Brain fluid surgery to a world-first lunar-Earth flyby: News from Imperial
Professor Jonathan Weber reflects on his time as AHSC Director
Food allergy doubles in the UK over last decade but many still without treatment
04 June 2024
NAD+ precursor probes as tools for profiling intracellular ADP-ribosylation
27 July 2023
Poster Presentation Award
20 July 2023
New database of drug targets will help fight incurable diseases
30 June 2023
Using bacterial toolkits to power research
22 May 2023
New partnership will use molecular glues to tackle ‘undruggable’ disease targets
20 February 2023
UV-light activated probe finds new interactions in living cells
25 November 2022
Our KLK6 activity-based probes now published in JACS!
02 November 2022
CRISPR-based oligo recombineering in drug discovery
20 October 2022
Blocking poxvirus infectiousness with NMT inhibitors
21 September 2022
Light-mediated multi-target protein degradation using photoswitching
01 February 2022
Identification of the first covalent ligands of the small GTPase Rab27A
17 June 2021
Activity-based probes to dissect the KLK activome in prostate cancer
07 June 2021
A probe for NLRP3 inflammasome inhibitor MCC950 identifies CA2 as novel target
27 April 2021
Identification of a small-molecule inhibitor binding site in HHAT
20 April 2021
How to identify which proteases are cleaving a protein of interest
09 April 2021
PROTACs, molecular glues and bifunctionals from bench to bedside
30 November 2020
Review article on light-activated PROTACs
17 August 2020
An overview of activity-based protein profiling and recent advances
15 June 2020
Targeting STAT3 signaling in ER-positive breast cancer
04 June 2020
Peptide probes for Plasmodium falciparum MTIP
29 May 2020
N-myristoyltransferase inhibitors against wheat pathogen Zymoseptoria tritici
18 May 2020
A new antibody-PROTAC combination can selectively target Breast Cancer cells
26 April 2020
A caged E3 ligase ligand for PROTAC-mediated protein degradation
24 February 2020
A cell-active probe for PARP inhibitors
19 September 2019
First Tate group publication targeting DNA repair in antibiotic resistance
15 August 2019
Acyl-cLIP: a universal assay for lipidation enzymes
18 April 2019
The good, the bad and the ugly: chemical probes for human NMT
17 April 2019
Probing Collaboration