M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza. - Cole, SL; Dunning, J; Kok, WL; Benam, KH; Benlahrech, A; Repapi, E; Martinez, FO; Drumright, L; Powell, TJ; Bennett, M; Elderfield, R; Thomas, C; et al. (JCI Insight, 2017)