@article{Hargreaves:2022:10.1016/j.lanepe.2022.100471,
author = {Hargreaves, JR and Langan, SM and Oswald, WE and Halliday, KE and Sturgess, J and Phelan, J and Nguipdop-Djomo, P and Ford, B and Allen, E and Sundaram, N and Ireland, G and Poh, J and Ijaz, S and Diamond, I and Rourke, E and Dawe, F and Judd, A and Warren-Gash, C and Clark, TG and Glynn, JR and Edmunds, WJ and Bonell, C and Mangtani, P and Ladhani, SN and Abramsky, T and Ahmad, S and Aiano, F and Baawuah, F and Bankiewicz, U and Batt, S and Beckmann, J and Bhavsar, A and Brent, B and Brent, A and Brouwer, S and Brown, K and Browne, R and Childs, K and Cook, S and Cousens, S and Day, I and Felton, A and Fine, P and Foster, D and Garstang, J and Gates, D and Grant, C and Griffiths-Tong, B and Hele, C and Hemsi, R and Jones, P and Jordan, H and Kucharski, A and Lacey, A and Leeson, R and Lelii, F and Lovely, P and Lunskey, M and McLanachan, C and Munday, J and Okike, I and O'Reilly, K and Parker, P and Powell, A and Proud, S and Ramsay, M and Rudd, L and Russell, T and Shute, J and Tilou},
doi = {10.1016/j.lanepe.2022.100471},
journal = {The Lancet Regional Health - Europe},
title = {Epidemiology of SARS-CoV-2 infection among staff and students in a cohort of English primary and secondary schools during 2020–2021},
url = {http://dx.doi.org/10.1016/j.lanepe.2022.100471},
volume = {21},
year = {2022}
}

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TY  - JOUR
AB  - Background: There remains uncertainty about the epidemiology of SARS-CoV-2 among school students and staff and the extent to which non-pharmaceutical-interventions reduce the risk of school settings. Methods: We conducted an open cohort study in a sample of 59 primary and 97 secondary schools in 15 English local authority areas that were implementing government guidance to schools open during the pandemic. We estimated SARS-CoV-2 infection prevalence among those attending school, antibody prevalence, and antibody negative to positive conversion rates in staff and students over the school year (November 2020–July 2021). Findings: 22,585 staff and students participated. SARS-CoV-2 infection prevalence among those attending school was highest during the first two rounds of testing in the autumn term, ranging from 0.7% (95% CI 0.2, 1.2) among primary staff in November 2020 to 1.6% (95% CI 0.9, 2.3) among secondary staff in December 2020. Antibody conversion rates were highest in the autumn term. Infection patterns were similar between staff and students, and between primary and secondary schools. The prevalence of nucleoprotein antibodies increased over the year and was lower among students than staff. SARS-CoV-2 infection prevalence in the North-West region was lower among secondary students attending school on normal school days than the regional estimate for secondary school-age children. Interpretation: SARS-CoV-2 infection prevalence in staff and students attending school varied with local community infection rates. Non-pharmaceutical interventions intended to prevent infected individuals attending school may have partially reduced the prevalence of infection among those on the school site. Funding: UK Department of Health and Social Care.
AU  - Hargreaves,JR
AU  - Langan,SM
AU  - Oswald,WE
AU  - Halliday,KE
AU  - Sturgess,J
AU  - Phelan,J
AU  - Nguipdop-Djomo,P
AU  - Ford,B
AU  - Allen,E
AU  - Sundaram,N
AU  - Ireland,G
AU  - Poh,J
AU  - Ijaz,S
AU  - Diamond,I
AU  - Rourke,E
AU  - Dawe,F
AU  - Judd,A
AU  - Warren-Gash,C
AU  - Clark,TG
AU  - Glynn,JR
AU  - Edmunds,WJ
AU  - Bonell,C
AU  - Mangtani,P
AU  - Ladhani,SN
AU  - Abramsky,T
AU  - Ahmad,S
AU  - Aiano,F
AU  - Baawuah,F
AU  - Bankiewicz,U
AU  - Batt,S
AU  - Beckmann,J
AU  - Bhavsar,A
AU  - Brent,B
AU  - Brent,A
AU  - Brouwer,S
AU  - Brown,K
AU  - Browne,R
AU  - Childs,K
AU  - Cook,S
AU  - Cousens,S
AU  - Day,I
AU  - Felton,A
AU  - Fine,P
AU  - Foster,D
AU  - Garstang,J
AU  - Gates,D
AU  - Grant,C
AU  - Griffiths-Tong,B
AU  - Hele,C
AU  - Hemsi,R
AU  - Jones,P
AU  - Jordan,H
AU  - Kucharski,A
AU  - Lacey,A
AU  - Leeson,R
AU  - Lelii,F
AU  - Lovely,P
AU  - Lunskey,M
AU  - McLanachan,C
AU  - Munday,J
AU  - Okike,I
AU  - O'Reilly,K
AU  - Parker,P
AU  - Powell,A
AU  - Proud,S
AU  - Ramsay,M
AU  - Rudd,L
AU  - Russell,T
AU  - Shute,J
AU  - Tilouche,N
AU  - Virgin,C
AU  - Wyatt,SE
AU  - YEO,K
DO  - 10.1016/j.lanepe.2022.100471
PY  - 2022///
TI  - Epidemiology of SARS-CoV-2 infection among staff and students in a cohort of English primary and secondary schools during 2020–2021
T2  - The Lancet Regional Health - Europe
UR  - http://dx.doi.org/10.1016/j.lanepe.2022.100471
VL  - 21
ER  - 

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