BibTex format
@article{Maddocks:2025:10.1098/rsos.241537,
author = {Maddocks, J and Mahesh, M and Sampani, SI and Dixon, AC and Nielsen, CD-T and Kumar, P and Akien, GR and Spencer, J and Abdul-Sada, A and Turner, JFC and Spivey, AC and Kostakis, GE},
doi = {10.1098/rsos.241537},
journal = {R Soc Open Sci},
title = {Single enantiomer propeller-shaped polynuclear complexes as catalysts-proof-of-concept for enantioinduction in a Michael addition reaction.},
url = {http://dx.doi.org/10.1098/rsos.241537},
volume = {12},
year = {2025}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - We report a family of propeller-shaped polynuclear metal complexes whose overall chirality is dictated by a single stereogenic centre within their component amino alcohol-ligand. These topologically intriguing complexes are readily prepared in enantiomerically pure form and are shown here to catalyse the conjugate addition of barbituric acids and their derivatives to nitroalkenes, with a catalyst loading of 1 mol%. Although only low levels of enantioinduction are observed, control experiments indicate that the enantioselectivity is dictated by the overall topology of the complex and not governed by binding to the tetrametallic entity, heralding a potentially new mode of catalysis.
AU - Maddocks,J
AU - Mahesh,M
AU - Sampani,SI
AU - Dixon,AC
AU - Nielsen,CD-T
AU - Kumar,P
AU - Akien,GR
AU - Spencer,J
AU - Abdul-Sada,A
AU - Turner,JFC
AU - Spivey,AC
AU - Kostakis,GE
DO - 10.1098/rsos.241537
PY - 2025///
SN - 2054-5703
TI - Single enantiomer propeller-shaped polynuclear complexes as catalysts-proof-of-concept for enantioinduction in a Michael addition reaction.
T2 - R Soc Open Sci
UR - http://dx.doi.org/10.1098/rsos.241537
UR - https://www.ncbi.nlm.nih.gov/pubmed/40151485
VL - 12
ER -