BibTex format
@article{Whittaker:2021:10.1101/2021.04.09.21255199,
author = {Whittaker, HR and Gulea, C and Koteci, A and Kallis, C and Morgan, AD and Iwundu, C and Weeks, M and Gupta, R and Quint, JK},
doi = {10.1101/2021.04.09.21255199},
title = {Post-acute COVID-19 sequelae in cases managed in the community or hospital in the UK: a population based study},
url = {http://dx.doi.org/10.1101/2021.04.09.21255199},
year = {2021}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - <jats:title>Abstract</jats:title><jats:sec><jats:title>Objective</jats:title><jats:p>To compare post-COVID-19 sequelae between hospitalised and non-hospitalised individuals</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>Population-based cohort study</jats:p></jats:sec><jats:sec><jats:title>Setting</jats:title><jats:p>1,383 general practices in England contributing to Clinical Practice Research Database Aurum</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>46,687 COVID-19 cases diagnosed between 1<jats:sup>st</jats:sup> August to 17<jats:sup>th</jats:sup> October 2020 (45.4% male; mean age 40), either hospitalised within two weeks of diagnosis or non-hospitalised, and followed-up for a maximum of three months.</jats:p></jats:sec><jats:sec><jats:title>Main outcome measures</jats:title><jats:p>Event rates of new symptoms, diseases, prescriptions and healthcare utilisation in hospitalised and non-hospitalised individuals, with between-group comparison using Cox regression. Outcomes compared at 6 and 12 months prior to index date, equating to first UK wave and pre-pandemic. Non-hospitalised group outcomes stratified by age and sex.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>45,272 of 46,687 people were non-hospitalised; 1,415 hospitalised. Hospitalised patients had higher rates of 13/26 symptoms and 11/19 diseases post-COVID-19 than the community group, received more prescriptions and utilised more healthcare. The largest differences were noted for rates per 100,000 person-weeks [95%CI] of <jats:italic>breathlessness:</jats:italic> 536 [432 to 663] v. 85 [77 to 93]; <jats:italic>joint pain:</jats:italic> 295 [221 to 392] v. 168 [158 to 179]
AU - Whittaker,HR
AU - Gulea,C
AU - Koteci,A
AU - Kallis,C
AU - Morgan,AD
AU - Iwundu,C
AU - Weeks,M
AU - Gupta,R
AU - Quint,JK
DO - 10.1101/2021.04.09.21255199
PY - 2021///
TI - Post-acute COVID-19 sequelae in cases managed in the community or hospital in the UK: a population based study
UR - http://dx.doi.org/10.1101/2021.04.09.21255199
ER -