DO - 10.12688/f1000research.9637.1
PY - 2016///
SN - 2046-1402
TI - Respiratory syncytial virus infection: an innate perspective.
T2 - F1000Research
UR - http://dx.doi.org/10.12688/f1000research.9637.1
UR - http://www.ncbi.nlm.nih.gov/pubmed/28105323
UR - http://hdl.handle.net/10044/1/48183
VL - 5
ER -
