Supervisor: Dr Bill Proud (with assistance from Dr Kate Brown, Dr Spyros Masouros Imperial Blast)
This is an unusual PhD opportunity which will be carried out in the Institute of Shock Physics in association with the Imperial Blast Biomechanics and Biophysics Group.
Although a considerable amount of research is being undertaken in studying the effects of shock pressures upon metals and other 'hard' materials, there is considerable interest in expanding shock physics research in studying soft condensed matter systems. A quick review of the literature will show that while polymers and organic liquids will start to bulk decompose at shock pressures of ~20 GPa. This is a result of widespread bond cleavage due to increased temperature. It is also well known that biological materials cannot survive to these high-pressure levels and much smaller pulses will cause marked changes. It is the aim of this study to take complex organic materials, including cells, and apply mechanical stimuli in order to track these changes.
The project will involve the development of equipment to be used in conjunction with existing impact facilities available at the ISP for studying physiologically relevant effects of shock waves in biological cell and tissues. Considerable emphasis will be placed upon development of an improved understanding of the physical processes involved in shock wave transmission through these materials, including a characterisation of damage using existing models for hard and soft condensed matter.
The PhD is expected to have a background in physical sciences or engineering but have an interest in biological research. The project will involve interactions with researchers with varied backgrounds in shock physics, engineering and biology. There will be a strong emphasis on experimental studies although some modelling will also be undertaken. Applicants should have a first or upper second class UK honours degree (or equivalent) in materials science, mechanical engineering, chemistry, physics or similar discipline.